4.7 Article

Limiting Genotype Frequencies of Y-Linked Genes with a Mutant Allele in a Two-Sex Population

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Article Biochemical Research Methods

Bayesian Inference in Y-Linked Two-Sex Branching Processes with Mutations: ABC Approach

Miguel Gonzalez et al.

Summary: The study analyzes the evolution of Y-linked allele carriers and mutations using a Y-linked two-sex branching process model, estimating main parameters through Bayesian inference. By observing total number of females, males, males of each genotype in last generation, and introducing information on mutated males in last generation, the study approximates the posterior distributions of model parameters using Approximate Bayesian Computation (ABC). Illustrations and discussion on accuracy of the procedure based on simulated examples are provided.

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