相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。CD40 Agonist Antibodies in Cancer Immunotherapy
Robert H. Vonderheide
ANNUAL REVIEW OF MEDICINE, VOL 71, 2020 (2020)
IMMUNITY, HYPOXIA, AND METABOLISM-THE MENAGE A TROIS OF CANCER: IMPLICATIONS FOR IMMUNOTHERAPY
Carla Riera-Domingo et al.
PHYSIOLOGICAL REVIEWS (2020)
Cancer-Derived Succinate Promotes Macrophage Polarization and Cancer Metastasis via Succinate Receptor
Jing-Yiing Wu et al.
MOLECULAR CELL (2020)
Autophagy-dependent ferroptosis drives tumor-associated macrophage polarization via release and uptake of oncogenic KRAS protein
Enyong Dai et al.
AUTOPHAGY (2020)
Quantum dot-pulsed dendritic cell vaccines plus macrophage polarization for amplified cancer immunotherapy
Feng Liu et al.
BIOMATERIALS (2020)
TLR 7/8 agonist reverses oxaliplatin resistance in colorectal cancer via directing the myeloid-derived suppressor cells to tumoricidal M1-macrophages
Zhipeng Liu et al.
CANCER LETTERS (2020)
Lactic acid promotes macrophage polarization through MCT-HIF1α signaling in gastric cancer
Lan Zhang et al.
EXPERIMENTAL CELL RESEARCH (2020)
Detection of pancreatic ductal adenocarcinoma with galectin-9 serum levels
Adrian M. Seifert et al.
ONCOGENE (2020)
Nitric oxide orchestrates metabolic rewiring in M1 macrophages by targeting aconitase 2 and pyruvate dehydrogenase
Erika M. Palmieri et al.
NATURE COMMUNICATIONS (2020)
Interferon gamma inhibits CXCL8-CXCR2 axis mediated tumor-associated macrophages tumor trafficking and enhances anti-PD1 efficacy in pancreatic cancer
Mingjie Zhang et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2020)
Combined blockade of TGf-β1 and GM-CSF improves chemotherapeutic effects for pancreatic cancer by modulating tumor microenvironment
Qiaofei Liu et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2020)
Irreversible and sustained upregulation of endothelin axis during oncogene-associated pancreatic inflammation and cancer
Suprit Gupta et al.
NEOPLASIA (2020)
Remodeling tumor immune microenvironment via targeted blockade of PI3K-γ and CSF-1/CSF-1R pathways in tumor associated macrophages for pancreatic cancer therapy
Man Li et al.
JOURNAL OF CONTROLLED RELEASE (2020)
Metastasis-associated fibroblasts promote angiogenesis in metastasized pancreatic cancer via the CXCL8 and the CCL2 axes
Thomas M. Pausch et al.
SCIENTIFIC REPORTS (2020)
miR-128 Regulates Tumor Cell CD47 Expression and Promotes Anti-tumor Immunity in Pancreatic Cancer
Qing Xi et al.
FRONTIERS IN IMMUNOLOGY (2020)
Restoration of miR-340 controls pancreatic cancer cellCD47expression to promote macrophage phagocytosis and enhance antitumor immunity
Qing Xi et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2020)
Depletion of Macrophages Improves Therapeutic Response to Gemcitabine in Murine Pancreas Cancer
Soeren M. Buchholz et al.
CANCERS (2020)
VentX expression in tumor-associated macrophages promotes phagocytosis and immunity against pancreatic cancers
Yi Le et al.
JCI INSIGHT (2020)
Challenges and Opportunities for Pancreatic Cancer Immunotherapy
Adham S. Bear et al.
CANCER CELL (2020)
Tackling TAMs for Cancer Immunotherapy: It's Nano Time
Yishun Yang et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2020)
Macrophage-secreted MMP9 induces mesenchymal transition in pancreatic cancer cells via PAR1 activation
Cansu Tekin et al.
CELLULAR ONCOLOGY (2020)
Genome regulation by long noncoding RNA genes
H. Y. Chang
CANCER RESEARCH (2020)
Angiogenesis in pancreatic cancer: current research status and clinical implications
Shuo Li et al.
ANGIOGENESIS (2019)
Pomalidomide Alters Pancreatic Macrophage Populations to Generate an Immune-Responsive Environment at Precancerous and Cancerous Lesions
Ligia I. Bastea et al.
CANCER RESEARCH (2019)
Gut microbiota-stimulated cathepsin K secretion mediates TLR4-dependent M2 macrophage polarization and promotes tumor metastasis in colorectal cancer
Rui Li et al.
CELL DEATH AND DIFFERENTIATION (2019)
Macrophage-Released Pyrimidines Inhibit Gemcitabine Therapy in Pancreatic Cancer
Christopher J. Halbrook et al.
CELL METABOLISM (2019)
Early Detection of Pancreatic Cancer: Opportunities and Challenges
Aatur D. Singhi et al.
GASTROENTEROLOGY (2019)
GABRP regulates chemokine signalling, macrophage recruitment and tumour progression in pancreatic cancer through tuning KCNN4-mediated Ca2+ signalling in a GABA-independent manner
Shu-Heng Jiang et al.
GUT (2019)
Blocking Triggering Receptor Expressed on Myeloid Cells-1-Positive Tumor-Associated Macrophages Induced by Hypoxia Reverses Immunosuppression and Anti-Programmed Cell Death Ligand 1 Resistance in Liver Cancer
Qinchuan Wu et al.
HEPATOLOGY (2019)
Inflammation and Pancreatic Cancer: Focus on Metabolism, Cytokines, and Immunity
Andrea Padoan et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Hes1 plays an essential role in Kras-driven pancreatic tumorigenesis
Yoshihiro Nishikawa et al.
ONCOGENE (2019)
Hypoxia-induced tumor exosomes promote M2-like macrophage polarization of infiltrating myeloid cells and microRNA-mediated metabolic shift
Jung Eun Park et al.
ONCOGENE (2019)
Cooperatively Responsive Peptide Nanotherapeutic that Regulates Angiopoietin Receptor Tie2 Activity in Tumor Microenvironment To Prevent Breast Tumor Relapse after Chemotherapy
Lijing Zhang et al.
ACS NANO (2019)
TAMing pancreatic cancer: combat with a double edged sword
Manendra Babu Lankadasari et al.
MOLECULAR CANCER (2019)
The microbiota and microbiome in pancreatic cancer: more influential than expected
Miao-Yan Wei et al.
MOLECULAR CANCER (2019)
Tumor-associated macrophage-secreted 14-3-3ζ signals via AXL to promote pancreatic cancer chemoresistance
Gabriele D'Errico et al.
ONCOGENE (2019)
MST1R kinase accelerates pancreatic cancer progression via effects on both epithelial cells and macrophages
Michele L. Babicky et al.
ONCOGENE (2019)
Intravenous delivery of the toll-like receptor 7 agonist SC1 confers tumor control by inducing a CD8+T cell response
Fulvia Vascotto et al.
ONCOIMMUNOLOGY (2019)
Inhibition of murine hepatoma tumor growth by cryptotanshinone involves TLR7-dependent activation of macrophages and induction of adaptive antitumor immune defenses
Zhen Han et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2019)
Dynamic gene regulation by nuclear colony-stimulating factor 1 receptor in human monocytes and macrophages
Laura Bencheikh et al.
NATURE COMMUNICATIONS (2019)
DNA released from neutrophil extracellular traps (NETs) activates pancreatic stellate cells and enhances pancreatic tumor growth
Jennifer L. Miller-Ocuin et al.
ONCOIMMUNOLOGY (2019)
Lyophilizable and Multifaceted Toll-like Receptor 7/8 Agonist-Loaded Nanoemulsion for the Reprogramming of Tumor Microenvironments and Enhanced Cancer Immunotherapy
Sun-Young Kim et al.
ACS NANO (2019)
Tumour cell-derived debris and IgG synergistically promote metastasis of pancreatic cancer by inducing inflammation via tumour-associated macrophages
Qi Chen et al.
BRITISH JOURNAL OF CANCER (2019)
Single-cell RNA sequencing reveals compartmental remodeling of tumor-infiltrating immune cells induced by anti-CD47 targeting in pancreatic cancer
Yu Pan et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2019)
Epithelial-Stromal Interactions in Pancreatic Cancer
Yaqing Zhang et al.
ANNUAL REVIEW OF PHYSIOLOGY, VOL 81 (2019)
The Pleiotropic Effects of the GM-CSF Rheostat on Myeloid Cell Differentiation and Function: More Than a Numbers Game
Yifan Zhan et al.
FRONTIERS IN IMMUNOLOGY (2019)
INT-HA induces M2-like macrophage differentiation of human monocytes via TLR4-miR-935 pathway
Boke Zhang et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2019)
Molecular insight of regorafenib treatment for colorectal cancer
Hiroyuki Arai et al.
CANCER TREATMENT REVIEWS (2019)
Galactan isolated from Cantharellus cibarius modulates antitumor immune response by converting tumor-associated macrophages toward M1-like phenotype
Yue Meng et al.
CARBOHYDRATE POLYMERS (2019)
被撤回的出版物: Resistin effects on pancreatic cancer progression and chemoresistance are mediated through its receptors CAP1 and TLR4 (Retracted article. See vol. 237, pg. 1632, 2022)
Min Zhang et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2019)
IL-6 Signaling Blockade during CD40-Mediated Immune Activation Favors Antitumor Factors by Reducing TGF-β, Collagen Type I, and PD-L1/PD-1
Emma Eriksson et al.
JOURNAL OF IMMUNOLOGY (2019)
Metabolic rewiring of macrophages by CpG potentiates clearance of cancer cells and overcomes tumor-expressed CD47-mediated 'don't-eat-me' signal
Mingen Liu et al.
NATURE IMMUNOLOGY (2019)
Endothelial-mesenchymal transition harnesses HSP90α-secreting M2-macrophages to exacerbate pancreatic ductal adenocarcinoma
Chi-Shuan Fan et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2019)
Macrophages in the microenvironment of head and neck cancer: potential targets for cancer therapy
Diane Evrard et al.
ORAL ONCOLOGY (2019)
Role of the microbiome in occurrence, development and treatment of pancreatic cancer
Yicheng Wang et al.
MOLECULAR CANCER (2019)
Depletion of activated macrophages with a folate receptor-beta-specific antibody improves symptoms in mouse models of rheumatoid arthritis
Yingwen Hu et al.
ARTHRITIS RESEARCH & THERAPY (2019)
Hypoxia as a barrier to immunotherapy in pancreatic adenocarcinoma
S. K. Daniel et al.
CLINICAL AND TRANSLATIONAL MEDICINE (2019)
The roles of CSFs on the functional polarization of tumor-associated macrophages
Pascale Jeannin et al.
FEBS JOURNAL (2018)
Advances in the understanding and treatment of sepsis-induced immunosuppression
Fabienne Venet et al.
NATURE REVIEWS NEPHROLOGY (2018)
Depletion of tumor-associated macrophages switches the epigenetic profile of pancreatic cancer infiltrating T cells and restores their anti-tumor phenotype
Simone Borgoni et al.
ONCOIMMUNOLOGY (2018)
The dual effects of a novel peptibody on angiogenesis inhibition and M2 macrophage polarization on sarcoma
Xiaoqing Zhu et al.
CANCER LETTERS (2018)
DAMP-TLR-cytokine axis dictates the fate of tumor
Ashok Patidar et al.
CYTOKINE (2018)
The role of inflammatory cytokines and tumor associated macrophages (TAMs) in microenvironment of pancreatic cancer
Saeed Farajzadeh Valilou et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2018)
Regular Use of Aspirin or Non-Aspirin Nonsteroidal Anti-Inflammatory Drugs Is Not Associated With Risk of Incident Pancreatic Cancer in Two Large Cohort Studies
Natalia Khalaf et al.
GASTROENTEROLOGY (2018)
Hypoxia-inducible factor-1/interleukin-1 signaling enhances hepatoma epithelial-mesenchymal transition through macrophages in a hypoxic-inflammatory microenvironment
Jingying Zhang et al.
HEPATOLOGY (2018)
Effective cancer immunotherapy based on combination of TLR agonists with stimulation of phagocytosis
Veronika Caisova et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2018)
KRAS mutation and epithelial-macrophage interplay in pancreatic neoplastic transformation
Faraz Bishehsari et al.
INTERNATIONAL JOURNAL OF CANCER (2018)
Blocking Interleukin (IL)4-and IL13-Mediated Phosphorylation of STAT6 (Tyr641) Decreases M2 Polarization of Macrophages and Protects Against Macrophage-Mediated Radioresistance of Inflammatory Breast Cancer
Omar M. Rahal et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2018)
Tumor-secreted Pros1 inhibits macrophage M1 polarization to reduce antitumor immune response
Eric Ubil et al.
JOURNAL OF CLINICAL INVESTIGATION (2018)
Macrophage-Associated PGK1 Phosphorylation Promotes Aerobic Glycolysis and Tumorigenesis
Yajuan Zhang et al.
MOLECULAR CELL (2018)
Polymer-Mediated Inhibition of Pro-invasive Nucleic Acid DAMPs and Microvesicles Limits Pancreatic Cancer Metastasis
Ibtehaj Naqvi et al.
MOLECULAR THERAPY (2018)
GM-CSF improves the immune response to the diphtheria-component in a multivalent vaccine
Marco Grasse et al.
VACCINE (2018)
Tumor-associated macrophages promote progression and the Warburg effect via CCL18/NF-kB/VCAM-1 pathway in pancreatic ductal adenocarcinoma
Huilin Ye et al.
CELL DEATH & DISEASE (2018)
Overexpression of Tie2 is associated with poor prognosis in patients with gastric cancer
Wei-Jun Yang et al.
ONCOLOGY LETTERS (2018)
The homeobox protein VentX reverts immune suppression in the tumor microenvironment
Yi Le et al.
NATURE COMMUNICATIONS (2018)
Vascular niche IL-6 induces alternative macrophage activation in glioblastoma through HIF-2 alpha
Qirui Wang et al.
NATURE COMMUNICATIONS (2018)
IL-34 and CSF-1 display an equivalent macrophage differentiation ability but a different polarization potential
Sonia Boulakirba et al.
SCIENTIFIC REPORTS (2018)
CSF1R+ Macrophages Sustain Pancreatic Tumor Growth through T Cell Suppression and Maintenance of Key Gene Programs that Define the Squamous Subtype
Juliana B. Candido et al.
CELL REPORTS (2018)
Pancreatic Ductal Adenocarcinoma: A Strong imbalance of Good and Bad immunological Cops in the Tumor Microenvironment
Etienne D. Foucher et al.
FRONTIERS IN IMMUNOLOGY (2018)
Breast Cancer-Derived Exosomes Alter Macrophage Polarization via gp130/STAT3 Signaling
Sunyoung Ham et al.
FRONTIERS IN IMMUNOLOGY (2018)
Snail-overexpressing Cancer Cells Promote M2-Like Polarization of Tumor-Associated Macrophages by Delivering MiR-21-Abundant Exosomes
Chia-Hsin Hsieh et al.
NEOPLASIA (2018)
Myeloid-derived macrophages and secreted HSP90α induce pancreatic ductal adenocarcinoma development
Chia-Chi Chen et al.
ONCOIMMUNOLOGY (2018)
Immune Evasion in Pancreatic Cancer: From Mechanisms to Therapy
Neus Martinez-Bosch et al.
CANCERS (2018)
Prognostic Role of Hypoxia-Inducible Factor-2α Tumor Cell Expression in Cancer Patients: A Meta-Analysis
Eloy Moreno Roig et al.
FRONTIERS IN ONCOLOGY (2018)
TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy
Christopher B. Rodell et al.
NATURE BIOMEDICAL ENGINEERING (2018)
Exosomes derived from hypoxic epithelial ovarian cancer cells deliver microRNAs to macrophages and elicit a tumor-promoted phenotype
Xin Chen et al.
CANCER LETTERS (2018)
Nrf2 activation drive macrophages polarization and cancer cell epithelial-mesenchymal transition during interaction
Rui Feng et al.
CELL COMMUNICATION AND SIGNALING (2018)
Interleukin-1 Beta-A Friend or Foe in Malignancies?
Rebekka Bent et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Immunoengineering through cancer vaccines - A personalized and multi-step vaccine approach towards precise cancer immunity
Lien Lybaert et al.
JOURNAL OF CONTROLLED RELEASE (2018)
Tumor microenvironment participates in metastasis of pancreatic cancer
Bo Ren et al.
MOLECULAR CANCER (2018)
Low dose radiation primed iNOS+M1macrophages modulate angiogenic programming of tumor derived endothelium
Vinod Nadella et al.
MOLECULAR CARCINOGENESIS (2018)
Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1
Evanna L. Mills et al.
NATURE (2018)
Gemcitabine treatment promotes immunosuppressive microenvironment in pancreatic tumors by supporting the infiltration, growth, and polarization of macrophages
Sachin Kumar Deshmukh et al.
SCIENTIFIC REPORTS (2018)
Toll-like receptors 2, 4 and 9 and hypoxia markers HIF-1alpha and CAIX in pancreatic intraepithelial neoplasia
Joni Leppanen et al.
APMIS (2018)
RIP1 Kinase Drives Macrophage-Mediated Adaptive Immune Tolerance in Pancreatic Cancer
Wei Wang et al.
CANCER CELL (2018)
Radiation combined with macrophage depletion promotes adaptive immunity and potentiates checkpoint blockade
Keaton I. Jones et al.
EMBO MOLECULAR MEDICINE (2018)
Serum levels of IL-6, IL-8, and IL-10 are indicators of prognosis in pancreatic cancer
Lanyun Feng et al.
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH (2018)
Tumor-promoting effects of pancreatic cancer cell exosomes on THP-1-derived macrophages
Samuel S. Linton et al.
PLOS ONE (2018)
Tumor-driven like macrophages induced by conditioned media from pancreatic ductal adenocarcinoma promote tumor metastasis via secreting IL-8
Shao-jie Chen et al.
CANCER MEDICINE (2018)
Tumor cell-released autophagosomes (TRAPs) promote immunosuppression through induction of M2-like macrophages with increased expression of PD-L1
Zhi-Fa Wen et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2018)
Targeting myeloid-inflamed tumor with anti-CSF-1R antibody expands CD137+effector T-cells in the murine model of pancreatic cancer
May Tun Saung et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2018)
Molecular mechanisms of IL-33-mediated stromal interactions in cancer metastasis
Patrik Andersson et al.
JCI INSIGHT (2018)
Immunotherapy and Prevention of Pancreatic Cancer
Alexander H. Morrison et al.
TRENDS IN CANCER (2018)
Pancreatic cancer therapy with combined mesothelin-redirected chimeric antigen receptor T cells and cytokine-armed oncolytic adenoviruses
Keisuke Watanabe et al.
JCI INSIGHT (2018)
IFNγ: signalling, epigenetics and roles in immunity, metabolism, disease and cancer immunotherapy
Lionel B. Ivashkiv
NATURE REVIEWS IMMUNOLOGY (2018)
T-cell programming in pancreatic adenocarcinoma: a review
Y. D. Seo et al.
CANCER GENE THERAPY (2017)
Constitutive IRAK4 Activation Underlies Poor Prognosis and Chemoresistance in Pancreatic Ductal Adenocarcinoma
Daoxiang Zhang et al.
CLINICAL CANCER RESEARCH (2017)
Myeloid cells are required for PD-1/PD-L1 checkpoint activation and the establishment of an immunosuppressive environment in pancreatic cancer
Yaqing Zhang et al.
GUT (2017)
Pharmacological macrophage inhibition decreases metastasis formation in a genetic model of pancreatic cancer
Heidi Griesmann et al.
GUT (2017)
Tissue-Resident Macrophages in Pancreatic Ductal Adenocarcinoma Originate from Embryonic Hematopoiesis and Promote Tumor Progression
Yu Zhu et al.
IMMUNITY (2017)
Recent progress in GM-CSF-based cancer immunotherapy
Wan-Lun Yan et al.
IMMUNOTHERAPY (2017)
Optimized biodegradable polymeric reservoir-mediated local and sustained co-delivery of dendritic cells and oncolytic adenovirus co-expressing IL-12 and GM-CSF for cancer immunotherapy
Eonju Oh et al.
JOURNAL OF CONTROLLED RELEASE (2017)
Vaccination with poly (IC: LC) and peptide-pulsed autologous dendritic cells in patients with pancreatic cancer
Shikhar Mehrotra et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2017)
The role of stromal cancer-associated fibroblasts in pancreatic cancer
Dagny von Ahrens et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2017)
Neoadjuvant chemoradiotherapy of pancreatic cancer induces a favorable immunogenic tumor microenvironment associated with increased major histocompatibility complex class I-related chain A/B expression
Takashi Murakami et al.
JOURNAL OF SURGICAL ONCOLOGY (2017)
Macrophages as Key Drivers of Cancer Progression and Metastasis
Sebastian R. Nielsen et al.
MEDIATORS OF INFLAMMATION (2017)
The Selective Tie2 Inhibitor Rebastinib Blocks Recruitment and Function of Tie2Hi Macrophages in Breast Cancer and Pancreatic Neuroendocrine Tumors
Allison S. Harney et al.
MOLECULAR CANCER THERAPEUTICS (2017)
Novel TREM-1 Inhibitors Attenuate Tumor Growth and Prolong Survival in Experimental Pancreatic Cancer
Zu T. Shen et al.
MOLECULAR PHARMACEUTICS (2017)
Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer
Sushrut Kamerkar et al.
NATURE (2017)
Glucose feeds the TCA cycle via circulating lactate
Sheng Hui et al.
NATURE (2017)
PD-1 expression by tumour-associated macrophages inhibits phagocytosis and tumour immunity
Sydney R. Gordon et al.
NATURE (2017)
Dectin 1 activation on macrophages by galectin 9 promotes pancreatic carcinoma and peritumoral immune tolerance
Donnele Daley et al.
NATURE MEDICINE (2017)
Tumour-associated macrophages as treatment targets in oncology
Alberto Mantovani et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2017)
Acinar cell plasticity and development of pancreatic ductal adenocarcinoma
Peter Storz
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2017)
TEMs but not DKK1 could serve as complementary biomarkers for AFP in diagnosing AFP-negative hepatocellular carcinoma
Liping Mao et al.
PLOS ONE (2017)
High toll-like receptor (TLR) 9 expression is associated with better prognosis in surgically treated pancreatic cancer patients
Joni Leppanen et al.
VIRCHOWS ARCHIV (2017)
Mitochondrial dynamics controls anti-tumour innate immunity by regulating CHIP-IRF1 axis stability
Zhengjun Gao et al.
NATURE COMMUNICATIONS (2017)
The Presence of Interleukin-13 at Pancreatic ADM/PanIN Lesions Alters Macrophage Populations and Mediates Pancreatic Tumorigenesis
Geou-Yarh Liou et al.
CELL REPORTS (2017)
Colony-stimulating factor 1 receptor (CSF1R) inhibitors in cancer therapy
Michael A. Cannarile et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2017)
Therapeutic potential of carbohydrates as regulators of macrophage activation
Mimmi L. E. Lundahl et al.
BIOCHEMICAL PHARMACOLOGY (2017)
Interleukin 6 induces M2 macrophage differentiation by STAT3 activation that correlates with gastric cancer progression
Xiao-Long Fu et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2017)
Cancer-Associated Fibroblasts Neutralize the Anti-tumor Effect of CSF1 Receptor Blockade by Inducing PMN-MDSC Infiltration of Tumors
Vinit Kumar et al.
CANCER CELL (2017)
α-ketoglutarate orchestrates macrophage activation through metabolic and epigenetic reprogramming
Pu-Ste Liu et al.
NATURE IMMUNOLOGY (2017)
Cancer cell and macrophage cross-talk in the tumor microenvironment
Nathalie Dehnel et al.
CURRENT OPINION IN PHARMACOLOGY (2017)
M2-like macrophage polarization in high lactic acid-producing head and neck cancer
Toshimitsu Ohashi et al.
CANCER SCIENCE (2017)
Cellular and Molecular Identity of Tumor-Associated Macrophages in Glioblastoma
Zhihong Chen et al.
CANCER RESEARCH (2017)
Diabetes, Pancreatogenic Diabetes, and Pancreatic Cancer
Dana K. Andersen et al.
DIABETES (2017)
Obstacles Posed by the Tumor Microenvironment to T cell Activity: A Case for Synergistic Therapies
Kristin G. Anderson et al.
CANCER CELL (2017)
Simvastatin attenuates macrophage-mediated gemcitabine resistance of pancreatic ductal adenocarcinoma by regulating the TGF-β1/Gfi-1 axis
Guozhe Xian et al.
CANCER LETTERS (2017)
M-CSF and GM-CSF Receptor Signaling Differentially Regulate Monocyte Maturation and Macrophage Polarization in the Tumor Microenvironment
Eva Van Overmeire et al.
CANCER RESEARCH (2016)
Overcoming HBV immune tolerance to eliminate HBsAg-positive hepatocytes via pre-administration of GM-CSF as a novel adjuvant for a hepatitis B vaccine in HBV transgenic mice
Xianzheng Wang et al.
CELLULAR & MOLECULAR IMMUNOLOGY (2016)
TLR7 and TLR9 ligands regulate antigen presentation by macrophages
Teja Celhar et al.
INTERNATIONAL IMMUNOLOGY (2016)
The pancreatic cancer secreted REG4 promotes macrophage polarization to M2 through EGFR/AKT/CREB pathway
Xiuying Ma et al.
ONCOLOGY REPORTS (2016)
Bruton Tyrosine Kinase-Dependent Immune Cell Cross-talk Drives Pancreas Cancer
Andrew J. Gunderson et al.
CANCER DISCOVERY (2016)
Extracellular Vesicles in Cancer: Cell-to-Cell Mediators of Metastasis
Annette Becker et al.
CANCER CELL (2016)
Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation
Vicky Lampropoulou et al.
CELL METABOLISM (2016)
Lurbinectedin induces depletion of tumor-associated macrophages, an essential component of its in vivo synergism with gemcitabine, in pancreatic adenocarcinoma mouse models
Maria Virtudes Cespedes et al.
DISEASE MODELS & MECHANISMS (2016)
YAP1 and TAZ Control Pancreatic Cancer Initiation in Mice by Direct Up-regulation of JAK-STAT3 Signaling
Ralph Gruber et al.
GASTROENTEROLOGY (2016)
Tissue-Resident Macrophage Ontogeny and Homeostasis
Florent Ginhoux et al.
IMMUNITY (2016)
Atorvastatin (Lipitor) attenuates the effects of aspirin on pancreatic cancerogenesis and the chemotherapeutic efficacy of gemcitabine on pancreatic cancer by promoting M2 polarized tumor associated macrophages
Qiaofei Liu et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2016)
Macrophage-secreted granulin supports pancreatic cancer metastasis by inducing liver fibrosis
Sebastian R. Nielsen et al.
NATURE CELL BIOLOGY (2016)
New insights into the multidimensional concept of macrophage ontogeny, activation and function
Florent Ginhoux et al.
NATURE IMMUNOLOGY (2016)
Novel MET/TIE2/VEGFR2 inhibitor altiratinib inhibits tumor growth and invasiveness in bevacizumab-resistant glioblastoma mouse models
Yuji Piao et al.
NEURO-ONCOLOGY (2016)
Macrophage PI3Kγ Drives Pancreatic Ductal Adenocarcinoma Progression
Megan M. Kaneda et al.
CANCER DISCOVERY (2016)
IFNγ and CCL2 Cooperate to Redirect Tumor-Infiltrating Monocytes to Degrade Fibrosis and Enhance Chemotherapy Efficacy in Pancreatic Carcinoma
Kristen B. Long et al.
CANCER DISCOVERY (2016)
Targeting tumor-associated macrophages to combat pancreatic cancer
Ran Cui et al.
ONCOTARGET (2016)
Pancreatic Cancer Cell Exosome-Mediated Macrophage Reprogramming and the Role of MicroRNAs 155 and 125b2 Transfection using Nanoparticle Delivery Systems
Mei-Ju Su et al.
SCIENTIFIC REPORTS (2016)
CD14/TLR4 priming potentially recalibrates and exerts anti-tumor efficacy in tumor associated macrophages in a mouse model of pancreatic carcinoma
Hridayesh Prakash et al.
SCIENTIFIC REPORTS (2016)
Plasma Levels and Diagnostic Utility of Macrophage Colony-Stimulating Factor, Matrix Metalloproteinase-9, and Tissue Inhibitor of Metalloproteinases-1 as New Biomarkers of Breast Cancer
Slawomir Lawicki et al.
ANNALS OF LABORATORY MEDICINE (2016)
Warburg metabolism in tumor-conditioned macrophages promotes metastasis in human pancreatic ductal adenocarcinoma
Hweixian Leong Penny et al.
ONCOIMMUNOLOGY (2016)
Hypoxia Inducible Factor 1 (HIF-1) Recruits Macrophage to Activate Pancreatic Stellate Cells in Pancreatic Ductal Adenocarcinoma
Na Li et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)
Toll Like Receptor 2, 4, and 9 Signaling Promotes Autoregulative Tumor Cell Growth and VEGF/PDGF Expression in Human Pancreatic Cancer
Tanja Grimmig et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)
Perivascular M2 Macrophages Stimulate Tumor Relapse after Chemotherapy
Russell Hughes et al.
CANCER RESEARCH (2015)
Targeting the LOX/hypoxia axis reverses many of the features that make pancreatic cancer deadly: inhibition of LOX abrogates metastasis and enhances drug efficacy
Bryan W. Miller et al.
EMBO MOLECULAR MEDICINE (2015)
TLR7 and TLR8 expression increases tumor cell proliferation and promotes chemoresistance in human pancreatic cancer
Tanja Grimmig et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2015)
The Combination of ISCOMATRIX Adjuvant and TLR Agonists Induces Regression of Established Solid Tumors In Vivo
Anabel Silva et al.
JOURNAL OF IMMUNOLOGY (2015)
Glypican-1 identifies cancer exosomes and detects early pancreatic cancer
Sonia A. Melo et al.
NATURE (2015)
Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver
Bruno Costa-Silva et al.
NATURE CELL BIOLOGY (2015)
CD14-expressing cancer cells establish the inflammatory and proliferative tumor microenvironment in bladder cancer
Ming T. Cheah et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Alternatively activated macrophages promote pancreatic fibrosis in chronic pancreatitis
Jing Xue et al.
NATURE COMMUNICATIONS (2015)
被撤回的出版物: Chronic alcohol exposure exacerbates inflammation and triggers pancreatic acinar-to-ductal metaplasia through PI3K/Akt/IKK (Retracted article. See vol. 52, pg. 82, 2023)
Xin Huang et al.
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2015)
CCL18 promotes epithelial-mesenchymal transition, invasion and migration of pancreatic cancer cells in pancreatic ductal adenocarcinoma
Fanbin Meng et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2015)
CUX1 modulates polarization of tumor-associated macrophages by antagonizing NF-κB signaling
B. Kuehnemuth et al.
ONCOGENE (2015)
Smoking accelerates pancreatic cancer progression by promoting differentiation of MDSCs and inducing HB-EGF expression in macrophages
S. Kumar et al.
ONCOGENE (2015)
Targeting Tumor-Associated Macrophages with Anti-CSF-1R Antibody Reveals a Strategy for Cancer Therapy
Carola H. Ries et al.
CANCER CELL (2014)
Tumour-educated macrophages display a mixed polarisation and enhance pancreatic cancer cell invasion
Emelie Karnevi et al.
IMMUNOLOGY AND CELL BIOLOGY (2014)
Tumor-associated macrophages exhibit pro- and anti-inflammatory properties by which they impact on pancreatic tumorigenesis
Ole Helm et al.
INTERNATIONAL JOURNAL OF CANCER (2014)
Cancer-related inflammation and treatment effectiveness
Connie I. Diakos et al.
LANCET ONCOLOGY (2014)
Anti-inflammatory macrophages activate invasion in pancreatic adenocarcinoma by increasing the MMP9 and ADAM8 expression
Pauli Puolakkainen et al.
MEDICAL ONCOLOGY (2014)
The Yin and Yang of Toll-like receptors in cancer
J-P Pradere et al.
ONCOGENE (2014)
Role of Angiopoietin-2 in Adaptive Tumor Resistance to VEGF Signaling Blockade
Nicolo Rigamonti et al.
CELL REPORTS (2014)
Role of Macrophage Targeting in the Antitumor Activity of Trabectedin
Giovanni Germano et al.
CANCER CELL (2013)
TIE2-expressing monocytes as a diagnostic marker for hepatocellular carcinoma correlates with angiogenesis
Tokuhiro Matsubara et al.
HEPATOLOGY (2013)
Macrophage-secreted cytokines drive pancreatic acinar-to-ductal metaplasia through NF-κB and MMPs
Geou-Yarh Liou et al.
JOURNAL OF CELL BIOLOGY (2013)
Macrophage Scavenger Receptor A Promotes Tumor Progression in Murine Models of Ovarian and Pancreatic Cancer
Claudine Neyen et al.
JOURNAL OF IMMUNOLOGY (2013)
M2-polarized tumor-associated macrophages promoted epithelial-mesenchymal transition in pancreatic cancer cells, partially through TLR4/IL-10 signaling pathway
Chao-Ying Liu et al.
LABORATORY INVESTIGATION (2013)
CSF-1R inhibition alters macrophage polarization and blocks glioma progression
Stephanie M. Pyonteck et al.
NATURE MEDICINE (2013)
REG3β contributes to the immunosuppressive microenvironment of pancreatic cancer
Emma Folch-Puy
ONCOIMMUNOLOGY (2013)
Clinical Significance of Folate Receptor β-expressing Tumor-associated Macrophages in Pancreatic Cancer
Hiroshi Kurahara et al.
ANNALS OF SURGICAL ONCOLOGY (2012)
Role of c-MYC in alternative activation of human macrophages and tumor-associated macrophage biology
Oscar M. Pello et al.
BLOOD (2012)
Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy
Gregg L. Semenza
TRENDS IN PHARMACOLOGICAL SCIENCES (2012)
CD40 Agonists Alter Tumor Stroma and Show Efficacy Against Pancreatic Carcinoma in Mice and Humans
Gregory L. Beatty et al.
SCIENCE (2011)
CXCL8/IL-8 and CXCL12/SDF-1α co-operatively promote invasiveness and angiogenesis in pancreatic cancer
Yoichi Matsuo et al.
INTERNATIONAL JOURNAL OF CANCER (2009)
Discovery of a cytokine and its receptor by functional screening of the extracellular proteome
Haishan Lin et al.
SCIENCE (2008)
Opposite immune functions of GM-CSF administered as vaccine adjuvant in cancer patients
G. Parmiani et al.
ANNALS OF ONCOLOGY (2007)