4.7 Article

Plasma β-secretase1 concentrations correlate with basal forebrain atrophy and neurodegeneration in cognitively healthy individuals at risk for AD

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Neurosciences

The β-Secretase BACE1 in Alzheimer's Disease

Harald Hampel et al.

Summary: BACE1 is a well-validated therapeutic target for slowing down Aβ production in early AD, despite previous clinical trials being discontinued. Further research should focus on the roles of BACE1 and Aβ in physiological and pathophysiological processes, as well as the substrates and downstream effects of BACE1 and BACE2.

BIOLOGICAL PSYCHIATRY (2021)

Review Neurosciences

The Alzheimer Precision Medicine Initiative

Harald Hampel et al.

JOURNAL OF ALZHEIMERS DISEASE (2019)

Review Clinical Neurology

Blood-based biomarkers for Alzheimer disease: mapping the road to the clinic

Harald Hampel et al.

NATURE REVIEWS NEUROLOGY (2018)

Article Neurosciences

Plasma Tau Association with Brain Atrophy in Mild Cognitive Impairment and Alzheimer's Disease

Kacie D. Deters et al.

JOURNAL OF ALZHEIMERS DISEASE (2017)

Article Psychology, Mathematical

Evaluating significance in linear mixed-effects models in R

Steven G. Luke

BEHAVIOR RESEARCH METHODS (2017)

Review Clinical Neurology

Statistical Approaches to Longitudinal Data Analysis in Neurodegenerative Diseases: Huntington's Disease as a Model

Tanya P. Garcia et al.

CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS (2017)

Article Neuroimaging

Basal forebrain atrophy correlates with amyloid beta burden in Alzheimer's disease

Georg M. Kerbler et al.

NEUROIMAGE-CLINICAL (2015)

Article Clinical Neurology

Basal forebrain atrophy and cortical amyloid deposition in nondemented elderly subjects

Michel J. Grothe et al.

ALZHEIMERS & DEMENTIA (2014)

Article Neurosciences

Subregional Basal Forebrain Atrophy in Alzheimer's Disease: A Multicenter Study

Ingo Kilimann et al.

JOURNAL OF ALZHEIMERS DISEASE (2014)

Review Clinical Neurology

Targeting the β secretase BACE1 for Alzheimer's disease therapy

Riqiang Yan et al.

LANCET NEUROLOGY (2014)

Article Clinical Neurology

Dissecting phenotypic traits linked to human resilience to Alzheimer's pathology

Beatriz G. Perez-Nievas et al.

Article Health Care Sciences & Services

Multiple imputation of missing values was not necessary before performing a longitudinal mixed-model analysis

Jos Twisk et al.

JOURNAL OF CLINICAL EPIDEMIOLOGY (2013)

Article Neurosciences

BACE1 Activity in Cerebrospinal Fluid and Its Relation to Markers of AD Pathology

Sandra D. Mulder et al.

JOURNAL OF ALZHEIMERS DISEASE (2010)

Article Clinical Neurology

Basal forebrain atrophy is a presymptomatic marker for Alzheimer's disease

Andrew M. Hall et al.

ALZHEIMERS & DEMENTIA (2008)

Article Clinical Neurology

Elevated cerebrospinal fluid BACE1 activity in incipient Alzheimer disease

Henrik Zetterberg et al.

ARCHIVES OF NEUROLOGY (2008)