期刊
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA
卷 100, 期 6, 页码 1034-1039出版社
WILEY
DOI: 10.1111/aogs.14130
关键词
coronavirus disease 2019; fetal Doppler; fetal growth; growth velocity; SARS‐ CoV‐ 2; severe acute respiratory syndrome coronavirus 2 infection; uterine artery Doppler
Pregnancies complicated by SARS-CoV-2 infection do not have a higher risk of fetal growth restriction through impaired placental function, and increased fetal surveillance is not supported based on the findings from this study.
Introduction Our objective was to compare the fetal growth velocity and fetal hemodynamics in pregnancies complicated and in those not complicated by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Material and methods Prospective case-control study of consecutive pregnancies complicated by SARS-CoV-2 infection during the second half of pregnancy matched with unaffected women. The z scores of head circumference, abdominal circumference, femur length, and estimated fetal weight were compared between the two groups. Fetal growth was assessed by analyzing the growth velocity of head circumference, abdominal circumference, femur length, and estimated fetal weight between the second- and third-trimester scans. Similarly, changes in the pulsatility index of uterine, umbilical, and middle cerebral arteries, and their ratios were compared between the two study groups. Results Forty-nine consecutive pregnancies complicated, and 98 not complicated, by SARS-CoV-2 infection were included. General baseline and pregnancy characteristics were similar between pregnant women with and those without SARS-CoV-2 infection. There was no difference in head circumference, abdominal circumference, femur length, and estimated fetal weight z scores between pregnancies complicated and those not complicated by SARS-CoV-2 infection at both the second- and third-trimester scans. Likewise, there was no difference in the growth velocity of all these body parameters between the two study groups. Finally, there was no difference in the pulsatility index of both maternal and fetal Doppler scans throughout gestation between the two groups. Conclusions Pregnancies complicated by SARS-CoV-2 infection are not at higher risk of developing fetal growth restriction through impaired placental function. The findings from this study do not support a policy of increased fetal surveillance in these women.
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