Spiny mouse (Acomys): an emerging research organism for regenerative medicine with applications beyond the skin

The spiny mouse (Acomys species) has emerged as an exciting research organism due to its remarkable ability to undergo scarless regeneration of skin wounds and ear punches. Excitingly, Acomys species demonstrate scar-free healing in a wide-range of tissues beyond the skin. In this perspective article, we discuss published findings from a variety of tissues to highlight how this emerging research organism could shed light on numerous clinically relevant human diseases. We also discuss the challenges of working with this emerging research organism and suggest strategies for future Acomys-inspired research.

Automated summary

The spiny mouse is an exciting research organism due to its remarkable scarless healing abilities in various tissues beyond the skin, which could shed light on numerous clinically relevant human diseases. However, there are challenges in working with this emerging research organism that require future strategies and methods.