期刊
METABOLITES
卷 10, 期 12, 页码 -出版社
MDPI
DOI: 10.3390/metabo10120508
关键词
selenium; selenium-enriched; Saccharomyces cerevisiae; probiotic yeast; hydrolysate; agro-industrial wastes; corn bran; soybean bran; bioreactor
资金
- Research Council for the State of Sao Paulo (Fundacao de Amparo a Pesquisa do Estado de Sao Paulo-FAPESP) [2016/10636-8]
- Coordination for the Improvement of Higher Education Personnel (Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior-USP-CAPES program)
- Council for Scientific and Technological Development (Conselho Nacional de Desenvolvimento Cientifico e Tecnologico-CNPq) [303943/2017-3]
The production of biomolecules using agro-industrial by-products as feedstock is a growing trend worldwide. Selenium (Se) is a trace element essential for health, and the Se-enrichment of yeast biomass can enhance its benefits. This study investigated the feasibility of the production of Saccharomyces cerevisiae Se-enriched biomass using a medium composed of corn bran and soybean bran acid hydrolysates as carbon and nitrogen sources in a stirred-tank reactor. After hydrolysis, hydrolysates presented complex composition and high concentrations of sugars, proteins, and minerals. The use of a stirred-tank bioreactor leads to the production of 9 g/L S. cerevisiae biomass enriched with 236.93 mu g/g Se, and 99% cell viability. Likewise, the combination of sugarcane molasses and soybean bran hydrolysate was effective for cell growth of a probiotic strain of S. cerevisiae with a 24.08% beta-glucan content. The results demonstrated that starchy acid hydrolysates are low-cost and efficient substrates for the production of yeast biomass and derivate products and may contribute to further studies for a sustainable development of biorefinery technologies.
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