4.8 Article

Enrichment-Detection Integrated Exosome Profiling Biosensors Promising for Early Diagnosis of Cancer

期刊

ANALYTICAL CHEMISTRY
卷 93, 期 11, 页码 4697-4706

出版社

AMER CHEMICAL SOC
DOI: 10.1021/acs.analchem.0c05245

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资金

  1. National Key RD Plan of China [2017YFB0405400]
  2. Major Innovation Projects in Shandong Province [2018YFJH0503]
  3. Natural Science Foundation for Distinguished Young Scientist of Shandong Province [JQ201814]
  4. Natural Science Foundation for Young Scientists of China [61701282]
  5. Qi lu Young Scholar Funds [11500086963060]
  6. Shandong University Multidisciplinary Research and Innovation Team of Young Scholars
  7. Collaborative Innovation Center of Technology and Equipment for Biological Diagnosis and Therapy in Universities of Shandong

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This Feature discusses the working fundamentals, advanced strategies, and future outlook and challenges of enrichment-detection integrated biosensors for exosome profiling.
Enrichment-detection integrated biosensors for exosome profiling have shown great potential in noninvasive diagnosis and point-of-care testing with the advantage of multifunctions. This Feature focuses on the enrichment-detection integrated exosome profiling biosensors emphasizing (i) the underlying working fundamentals of these sorts of biosensors, (ii) four advanced strategies developed for exosome analysis, and (iii) future outlook and present challenges of exosome profiling systems.

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