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Origami-Inspired Approaches for Biomedical Applications

期刊

ACS OMEGA
卷 6, 期 1, 页码 46-54

出版社

AMER CHEMICAL SOC
DOI: 10.1021/acsomega.0c05275

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资金

  1. American Heart Association Transformational Project Award [19TPA34910111]
  2. University of Massachusetts Lowell start-up funds

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Modern biomedical applications require a combination of advanced technology and the adaptability of complex biosystems. Biomedical advancements inspired by origami have demonstrated voluminous structures, shape-shifting capabilities, and biocompatibility, offering promising potential for future discoveries. From tissue scaffolds to microfluidic devices, origami-inspired strategies have shown significant progress in various biomedical applications.
Modern day biomedical applications require progressions that combine advanced technology with the conformability of naturally occurring, complex biosystems. These advancements yield conformational interactions between the biomedical devices and the biological organisms' structures. Biomedical applications that adapt origami-inspired approaches have accrued aspired advances. Along with application-specific advantages, the most pertinent advances provided by origami-inspired strategies include voluminous structures with the ability to conform to biosystems, shape-shifting from two-dimensional (2D) to three-dimensional (3D) structures, and biocompatibility. Throughout this paper, the exploration of new studies, primarily within the past decade, with origami-based applications of biomedical devices, including their theories, experimental results, and plans for future testing are reviewed. This mini-review contains examples that aid the advancement of biomedical applications and hold promising future discoveries. The origami-inspired applications discussed within this paper are tissue scaffolds, drug delivery approaches, stents and catheters, implants, microfluidic devices, biosensors, and origami usage in surgery.

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