期刊
PLANTS-BASEL
卷 10, 期 1, 页码 -出版社
MDPI
DOI: 10.3390/plants10010080
关键词
sage; optimization; stirring and heating extraction; ultrasound-assisted extraction; mechanochemical extraction
资金
- Croatian Government through project CEKOM 3LJ [KK.01.2.2.03.0017]
- European Union (European Regional Development Fund-the Competitiveness and Cohesion Operational Programme) through project CEKOM 3LJ [KK.01.2.2.03.0017, KK.01.2.2.03]
Salvia officinalis L. is a good source of antioxidant compounds, with choline chloride: lactic acid found to be the most suitable solvent for extraction. Different extraction conditions were explored, demonstrating that deep eutectic solvents provided more efficient extraction of targeted compounds.
Salvia officinalis L. is a good source of antioxidant compounds such as phenolic diterpenes carnosic acid and carnosol. From 17 deep eutectic solvents (DESs) used, choline chloride: lactic acid (1:2 molar ratio) was found to be the most suitable for the extraction of targeted compounds. The influence of H2O content, extraction time, and temperature (for stirring and heating and for ultrasound-assisted extraction (UAE)), H2O content, extraction time, and vibration speed for mechanochemical extraction on the content of targeted compounds were investigated. Carnosic acid content obtained by the extraction assisted by stirring and heating was from 2.55 +/- 0.04 to 14.43 +/- 0.28 mu g mg(-1), for UAE it was from 1.62 +/- 0.29 to 14.00 +/- 0.02 mu g mg(-1), and for mechanochemical extraction the yield was from 1.80 +/- 0.02 to 8.26 +/- 0.45 mu g mg(-1). Determined carnosol content was in the range 0.81 +/- 0.01 to 4.83 +/- 0.09 mu g mg(-1) for the extraction with stirring and for UAE it was from 0.56 +/- 0.02 to 4.18 +/- 0.05 mu g mg(-1), and for mechanochemical extraction the yield was from 0.57 +/- 0.11 to 2.01 +/- 0.16 mu g mg(-1). Optimal extraction conditions determined by response surface methodology (RSM) were in accordance with experimentally demonstrated values. In comparison with previously published or own results using conventional solvents or supercritical CO2, used DES provided more efficient extraction of both targeted compounds.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据