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FEBS JOURNAL (2020)
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JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION (2020)
In vitro studies revealed a downregulation of Wnt/β-catenin cascade by active vitamin D and TX 527 analog in a Kaposi's sarcoma cellular model
Cinthya Tapia et al.
TOXICOLOGY IN VITRO (2020)
Aberrant WNT/CTNNB1 Signaling as a Therapeutic Target in Human Breast Cancer: Weighing the Evidence
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FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2020)
Noncalcemic Vitamin D Hydroxyderivatives Inhibit Human Oral Squamous Cell Carcinoma and Down-regulate Hedgehog and WNT/β-Catenin Pathways
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ANTICANCER RESEARCH (2020)
Vitamin D Suppresses Ovarian Cancer Growth and Invasion by Targeting Long Non-Coding RNA CCAT2
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INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Vitamin D deficiency as a potential risk factor for accelerated aging, impaired hippocampal neurogenesis and cognitive decline: a role for Wnt/β-catenin signaling
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AGING-US (2020)
Association between variation of circulating 25-OH vitamin D and methylation of secreted frizzled-related protein 2 in colorectal cancer
Hatim Boughanem et al.
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Vitamin D Signaling in Inflammation and Cancer: Molecular Mechanisms and Therapeutic Implications
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Vitamin D-Induced Molecular Mechanisms to Potentiate Cancer Therapy and to Reverse Drug-Resistance in Cancer Cells
Mariarosaria Negri et al.
NUTRIENTS (2020)
Vitamin D Effects on Cell Differentiation and Stemness in Cancer
Asuncion Fernandez-Barral et al.
CANCERS (2020)
No Evidence for Posttreatment Effects of Vitamin D and Calcium Supplementation on Risk of Colorectal Adenomas in a Randomized Trial
Audrey H. Calderwood et al.
CANCER PREVENTION RESEARCH (2019)
Effect of High-Dose vs Standard-Dose Vitamin D3 Supplementation on Progression-Free Survival Among Patients With Advanced or Metastatic Colorectal Cancer The SUNSHINE Randomized Clinical Trial
Kimmie Ng et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2019)
Higher Post-Operative Serum Vitamin D Level is Associated with Better Survival Outcome in Colorectal Cancer Patients
Antonio Markotic et al.
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL (2019)
Vitamin D and Wnt3A have additive and partially overlapping modulatory effects on gene expression and phenotype in human colon fibroblasts
Gemma Ferrer-Mayorga et al.
SCIENTIFIC REPORTS (2019)
Vitamin D-VDR Signaling Inhibits Wnt/β-Catenin-Mediated Melanoma Progression and Promotes Antitumor Immunity
Sathya Muralidhar et al.
CANCER RESEARCH (2019)
Inhibition of tumor cell proliferation in human uterine leiomyomas by vitamin D via Wnt/β-catenin pathway
Ana Corachan et al.
FERTILITY AND STERILITY (2019)
New insights into the mechanisms of epithelial-mesenchymal transition and implications for cancer
Anushka Dongre et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2019)
Depleting ovarian cancer stem cells with calcitriol
Amit Kumar Srivastava et al.
Oncotarget (2018)
Therapeutic efficacy of Vitamin D in experimental c-MET-beta-catenin-driven hepatocellular cancer
Akiko Matsuda et al.
GENE EXPRESSION (2018)
miR-372 and miR-373 enhance the stemness of colorectal cancer cells by repressing differentiation signaling pathways
Lu-Qin Wang et al.
MOLECULAR ONCOLOGY (2018)
Vitamin D-induced vitamin D receptor expression induces tamoxifen sensitivity in MCF-7 stem cells via suppression of Wnt/β-catenin signaling
Wei Zheng et al.
BIOSCIENCE REPORTS (2018)
Effects of supplemental calcium and vitamin D on the APC/-catenin pathway in the normal colorectal mucosa of colorectal adenoma patients
Siyu Liu et al.
MOLECULAR CARCINOGENESIS (2017)
Vitamin D receptor is a novel transcriptional regulator for Axin1
Dapeng Jin et al.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2017)
A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma
Tuomas Tammela et al.
NATURE (2017)
R-Spondin chromosome rearrangements drive Wnt-dependent tumour initiation and maintenance in the intestine
Teng Han et al.
NATURE COMMUNICATIONS (2017)
The regulation of β-catenin activity and function in cancer: therapeutic opportunities
Shuang Shang et al.
ONCOTARGET (2017)
Fine tuning of vitamin D receptor (VDR) activity by post-transcriptional and post-translational modifications
Ondrej Zenata et al.
ONCOTARGET (2017)
Loss of the vitamin D receptor in human breast and prostate cancers strongly induces cell apoptosis through downregulation of Wnt/β-catenin signaling
Yu Zheng et al.
BONE RESEARCH (2017)
Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities
Roel Nusse et al.
CELL (2017)
Effect of 1,25-dihydroxyvitamin D-3 on the Wnt pathway in non-malignant colonic cells
Charlotte Groeschel et al.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2016)
β-Catenin is required for T-cell leukemia initiation and MYC transcription downstream of Notch1
C. Gekas et al.
LEUKEMIA (2016)
VITAMIN D: METABOLISM, MOLECULAR MECHANISM OF ACTION, AND PLEIOTROPIC EFFECTS
Sylvia Christakos et al.
PHYSIOLOGICAL REVIEWS (2016)
The Non-Genomic Actions of Vitamin D
Charles S. Hii et al.
NUTRIENTS (2016)
MiR-205 and MiR-373 Are Associated with Aggressive Human Mucinous Colorectal Cancer
Annette Eyking et al.
PLOS ONE (2016)
Vitamin D Deficiency Promotes Liver Tumor Growth in Transforming Growth Factor-β/Smad3-Deficient Mice Through Wnt and Toll-like Receptor 7 Pathway Modulation
Jian Chen et al.
SCIENTIFIC REPORTS (2016)
Novel mechanisms for the vitamin D receptor (VDR) in the skin and in skin cancer
Daniel D. Bikle et al.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2015)
Effects of supplemental vitamin D and calcium on normal colon tissue and circulating biomarkers of risk for colorectal neoplasms
Roberd M. Bostick
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2015)
Calcipotriol Targets LRP6 to Inhibit Wnt Signaling in Pancreatic Cancer
Michael D. Arensman et al.
MOLECULAR CANCER RESEARCH (2015)
Inhibition of Mouse Breast Tumor-Initiating Cells by Calcitriol and Dietary Vitamin D
Youngtae Jeong et al.
MOLECULAR CANCER THERAPEUTICS (2015)
MYC and metabolism on the path to cancer
Annie L. Hsieh et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2015)
Vitamin D3 -dependent VDR signaling delays ron-mediated breast tumorigenesis through suppression of β-catenin activity
Abby L. Johnson et al.
ONCOTARGET (2015)
Activation of β-Catenin and Yap1 in Human Hepatoblastoma and Induction of Hepatocarcinogenesis in Mice
Junyan Tao et al.
GASTROENTEROLOGY (2014)
The role of vitamin D in reducing cancer risk and progression
David Feldman et al.
NATURE REVIEWS CANCER (2014)
Vitamin D Receptor and Retinoid X Receptor α Status and Vitamin D Insufficiency in Models of Murine Colitis
Rebecca W. Knackstedt et al.
CANCER PREVENTION RESEARCH (2013)
The structural basis of R-spondin recognition by LGR5 and RNF43
Po-Han Chen et al.
GENES & DEVELOPMENT (2013)
1α,25(OH)2-Dihydroxyvitamin D3/VDR protects the skin from UVB-induced tumor formation by interacting with the β-catenin pathway
Yan J. Jiang et al.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2013)
Vitamin D Is a Multilevel Repressor of Wnt/b-Catenin Signaling in Cancer Cells
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Cancers (2013)
WNT signalling pathways as therapeutic targets in cancer
Jamie N. Anastas et al.
NATURE REVIEWS CANCER (2013)
A Randomized Clinical Trial of the Effects of Supplemental Calcium and Vitamin D3 on the APC/β-Catenin Pathway in the Normal Mucosa of Colorectal Adenoma Patients
Thomas U. Ahearn et al.
CANCER PREVENTION RESEARCH (2012)
Wnt/β-Catenin Signaling and Disease
Hans Clevers et al.
CELL (2012)
The Nonskeletal Effects of Vitamin D: An Endocrine Society Scientific Statement
Clifford J. Rosen et al.
ENDOCRINE REVIEWS (2012)
Dysregulation of Wnt/β-Catenin Signaling in Gastrointestinal Cancers
Bryan D. White et al.
GASTROENTEROLOGY (2012)
Inactivation of the vitamin D receptor in APCmin/+ mice reveals a critical role for the vitamin D receptor in intestinal tumor growth
Wei Zheng et al.
INTERNATIONAL JOURNAL OF CANCER (2012)
Expression of Wnt3 Activates Wnt/β-Catenin Pathway and Promotes EMT-like Phenotype in Trastuzumab-Resistant HER2-Overexpressing Breast Cancer Cells
Yanyuan Wu et al.
MOLECULAR CANCER RESEARCH (2012)
VDR-RXR and TCF4/β-Catenin Cistromes in Colonic Cells of Colorectal Tumor Origin: Impact on c-FOS and c-MYC Gene Expression
Mark B. Meyer et al.
MOLECULAR ENDOCRINOLOGY (2012)
Recurrent R-spondin fusions in colon cancer
Somasekar Seshagiri et al.
NATURE (2012)
Comprehensive molecular characterization of human colon and rectal cancer
Donna M. Muzny et al.
NATURE (2012)
ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner
Huai-Xiang Hao et al.
NATURE (2012)
Vitamin D Intake Is Negatively Associated with Promoter Methylation of the Wnt Antagonist Gene DKK1 in a Large Group of Colorectal Cancer Patients
James B. Rawson et al.
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL (2012)
β-Catenin/LEF1 transactivates the microRNA-371-373 cluster that modulates the Wnt/β-catenin-signaling pathway
A-D Zhou et al.
ONCOGENE (2012)
MicroRNA-372 Is Associated with Poor Prognosis in Colorectal Cancer
Shinya Yamashita et al.
ONCOLOGY (2012)
LGR6 Is a High Affinity Receptor of R-Spondins and Potentially Functions as a Tumor Suppressor
Xing Gong et al.
PLOS ONE (2012)
Canonical Wnt signaling regulates Slug activity and links epithelial-mesenchymal transition with epigenetic Breast Cancer 1, Early Onset (BRCA1) repression
Zhao-Qiu Wu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Vitamin D receptor as a master regulator of the c-MYC/MXD1 network
Reyhaneh Salehi-Tabar et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Wnt Signaling in Cancer
Paul Polakis
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2012)
Vitamin D receptor (VDR)-mediated actions of 1α,25(OH)2vitarnin D3: Genomic and non-genomic mechanisms
Mark R. Haussler et al.
BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM (2011)
β-Catenin Signaling Controls Metastasis in Braf-Activated Pten-Deficient Melanomas
William E. Damsky et al.
CANCER CELL (2011)
Promoter methylation of Wnt antagonists DKK1 and SFRP1 is associated with opposing tumor subtypes in two large populations of colorectal cancer patients
James B. Rawson et al.
CARCINOGENESIS (2011)
Snail-1 regulates VDR signaling and inhibits 1,25(OH)-D3 action in osteosarcoma
Huiguang Yang et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2011)
KDM6B/JMJD3 histone demethylase is induced by vitamin D and modulates its effects in colon cancer cells
Fabio Pereira et al.
HUMAN MOLECULAR GENETICS (2011)
Overexpression of Hedgehog Signaling Is Associated with Epidermal Tumor Formation in Vitamin D Receptor-Null Mice
Arnaud E. Teichert et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2011)
β-Catenin pathway activation in breast cancer is associated with triple-negative phenotype but not with CTNNB1 mutation
Felipe C. Geyer et al.
MODERN PATHOLOGY (2011)
Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling
Wim de Lau et al.
NATURE (2011)
FZD7 has a critical role in cell proliferation in triple negative breast cancer
L. Yang et al.
ONCOGENE (2011)
Vitamin D Receptor Deficiency Enhances Wnt/β-Catenin Signaling and Tumor Burden in Colon Cancer
Maria Jesus Larriba et al.
PLOS ONE (2011)
Paneth cell marker expression in intestinal villi and colon crypts characterizes dietary induced risk for mouse sporadic intestinal cancer
Donghai Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/β-catenin signaling
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Wnt/β-Catenin Pathway Activation Is Enriched in Basal-Like Breast Cancers and Predicts Poor Outcome
Andrey I. Khramtsov et al.
AMERICAN JOURNAL OF PATHOLOGY (2010)
ApcMIN modulation of vitamin D secosteroid growth control
Haibo Xu et al.
CARCINOGENESIS (2010)
The Down-regulation of the Human MYC Gene by the Nuclear Hormone 1α,25-dihydroxyvitamin D3 is Associated with Cycling of Corepressors and Histone Deacetylases
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JOURNAL OF MOLECULAR BIOLOGY (2010)
Vitamin D Receptor Ligands, Adenomatous Polyposis Coli, and the Vitamin D Receptor FokI Polymorphism Collectively Modulate β-Catenin Activity in Colon Cancer Cells
Jan B. Egan et al.
MOLECULAR CARCINOGENESIS (2010)
Hypoxia and RAS-signaling pathways converge on, and cooperatively downregulate, the RECK tumor-suppressor protein through microRNAs
F. Loayza-Puch et al.
ONCOGENE (2010)
SPROUTY-2 and E-cadherin regulate reciprocally and dictate colon cancer cell tumourigenicity
A. Barbachano et al.
ONCOGENE (2010)
LRP6 overexpression defines a class of breast cancer subtype and is a target for therapy
Chia-Chen Liu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Effects of Vitamin D and Calcium on Proliferation and Differentiation In Normal Colon Mucosa: a Randomized Clinical Trial
Veronika Fedirko et al.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2009)
DICKKOPF-4 and -2 genes are upregulated in human colorectal cancer
Akira Matsui et al.
CANCER SCIENCE (2009)
Snail2 cooperates with Snail1 in the repression of vitamin D receptor in colon cancer
Maria Jesus Larriba et al.
CARCINOGENESIS (2009)
Cystatin D is a candidate tumor suppressor gene induced by vitamin D in human colon cancer cells
Silvia Alvarez-Diaz et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
Vitamin D Receptor Modulates the Neoplastic Phenotype Through Antagonistic Growth Regulatory Signals
Haibo Xu et al.
MOLECULAR CARCINOGENESIS (2009)
SNAI1 expression in colon cancer related with CDH1 and VDR downregulation in normal adjacent tissue
C. Pena et al.
ONCOGENE (2009)
Macrophage-derived IL-1β stimulates Wnt signaling and growth of colon cancer cells: a crosstalk interrupted by vitamin D3
P. Kaler et al.
ONCOGENE (2009)
Control of TCF-4 Expression by VDR and Vitamin D in the Mouse Mammary Gland and Colorectal Cancer Cell Lines
Marcy E. Beildeck et al.
PLOS ONE (2009)
Blood biomarkers of vitamin D status
Joseph E. Zerwekh
AMERICAN JOURNAL OF CLINICAL NUTRITION (2008)
In vivo binding to and functional repression of the VDR gene promoter by SLUG in human breast cells
Mukul K. Mittal et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Dietary induction of colonic tumors in a mouse model of sporadic colon cancer
Kan Yang et al.
CANCER RESEARCH (2008)
Epigenetic gene silencing in the Wnt pathway in breast cancer
George J. Klarmann et al.
EPIGENETICS (2008)
RhoA-ROCK and p38MAPK-MSK1 mediate vitamin D effects on gene expression, phenotype, and Wnt pathway in colon cancer cells
Paloma Ordonez-Moran et al.
JOURNAL OF CELL BIOLOGY (2008)
Inactivation of the vitamin D receptor enhances susceptibility of murine skin to UV-induced tumorigenesis
Tara I. Ellison et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2008)
Correlation between β-catenin mutations and expression of Wnt-signaling target genes in hepatocellular carcinoma
Madeleine Austinat et al.
MOLECULAR CANCER (2008)
DICKKOPF-4 is induced by TCF/β-catenin and upregulated in human colon cancer, promotes tumour cell invasion and angiogenesis and is repressed by 1α, 25-dihydroxyvitamin D3
N. Pendas-Franco et al.
ONCOGENE (2008)
The Vitamin D Receptor Is a Wnt Effector that Controls Hair Follicle Differentiation and Specifies Tumor Type in Adult Epidermis
Hector G. Palmer et al.
PLOS ONE (2008)
A genome-wide RNAi screen for Wnt/β-catenin pathway components identifies unexpected roles for TCF transcription factors in cancer
Wei Tang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Wnt pathway-related gene expression in inflammatory bowel disease
Joann You et al.
DIGESTIVE DISEASES AND SCIENCES (2008)
Frequent epigenetic inactivation of DICKKOPF family genes in human gastrointestinal tumors
Hironobu Sato et al.
CARCINOGENESIS (2007)
A vitamin D analogue inhibits colonic carcinogenesis in the AOM/DSS model
Alessandro Fichera et al.
JOURNAL OF SURGICAL RESEARCH (2007)
The Wnt antagonist DICKKOPF-1 gene is induced by 1α,25-dihydroxyvitamin D3 associated to the differentiation of human colon cancer cells
Oscar Aguilera et al.
CARCINOGENESIS (2007)
Vitamin D regulates the phenotype of human breast cancer cells
Natalia Pendas-Franco et al.
DIFFERENTIATION (2007)
The inhibition of Wnt/β-catenin signalling by 1α,25-dihydroxyvitamin D3 is abrogated by Snail1 in human colon cancer cells
Maria Jesus Larriba et al.
ENDOCRINE-RELATED CANCER (2007)
A Wnt-Axin2-GSK3β cascade regulates Snail1 activity in breast cancer cells
Jong In Yook et al.
NATURE CELL BIOLOGY (2006)
The expression levels of the transcriptional regulators p300 and CtBP modulate the correlations between SNAIL, ZEB1, E-cadherin and vitamin D receptor in human colon carcinomas
Cristina Pena et al.
INTERNATIONAL JOURNAL OF CANCER (2006)
Epigenetic inactivation of the Wnt antagonist DICKKOPF-1 (DKK-1) gene in human colorectal cancer
O. Aguilera et al.
ONCOGENE (2006)
Vitamin D receptor agonists specifically modulate the volume of the ligand-binding pocket
F Molnár et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
The molecular basis of vitamin D receptor and β-catenin crossregulation
S Shah et al.
MOLECULAR CELL (2006)
Genotype-phenotype correlation in hepatocellular adenoma: New classification and relationship with HCC
J Zucman-Rossi et al.
HEPATOLOGY (2006)
The role of vitamin D in cancer prevention
CF Garland et al.
AMERICAN JOURNAL OF PUBLIC HEALTH (2006)
E-cadherin and vitamin D receptor regulation by SNAIL and ZEB1 in colon cancer:: clinicopathological correlations
C Peña et al.
HUMAN MOLECULAR GENETICS (2005)
Dietary components modify gene expression: Implications for carcinogenesis
K Yang et al.
JOURNAL OF NUTRITION (2005)
Wnt-dependent regulation of the E-cadherin repressor snail
JI Yook et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
The Wnt antagonist DICKKOPF-1 gene is a downstream target of β-catenin/TCF and is downregulated in human colon cancer
JM Gonzálex-Sancho et al.
ONCOGENE (2005)
FGF-20 and DKK1 are transcriptional targets of β-catenin and FGF-20 is implicated in cancer and development
MN Chamorro et al.
EMBO JOURNAL (2005)
Glycogen synthase kinase-3 is an endogenous inhibitor of snail transcription: implications for the epithelial-mesenchymal transition
RE Bachelder et al.
JOURNAL OF CELL BIOLOGY (2005)
The transcription factor SNAIL represses vitamin D receptor expression and responsiveness in human colon cancer
HG Pálmer et al.
NATURE MEDICINE (2004)
A functional genomics approach for the identification of putative tumor suppressor genes: Dickkopf-1 as suppressor of HeLa cell transformation
AM Mikheev et al.
CARCINOGENESIS (2004)
DKK1, a negative regulator of Wnt signaling, is a target of the β-catenin/TCF pathway
A Niida et al.
ONCOGENE (2004)
Dickkopf-1 antagonizes Wnt signaling independent of β-catenin in human mesothelioma
AY Lee et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
Dual regulation of Snail by GSK-3β-mediated phosphorylation in control of epithelial-mesenchymal transition
BHP Zhou et al.
NATURE CELL BIOLOGY (2004)
Vitamin D3 receptor ablation sensitizes skin to chemically induced tumorigenesis
GM Zinser et al.
CARCINOGENESIS (2002)
Kremen proteins are Dickkopf receptors that regulate Wnt/β-catenin signalling
BY Mao et al.
NATURE (2002)
Vitamin D3 promotes the differentiation of colon carcinoma cells by the induction of E-cadherin and the inhibition of β-catenin signaling
HG Pálmer et al.
JOURNAL OF CELL BIOLOGY (2001)
Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6
MV Semënov et al.
CURRENT BIOLOGY (2001)
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