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CXCR7/CXCR4 Heterodimer Constitutively Recruits β-Arrestin to Enhance Cell Migration
Fabien M. Decaillot et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Leukemia Stem Cells and Microenvironment: Biology and Therapeutic Targeting
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JOURNAL OF CLINICAL ONCOLOGY (2011)
The chemokine CXCL12 and its receptor CXCR4 promote glioma stem cell-mediated VEGF production and tumour angiogenesis via PI3K/AKT signalling
Yi-fang Ping et al.
JOURNAL OF PATHOLOGY (2011)
Prognostic Impact of CXCR4 and CXCR7 Expression in Pancreatic Adenocarcinoma
Florian Gebauer et al.
JOURNAL OF SURGICAL ONCOLOGY (2011)
Identification and manipulation of tumor associated macrophages in human cancers
Moniek Heusinkveld et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2011)
CXCR4 positive cells from Lewis lung carcinoma cell line have cancer metastatic stem cell characteristics
Wei-Qi Nian et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2011)
A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable
Hua Tian et al.
NATURE (2011)
A vascular niche and a VEGF-Nrp1 loop regulate the initiation and stemness of skin tumours
Benjamin Beck et al.
NATURE (2011)
Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs
Thordur Oskarsson et al.
NATURE MEDICINE (2011)
The elusive nature and function of mesenchymal stem cells
Cesar Nombela-Arrieta et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2011)
Functional Heterogeneity of Breast Fibroblasts Is Defined by a Prostaglandin Secretory Phenotype that Promotes Expansion of Cancer-Stem Like Cells
Jenny A. Rudnick et al.
PLOS ONE (2011)
Epigenetic Changes of CXCR4 and Its Ligand CXCL12 as Prognostic Factors for Sporadic Breast Cancer
Edneia A. S. Ramos et al.
PLOS ONE (2011)
Contribution of cancer stem cells to tumor vasculogenic mimicry
Xiao-hong Yao et al.
PROTEIN & CELL (2011)
Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-κB-Dependent Manner
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CANCER CELL (2010)
CXCR4 Signaling Regulates Metastasis of Chemoresistant Melanoma Cells by a Lymphatic Metastatic Niche
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Macrophage Diversity Enhances Tumor Progression and Metastasis
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CELL (2010)
CD44, a therapeutic target for metastasising tumours
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EUROPEAN JOURNAL OF CANCER (2010)
Hypoxia-inducible factor-2 is a novel regulator of aberrant CXCL12 expression in multiple myeloma plasma cells
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HAEMATOLOGICA-THE HEMATOLOGY JOURNAL (2010)
The Essential Functions of Adipo-osteogenic Progenitors as the Hematopoietic Stem and Progenitor Cell Niche
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IMMUNITY (2010)
fCXCR4 and CXCR7 regulate angiogenesis and CT26.WT tumor growth independent from SDF-1
Otto Kollmar et al.
INTERNATIONAL JOURNAL OF CANCER (2010)
Effects of human mesenchymal stem cells on ER-positive human breast carcinoma cells mediated through ER-SDF-1/CXCR4 crosstalk
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Macrophages may promote cancer growth via a GM-CSF/HB-EGF paracrine loop that is enhanced by CXCL12
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MOLECULAR CANCER (2010)
Wnt activity defines colon cancer stem cells and is regulated by the microenvironment
Louis Vermeulen et al.
NATURE CELL BIOLOGY (2010)
A New Mesenchymal Stem Cell (MSC) Paradigm: Polarization into a Pro-Inflammatory MSC1 or an Immunosuppressive MSC2 Phenotype
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CXCL12, CXCR4 and CXCR7 Expression in brain metastases
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CANCER BIOLOGY & THERAPY (2009)
Glioma Tumor Stem-Like Cells Promote Tumor Angiogenesis and Vasculogenesis via Vascular Endothelial Growth Factor and Stromal-Derived Factor 1
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CANCER RESEARCH (2009)
Increased expression of SDF-1/CXCR4 is associated with lymph node metastasis of invasive micropapillary carcinoma of the breast
Fangfang Liu et al.
HISTOPATHOLOGY (2009)
Down-regulation of CXCL12 mRNA expression by promoter hypermethylation and its association with metastatic progression in human breast carcinomas
Wei Zhou et al.
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NK Cells Recognize and Kill Human Glioblastoma Cells with Stem Cell-Like Properties
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Highly tumorigenic lung cancer CD133+ cells display stem-like features and are spared by cisplatin treatment
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell-suppressive activity
Kiavash Movahedi et al.
BLOOD (2008)
Carcinoma-associated fibroblast-like differentiation of human mesenchymal stem cells
Pravin J. Mishra et al.
CANCER RESEARCH (2008)
The epithelial-mesenchymal transition generates cells with properties of stem cells
Sendurai A. Mani et al.
CELL (2008)
Cancer stem cells: implications for the progression and treatment of metastatic disease
A. K. Croker et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2008)
The critical role of SDF-1/CXCR4 axis in cancer and cancer stem cells metastasis
S. Gellmini et al.
JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION (2008)
被撤回的出版物: The role of CXCR7/RDC1 as a chemokine receptor for CXCL12/SDF-1 in prostate cancer (Retracted article. See vol. 298, 2022)
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JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Concise review: Mesenchymal stem cells: Their phenotype, differentiation capacity, immunological features, and potential for homing
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STEM CELLS (2007)
Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer
Patrick C. Hermann et al.
CELL STEM CELL (2007)
MIF is a noncognate ligand of CXC chemokine receptors in inflammatory and atherogenic cell recruitment
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NATURE MEDICINE (2007)
Niche-to-niche migration of bone-marrow-derived cells
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TRENDS IN MOLECULAR MEDICINE (2007)
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CANCER CELL (2007)
Maintenance of the hematopoietic stem cell pool by CXCL12-CXCR4 chemokine signaling in bone marrow stromal cell niches
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IMMUNITY (2006)
The pleiotropic effects of the SDF-1-CXCR4 axis in organogenesis, regeneration and tumorigenesis
M. Z. Ratajczak et al.
LEUKEMIA (2006)
A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development
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JOURNAL OF EXPERIMENTAL MEDICINE (2006)
Silencing of epithelial CXCL12 expression by DNA hypermethylation promotes colonic carcinoma metastasis
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ONCOGENE (2006)
Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement
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CYTOTHERAPY (2006)
CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells
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The stem-cell niche as an entity of action
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Gr-1+CD115+ immature myeloid suppressor cells mediate the development of tumor-induced T regulatory cells and T-cell anergy in tumor-bearing host
B Huang et al.
CANCER RESEARCH (2006)
CXCR4 regulates migration and development of human acute myelogenous leukemia stem cells in transplanted NOD/SCID mice
S Tavor et al.
CANCER RESEARCH (2004)
Inhibition of breast cancer metastasis by selective synthetic polypeptide against CXCR4
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CANCER RESEARCH (2004)
A small-molecule antagonist of CXCR4 inhibits intracranial growth of primary brain tumors
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Regulation of the chemokine receptor CXCR4 by hypoxia
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JOURNAL OF EXPERIMENTAL MEDICINE (2003)
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