期刊
APPLIED SURFACE SCIENCE
卷 539, 期 -, 页码 -出版社
ELSEVIER
DOI: 10.1016/j.apsusc.2020.148286
关键词
Black phosphorus electrodes; Electrochemistry; Microwave synthesis; Pathogen detection; Haemophilus Influenzae
类别
资金
- Polish National Science Centre [2016/22/E/ST7/00102]
- National Centre for Science and Development [347324/12/NCBR/2017]
- Faculty of Electronics, Telecommunications and Informatics of the Gdansk University of Technology
Various passivation schemes were applied to few-layer black phosphorus for covalent functionalisation, improving its electrochemical response. Thermal and microwave assisted modification in different solvents resulted in high reversibility of reactions. Functionalisation limited degradation under ambient conditions and provided a potential linker for protein bonding.
In this paper, various passivation schemes were applied at few-layer black phosphorus (FLBP) to achieve covalent functionalisation with 4-azidobenzoic acid, improving its electrochemical response intended for analytical and biosensing applications. The thermal and microwave assisted modification procedures in toluene and dimethylformamide resulted in high reversibility of reactions on functionalised FLBP using a ferricyanide/ferrocyanide redox probe. The lowest peak-to-peak separation of 91 mV, and high kinetics were obtained by thermal synthesis in dimethylformamide. Attachment of a = N-phenylene-COOH moiety to the FLBP limits its degradation under ambient conditions delivering a linker for a peptide bond with proteins in the -NH2 groups. The functionalised FLBP was applied for impedimetric detection of the Haemophilus Influenzae (HI) bacterial protein with a low limit of detection (LOD) of 5.82 mu g mL(-1) along with high sensitivity equal to 1.267% mu g(-1) mL. The proposed strategy delivers a novel phosphorene-based electrode for sensitive detection of various bacterial pathogens.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据