期刊
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
卷 413, 期 18, 页码 4581-4598出版社
SPRINGER HEIDELBERG
DOI: 10.1007/s00216-020-03138-x
关键词
Molecular imprinting; MIP; Sensor; Bacteria
资金
- McGill University
Foodborne diseases caused by bacterial pathogens are a growing threat to public health worldwide. Rapid detection of pathogenic bacteria is crucial for disease prevention and food safety. Biosensors integrating molecular imprinted polymers and sensor platforms are promising candidates for highly sensitive and selective detection of pathogenic bacteria.
Foodborne diseases caused by bacterial pathogens pose a widespread and growing threat to public health in the world. Rapid detection of pathogenic bacteria is of great importance to prevent foodborne diseases and ensure food safety. However, traditional detection methods are time-consuming, labour intensive and expensive. In recent years, many attempts have been made to develop alternative methods for bacterial detection. Biosensors integrated with molecular imprinted polymers (MIPs) and various transducer platforms are among the most promising candidates for the detection of pathogenic bacteria in a highly sensitive, selective and ultra-rapid manner. In this review, we summarize the most recent advances in molecular imprinting for bacterial detection, introduce the underlying recognition mechanisms and highlight the applications of MIP-based biosensors. In addition, the challenges and future perspectives are discussed with the aim of accelerating the development of MIP-based biosensors and extending their applications.
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