Potentially modifiable risk factors for slow gait in community-dwelling older adults: A systematic review

Purpose: Slow gait speed in older adults is associated with increased risk for falls and fractures, functional dependence, multimorbidity, and even mortality. The risk of these adverse outcomes can be reduced by intervening on potentially modifiable risk factors. The purpose of this systematic review was to identify potentially modifiable risk factors associated with slow gait speed and clinically meaningful gait speed decline in older community-dwelling adults. Methods: Literature searches were conducted in MEDLINE, EMBASE, and CINAHL, Google Scholar, and in the bibliographies of retrieved articles. Results: Forty studies met the inclusion criteria for qualitative review. Study designs were cross-sectional and longitudinal. Operational definitions of 'slow gait' and 'meaningful gait speed decline' were variable and based on sample distributions (e.g. quartiles), external criteria (e.g. < 0.8 m/s), and dynamic changes over time (e. g. >= 0.05 m/s decline per year). Twenty-six potentially modifiable risk factors were assessed in at least two studies. The risk factors most commonly investigated and that showed significant associations with slow gait and/or meaningful gait speed decline include physical activity, education, body mass index-obesity, pain, and depression/depressive symptoms. Conclusion: Our results suggest that there are modifiable targets to maintain gait speed that are amenable to potential treatment.

Automated summary

This systematic review aimed to identify potentially modifiable risk factors associated with slow gait speed and clinically meaningful gait speed decline in older community-dwelling adults. The results suggest that physical activity, education level, body mass index-obesity, pain, and depression/depressive symptoms are commonly investigated risk factors showing significant associations with slow gait and/or meaningful gait speed decline. The findings support the idea that there are modifiable targets for maintaining gait speed that can be targeted for potential treatment.