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Microvesicles containing miRNAs promote muscle cell death in cancer cachexia via TLR7
Wei A. He et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Attenuation of muscle wasting in murine C2C12 myotubes by epigallocatechin-3-gallate
Kamran A. Mirza et al.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE (2014)
Psychosocial impact of cancer cachexia
Jane B. Hopkinson
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE (2014)
Glycyrrhizin, inhibitor of high mobility group box-1, attenuates monocrotaline-induced pulmonary hypertension and vascular remodeling in rats
Pil-Sung Yang et al.
RESPIRATORY RESEARCH (2014)
Cancer cachexia: understanding the molecular basis
Josep M. Argiles et al.
NATURE REVIEWS CANCER (2014)
The influence of skeletal muscle on systemic aging and lifespan
Fabio Demontis et al.
AGING CELL (2013)
Autophagic Degradation Contributes to Muscle Wasting in Cancer Cachexia
Fabio Penna et al.
AMERICAN JOURNAL OF PATHOLOGY (2013)
The effect of eicosapentaenoic and docosahexaenoic acid on protein synthesis and breakdown in murine C2C12 myotubes
Torkamol Kamolrat et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2013)
Omega-3 polyunsaturated fatty acid has an anti-oxidant effect via the Nrf-2/HO-1 pathway in 3T3-L1 adipocytes
Chisato Kusunoki et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2013)
Ursolic acid in cancer prevention and treatment: Molecular targets, pharmacokinetics and clinical studies
Muthu K. Shanmugam et al.
BIOCHEMICAL PHARMACOLOGY (2013)
Cancer-induced anorexia in tumor-bearing mice is dependent on cyclooxygenase-1
Johan Ruud et al.
BRAIN BEHAVIOR AND IMMUNITY (2013)
Exercise Metabolism and the Molecular Regulation of Skeletal Muscle Adaptation
Brendan Egan et al.
CELL METABOLISM (2013)
Green tea polyphenol epigallocatechin-3-gallate (EGCG) as adjuvant in cancer therapy
Elena Lecumberri et al.
CLINICAL NUTRITION (2013)
Polyphenols prevent ageing-related impairment in skeletal muscle mitochondrial function through decreased reactive oxygen species production
Anne-Laure Charles et al.
EXPERIMENTAL PHYSIOLOGY (2013)
Diaphragm and ventilatory dysfunction during cancer cachexia
Brandon M. Roberts et al.
FASEB JOURNAL (2013)
Muscle type and fiber type specificity in muscle wasting
Stefano Ciciliot et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2013)
The Role of Metallothionein in Oxidative Stress
Branislav Ruttkay-Nedecky et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2013)
SIRT1 Protein, by Blocking the Activities of Transcription Factors FoxO1 and FoxO3, Inhibits Muscle Atrophy and Promotes Muscle Growth
Donghoon Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Resveratrol promotes myogenesis and hypertrophy in murine myoblasts
Anna Montesano et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2013)
LOSS OF SPARC IN MOUSE SKELETAL MUSCLE CAUSES MYOFIBER ATROPHY
Katsuyuki Nakamura et al.
MUSCLE & NERVE (2013)
Influence of a nutritional intervention on dietary intake and quality of life in cancer patients: A randomized controlled trial
Alexandra Uster et al.
NUTRITION (2013)
Effects of Resveratrol on the Recovery of Muscle Mass Following Disuse in the Plantaris Muscle of Aged Rats
Brian T. Bennett et al.
PLOS ONE (2013)
Progressive resistance training rebuilds lean body mass in head and neck cancer patients after radiotherapy - Results from the randomized DAHANCA 25B trial
Simon Lonbro et al.
RADIOTHERAPY AND ONCOLOGY (2013)
DHA Inhibits Protein Degradation More Efficiently than EPA by Regulating the PPARγ/NFκB Pathway in C2C12 Myotubes
Yue Wang et al.
BIOMED RESEARCH INTERNATIONAL (2013)
Cancer cachexia prevention via physical exercise: molecular mechanisms
Douglas W. Gould et al.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE (2013)
Gut barrier dysfunction and microbial translocation in cancer cachexia: a new therapeutic target
Gerald L. Klein et al.
CURRENT OPINION IN SUPPORTIVE AND PALLIATIVE CARE (2013)
Myostatin inhibitors as therapies for muscle wasting associated with cancer and other disorders
Rosamund C. Smith et al.
CURRENT OPINION IN SUPPORTIVE AND PALLIATIVE CARE (2013)
Prevention and Treatment of Colorectal Cancer by Natural Agents from Mother Nature
Bharat Aggarwal et al.
CURRENT COLORECTAL CANCER REPORTS (2013)
Resveratrol prevents dexamethasone-induced expression of the muscle atrophy-related ubiquitin ligases atrogin-1 and MuRF1 in cultured myotubes through a SIRT1-dependent mechanism
Nima Alamdari et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2012)
Urinary biomarkers of oxidative status
Dora Il'yasova et al.
CLINICA CHIMICA ACTA (2012)
TWEAK and TRAF6 regulate skeletal muscle atrophy
Ashok Kumar et al.
CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE (2012)
The p97/VCP ATPase is critical in muscle atrophy and the accelerated degradation of muscle proteins
Rosanna Piccirillo et al.
EMBO JOURNAL (2012)
Alkaloids Isolated from Natural Herbs as the Anticancer Agents
Jin-Jian Lu et al.
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE (2012)
Insulin Resistance and Cancer Risk: An Overview of the Pathogenetic Mechanisms
Biagio Arcidiacono et al.
EXPERIMENTAL DIABETES RESEARCH (2012)
Oral Rg1 supplementation strengthens antioxidant defense system against exercise-induced oxidative stress in rat skeletal muscles
Szu-Hsien Yu et al.
JOURNAL OF THE INTERNATIONAL SOCIETY OF SPORTS NUTRITION (2012)
Oral Nutritional Interventions in Malnourished Patients With Cancer: A Systematic Review and Meta-Analysis
Christine Baldwin et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2012)
A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis
Pontus Bostroem et al.
NATURE (2012)
Theophylline is able to partially revert cachexia in tumour-bearing rats
Mireia Olivan et al.
NUTRITION & METABOLISM (2012)
Reduction of oxidative stress in liver cancer patients by oral green tea polyphenol tablets during hepatic arterial infusion chemotherapy
Yasutaka Baba et al.
EXPERIMENTAL AND THERAPEUTIC MEDICINE (2012)
The effect of exercise on IL-6-induced cachexia in the ApcMin/+ mouse
Melissa J. Puppa et al.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE (2012)
IL-6 regulation on skeletal muscle mitochondrial remodeling during cancer cachexia in the Apc>Min mouse
James P. White et al.
SKELETAL MUSCLE (2012)
TRAF6 coordinates the activation of autophagy and ubiquitin-proteasome systems in atrophying skeletal muscle
Pradyut K. Paul et al.
AUTOPHAGY (2011)
Inhibition of tumor growth by quercetin with increase of survival and prevention of cachexia in Walker 256 tumor-bearing rats
Camila A. Camargo et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
Influence of eicosapentaenoic acid supplementation on lean body mass in cancer cachexia
R. A. Murphy et al.
BRITISH JOURNAL OF CANCER (2011)
EPA inhibits the inhibitor of κBα (IκBα)/NF-κB/muscle RING finger 1 pathway in C2C12 myotubes in a PPARγ-dependent manner
Feiruo Huang et al.
BRITISH JOURNAL OF NUTRITION (2011)
Epigallocatechin-3-gallate effectively attenuates skeletal muscle atrophy caused by cancer cachexia
Hang Wang et al.
CANCER LETTERS (2011)
The SCF-Fbxo40 Complex Induces IRS1 Ubiquitination in Skeletal Muscle, Limiting IGF1 Signaling
Jun Shi et al.
DEVELOPMENTAL CELL (2011)
Clinical Outcomes and Contributors to Weight Loss in a Cancer Cachexia Clinic
Egidio Del Fabbro et al.
JOURNAL OF PALLIATIVE MEDICINE (2011)
Definition and classification of cancer cachexia: an international consensus
Kenneth Fearon et al.
LANCET ONCOLOGY (2011)
Oral Resveratrol Therapy Inhibits Cancer-Induced Skeletal Muscle and Cardiac Atrophy In Vivo
Scott Shadfar et al.
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL (2011)
STAT3 Activation in Skeletal Muscle Links Muscle Wasting and the Acute Phase Response in Cancer Cachexia
Andrea Bonetto et al.
PLOS ONE (2011)
Strength Training as a Countermeasure to Aging Muscle and Chronic Disease
Ben F. Hurley et al.
SPORTS MEDICINE (2011)
Cachexia, Malnutrition, the Refeeding Syndrome, and Lessons from Goldilocks
J. Alexander Palesty et al.
SURGICAL CLINICS OF NORTH AMERICA (2011)
Refeeding Syndrome: A Literature Review
L. U. R. Khan et al.
GASTROENTEROLOGY RESEARCH AND PRACTICE (2011)
Combined approach to counteract experimental cancer cachexia: eicosapentaenoic acid and training exercise
Fabio Penna et al.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE (2011)
Decreased NADPH oxidase expression and antioxidant activity in cachectic skeletal muscle
Melanie J. Sullivan-Gunn et al.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE (2011)
The role of zinc in the anti-tumour and anti-cachectic activity of D-myo-inositol 1,2,6-triphosphate
S. T. Russell et al.
BRITISH JOURNAL OF CANCER (2010)
Regulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticals
Subash C. Gupta et al.
CANCER AND METASTASIS REVIEWS (2010)
Reversal of Cancer Cachexia and Muscle Wasting by ActRIIB Antagonism Leads to Prolonged Survival
Xiaolan Zhou et al.
CELL (2010)
GPR120 Is an Omega-3 Fatty Acid Receptor Mediating Potent Anti-inflammatory and Insulin-Sensitizing Effects
Da Young Oh et al.
CELL (2010)
Peroxisome Proliferator-activated Receptor γ Coactivator 1α or 1β Overexpression Inhibits Muscle Protein Degradation, Induction of Ubiquitin Ligases, and Disuse Atrophy
Jeffrey J. Brault et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
JunB transcription factor maintains skeletal muscle mass and promotes hypertrophy
Anna Raffaello et al.
JOURNAL OF CELL BIOLOGY (2010)
Targeted ablation of TRAF6 inhibits skeletal muscle wasting in mice
Pradyut K. Paul et al.
JOURNAL OF CELL BIOLOGY (2010)
Myostatin Decreases with Aerobic Exercise and Associates with Insulin Resistance
Dustin S. Hittel et al.
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE (2010)
Skeletal muscle wasting in cachexia and sarcopenia: molecular pathophysiology and impact of exercise training
Karsten Lenk et al.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE (2010)
Protein synthesis and the expression of growth-related genes are altered by running in human vastus lateralis and soleus muscles
Matthew P. Harber et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2009)
Localized accumulation of oxidative stress causes muscle atrophy through activation of an autophagic pathway
Michela Aucello et al.
AUTOPHAGY (2009)
Dietary supplementation with a specific combination of high protein, leucine, and fish oil improves muscle function and daily activity in tumour-bearing cachectic mice
K. van Norren et al.
BRITISH JOURNAL OF CANCER (2009)
Attenuation of proteolysis and muscle wasting by curcumin c3 complex in MAC16 colon tumour-bearing mice
Rafat A. Siddiqui et al.
BRITISH JOURNAL OF NUTRITION (2009)
Effects of matrine against the growth of human lung cancer and hepatoma cells as well as lung cancer cell migration
Ying Zhang et al.
CYTOTECHNOLOGY (2009)
Valosin-containing protein (VCP) is required for autophagy and is disrupted in VCP disease
Jeong-Sun Ju et al.
JOURNAL OF CELL BIOLOGY (2009)
During muscle atrophy, thick, but not thin, filament components are degraded by MuRF1-dependent ubiquitylation
Shenhav Cohen et al.
JOURNAL OF CELL BIOLOGY (2009)
Randomized Controlled Trial of Resistance or Aerobic Exercise in Men Receiving Radiation Therapy for Prostate Cancer
Roanne J. Segal et al.
JOURNAL OF CLINICAL ONCOLOGY (2009)
Anorexia-Cachexia Syndrome: A Systematic Review of the Role of Dietary Polyunsaturated Fatty Acids in the Management of Symptoms, Survival, and Quality of Life
Paolo Mazzotta et al.
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT (2009)
IL-6 and Serum Amyloid A Synergy Mediates Angiotensin II-Induced Muscle Wasting
Liping Zhang et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2009)
Inhibition of Atrogin-1/MAFbx Mediated MyoD Proteolysis Prevents Skeletal Muscle Atrophy In Vivo
Julie Lagirand-Cantaloube et al.
PLOS ONE (2009)
The role of cytokines in cancer cachexia
Josep M Argilés et al.
Current Opinion in Supportive and Palliative Care (2009)
Neuroinflammation facilitates LIF entry into brain: role of TNF
Weihong Pan et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2008)
Beneficial immune modulatory effects of a specific nutritional combination in a murine model for cancer cachexia
J. Faber et al.
BRITISH JOURNAL OF CANCER (2008)
Anticancer properties of oxidation products of docosahexaenoic acid
Rafat A. Siddiqui et al.
CHEMISTRY AND PHYSICS OF LIPIDS (2008)
Cachexia: A new definition
William J. Evans et al.
CLINICAL NUTRITION (2008)
The initiation factor eIF3-f is a major target for Atrogin1/MAFbx function in skeletal muscle atrophy
Julie Lagirand-Cantaloube et al.
EMBO JOURNAL (2008)
Moderate exercise is an antioxidant:: Upregulation of antioxidant genes by training
Mari-Carmen Gomez-Cabrera et al.
FREE RADICAL BIOLOGY AND MEDICINE (2008)
Sophocarpine and matrine inhibit the production of TNF-α and IL-6 in murine macrophages and prevent cachexia-related symptoms induced by colon26 adenocarcinoma in mice
Yuefan Zhang et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2008)
Muscle as an endocrine organ: Focus on muscle-derived interleukin-6
Bente K. Pedersen et al.
PHYSIOLOGICAL REVIEWS (2008)
FoxO3 controls autophagy in skeletal muscle in vivo
Cristina Mammucari et al.
CELL METABOLISM (2007)
FoxO3 coordinately activates protein degradation by the Autophagic/Lysosomal and proteasomal pathways in atrophying muscle cells
Jinghui Zhao et al.
CELL METABOLISM (2007)
The E3 ligase MuRF1 degrades myosin heavy chain protein in dexamethasone-treated skeletal muscle
Brian A. Clarke et al.
CELL METABOLISM (2007)
Effects of aerobic and resistance exercise in breast cancer patients receiving adjuvant chemotherapy: A multicenter randomized controlled trial
Kerry S. Courneya et al.
JOURNAL OF CLINICAL ONCOLOGY (2007)
Oxidative stress and wasting in cancer
Alessandro Laviano et al.
CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE (2007)
n-3 Fatty acids, cancer and cachexia:: a systematic review of the literature
Ramon Colomer et al.
BRITISH JOURNAL OF NUTRITION (2007)
Resveratrol does not ameliorate muscle wasting in different types of cancer cachexia models
Silvia Busquets et al.
CLINICAL NUTRITION (2007)
The influence of frequency, intensity, volume and mode of strength training on whole muscle cross-sectional area in humans
Mathias Wernbom et al.
SPORTS MEDICINE (2007)
Proteolytic mRNA expression in response to acute resistance exercise in human single skeletal muscle fibers
Yifan Yang et al.
JOURNAL OF APPLIED PHYSIOLOGY (2006)
PGC-1α a protects skeletal muscle from atrophy by suppressing Fox03 action and atrophy-specific gene transcription
Marco Sandri et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Redefining oxidative stress
Dean P. Jones
ANTIOXIDANTS & REDOX SIGNALING (2006)
Angiotensin II directly induces muscle protein catabolism through the ubiquitin-proteasome proteolytic pathway and may play a role in cancer cachexia
PM Sanders et al.
BRITISH JOURNAL OF CANCER (2005)
Physiological functions of the mitochondrial uncoupling proteins UCP2 and UCP3
MD Brand et al.
CELL METABOLISM (2005)
The modulation of prostate cancer risk with α-tocopherol:: A pilot randomized, controlled clinical trial
J Hernández et al.
JOURNAL OF UROLOGY (2005)
Metabolic control through the PGC-1 family of transcription coactivators
JD Lin et al.
CELL METABOLISM (2005)
The anti-inflammatory effect of exercise
AMW Petersen et al.
JOURNAL OF APPLIED PHYSIOLOGY (2005)
Both oxidative and nitrosative stress are associated with muscle wasting in tumour-bearing rats
E Barreiro et al.
FEBS LETTERS (2005)
Activation of UCPs gene expression in skeletal muscle can be independent on both circulating fatty acids and food intake involvement of ROS in a model of mouse cancer cachexia
S Busquets et al.
FEBS LETTERS (2005)
Measuring reactive species and oxidative damage in vivo and in cell culture:: how should you do it and what do the results mean?
B Halliwell et al.
BRITISH JOURNAL OF PHARMACOLOGY (2004)
Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy
M Sandri et al.
CELL (2004)
Regulation of protein catabolism by muscle-specific and cytokine-inducible ubiquitin ligase E3α-II during cancer cachexia
KS Kwak et al.
CANCER RESEARCH (2004)
Induction of proteasome expression in skeletal muscle is attenuated by inhibitors of NF-κB activation
SM Wyke et al.
BRITISH JOURNAL OF CANCER (2004)
Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression
SH Lecker et al.
FASEB JOURNAL (2004)
IKKβ/NF-κB activation causes severe muscle wasting in mice
DS Cai et al.
CELL (2004)
Naproxen, clenbuterol and insulin administration ameliorates cancer cachexia and reduce tumor growth in Walker 256 tumor-bearing rats
PM Piffar et al.
CANCER LETTERS (2003)
Antioxidant agents are effective in inducing lymphocyte progression through cell cycle in advanced cancer patients:: assessment of the most important laboratory indexes of cachexia and oxidative stress
G Mantovani et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2003)
Differential modulation of Toll-like receptors by fatty acids: preferential inhibition by n-3 polyunsaturated fatty acids
JY Lee et al.
JOURNAL OF LIPID RESEARCH (2003)
An integrated stress response regulates amino acid metabolism and resistance to oxidative stress
HP Harding et al.
MOLECULAR CELL (2003)
Functional foods: Benefits, concerns and challenges-a position paper from the American Council on Science and Health
CM Hasler
JOURNAL OF NUTRITION (2002)
Anticachectic effects of the natural herb Coptidis rhizoma and berberine on mice bearing colon 26/clone 20 adenocarcinoma
N Iizuka et al.
INTERNATIONAL JOURNAL OF CANCER (2002)
Muscle UCP-3 mRNA levels are elevated in weight loss associated with gastrointestinal adenocarcinoma in humans
P Collins et al.
BRITISH JOURNAL OF CANCER (2002)
Tumor necrosis factor-α exerts interleukin-6-dependent and -independent effects on cultured skeletal muscle cells
B Alvarez et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2002)
Role of cytokines in cancer cachexia in a murine model of intracerebral injection of human tumours
DRM Negri et al.
CYTOKINE (2001)
Curcumin, a natural product present in turmeric, decreases tumor growth but does not behave as an anticachectic compound in a rat model
S Busquets et al.
CANCER LETTERS (2001)
An important function of Nrf2 in combating oxidative stress: Detoxification of acetaminophen
KM Chan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Licorice and cancer
ZY Wang et al.
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL (2001)
Anticachectic effects of Coptidis rhizoma, an anti-inflammatory herb, on esophageal cancer cells that produce interleukin 6
N Iizuka et al.
CANCER LETTERS (2000)
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