期刊
ANALYTICAL CHEMISTRY
卷 93, 期 8, 页码 3822-3829出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.analchem.0c04326
关键词
-
资金
- Grundfos Foundation
- Sapere Aude grant from the Independent Research Fund Denmark (IRFD) [DFF-804800057B]
- ERASMUS+ internship grant
Combining electrochemical and optical sensors allows for a dynamic sensing concept for buffer capacity evaluation by modulating the pH microenvironment using water electrolysis. This approach enables quick assessment of concentration of different buffer species and in situ determination of the apparent pK value of specific buffer solutions under ambient conditions.
State-of-the-art electrochemical and optical sensors present distinct advantages and disadvantages when used individually. Combining both methodologies offers interesting synergies and makes it possible to exploit strengths and circumvent possible problems of the individual methods. We report a dynamic sensing concept for buffer capacity by applying water electrolysis to modulate the pH microenvironment in front of an optical pH sensor placed in a flow cell. Using this combinatory approach in a nonequilibrium readout mode allowed us to assess the concentration of different buffer species in relatively short time (1 min per measurement). Theoretical simulations of the system were performed to validate the presented method. Additionally, the dynamic measurement approach enabled in situ determination of the apparent pK, of MOPS (3-(N-morpholino)propanesulfonic acid) buffer at ambient conditions. The dynamic and combinatory approach presented here holds large potential also for other pH-active analytes.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据