相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。IL23 induces IL23R recycling and amplifies innate receptor-induced signalling and cytokines in human macrophages, and the IBD-protective IL23R R381Q variant modulates these outcomes
Rui Sun et al.
GUT (2020)
Dual-target IL-12-containing nanoparticles enhance T cell functions for cancer immunotherapy
Jieyu Li et al.
CELLULAR IMMUNOLOGY (2020)
IL-23 and PSMA-targeted duo-CAR T cells in Prostate Cancer Eradication in a preclinical model
Dawei Wang et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2020)
The significance of exosomes in the development and treatment of hepatocellular carcinoma
Xin Li et al.
MOLECULAR CANCER (2020)
P-MAPA and Interleukin-12 Reduce Cell Migration/Invasion and Attenuate the Toll-Like Receptor-Mediated Inflammatory Response in Ovarian Cancer SKOV-3 Cells: A Preliminary Study
Luiz Antonio Lupi et al.
MOLECULES (2020)
Interleukin-23 engineering improves CAR T cell function in solid tumors
Xingcong Ma et al.
NATURE BIOTECHNOLOGY (2020)
IL-12 regulates the expansion, phenotype, and function of murine NK cells activated by IL-15 and IL-18
Naoto Oka et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2020)
The Interleukin 22 Pathway Interacts with Mutant KRAS to Promote Poor Prognosis in Colon Cancer
Sarah McCuaig et al.
CLINICAL CANCER RESEARCH (2020)
B cell-Derived IL35 Drives STAT3-Dependent CD8+ T-cell Exclusion in Pancreatic Cancer
Bhalchandra Mirlekar et al.
CANCER IMMUNOLOGY RESEARCH (2020)
Intra-Tumoral Delivery of IL-27 Using Adeno-Associated Virus Stimulates Anti-tumor Immunity and Enhances the Efficacy of Immunotherapy
Aiyan Hu et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2020)
CXCL5 promotes gastric cancer metastasis by inducing epithelial-mesenchymal transition and activating neutrophils
Zheying Mao et al.
ONCOGENESIS (2020)
IL-27 Regulated CD4+IL-10+T Cells in Experimental Sjogren Syndrome
Jingjing Qi et al.
FRONTIERS IN IMMUNOLOGY (2020)
Tumor-Educated Neutrophils Activate Mesenchymal Stem Cells to Promote Gastric Cancer Growth and Metastasis
Jiahui Zhang et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2020)
Intratumoral IL12 mRNA Therapy Promotes TH1 Transformation of the Tumor Microenvironment
Susannah L. Hewitt et al.
CLINICAL CANCER RESEARCH (2020)
RORC overexpression as a sign of Th17 lymphocytes accumulation in multiple myeloma bone marrow
Ahlem Ben Hmid et al.
CYTOKINE (2020)
Localized Interleukin-12 for Cancer Immunotherapy
Khue G. Nguyen et al.
FRONTIERS IN IMMUNOLOGY (2020)
Decoding IL-23 Signaling Cascade for New Therapeutic Opportunities
Gloria Pastor-Fernandez et al.
CELLS (2020)
IL-27 along with IL-28B ameliorates the pulmonary redox impairment, inflammation and immunosuppression in benzo(a)pyrene induced lung cancer bearing mice
Debabrata Majumder et al.
LIFE SCIENCES (2020)
Serum concentration of interleukin-35 and its association with tumor stages and FOXP3 gene polymorphism in patients with prostate cancer
Nazanin Chatrabnous et al.
CYTOKINE (2019)
Commensal Microbiota Promote Lung Cancer Development via γδ T Cells
Chengcheng Jin et al.
CELL (2019)
Human neutrophils activated via TLR8 promote Th17 polarization through IL-23
Nicola Tamassia et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2019)
IL-39 acts as a friend to pancreatic cancer (vol 36, 12, 2019)
Alicia A. Manning et al.
MEDICAL ONCOLOGY (2019)
Umbilical cord blood-derived Helios-positive regulatory T cells promote angiogenesis in acute lymphoblastic leukemia in mice via CCL22 and the VEGFA-VEGFR2 pathway
Xue Li et al.
MOLECULAR MEDICINE REPORTS (2019)
IL-27 confers a protumorigenic activity of regulatory T cells via CD39
Young-Jun Park et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
NCR- group 3 innate lymphoid cells orchestrate IL-23/IL-17 axis to promote hepatocellular carcinoma development
Yonghao Liu et al.
EBIOMEDICINE (2019)
Increased expression of the immunosuppressive interleukin-35 in patients with non-small cell lung cancer
Lisanne Heim et al.
BRITISH JOURNAL OF CANCER (2019)
The Immunobiology of the Interleukin-12 Family: Room for Discovery
Elia D. Tait Wojno et al.
IMMUNITY (2019)
Armored Inducible Expression of IL-12 Enhances Antitumor Activity of Glypican-3-Targeted Chimeric Antigen Receptor-Engineered T Cells in Hepatocellular Carcinoma
Ying Liu et al.
JOURNAL OF IMMUNOLOGY (2019)
Poly(I:C)-Mediated Death of Human Prostate Cancer Cell Lines Is Induced by Interleukin-27 Treatment
Olena Kourko et al.
JOURNAL OF INTERFERON AND CYTOKINE RESEARCH (2019)
Interleukin-35 is associated with the tumorigenesis and progression of prostate cancer
Jialin Zhu et al.
ONCOLOGY LETTERS (2019)
Diagnostic and prognostic value of serum IL-23 in colorectal cancer
Dina F. Elessawi et al.
ARAB JOURNAL OF GASTROENTEROLOGY (2019)
Interleukin-35 Dampens CD8+ T Cells Activity in Patients With Non-viral Hepatitis-Related Hepatocellular Carcinoma
Lanlan Yang et al.
FRONTIERS IN IMMUNOLOGY (2019)
IL-27 enhances IL-15/IL-18-mediated activation of human natural killer cells
Yeon Ho Choi et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2019)
Evidence for IL-35 Expression in Diffuse Large B-Cell Lymphoma and Impact on the Patient's Prognosis
Frederique Larousserie et al.
FRONTIERS IN ONCOLOGY (2019)
Regulatable interleukin-12 gene therapy in patients with recurrent high-grade glioma: Results of a phase 1 trial
E. Antonio Chiocca et al.
SCIENCE TRANSLATIONAL MEDICINE (2019)
IL-35 inhibits CD8+ T cells activity by suppressing expression of costimulatory molecule CD28 and Th1 cytokine production
Hua Jiang et al.
TRANSLATIONAL CANCER RESEARCH (2019)
Peritumoural CCL1 and CCL22 expressing cells in hepatocellular carcinomas shape the tumour immune infiltrate
Gabriela M. Wiedemann et al.
PATHOLOGY (2019)
Stereotactic Body Radiation and Interleukin-12 Combination Therapy Eradicates Pancreatic Tumors by Repolarizing the Immune Microenvironment
Bradley N. Mills et al.
CELL REPORTS (2019)
JAK/STAT Cytokine Signaling at the Crossroad of NK Cell Development and Maturation
Dagmar Gotthardt et al.
FRONTIERS IN IMMUNOLOGY (2019)
Mechanisms regulating PD-L1 expression on tumor and immune cells
Shuming Chen et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2019)
Ex vivo conditioning with IL-12 protects tumor-infiltrating CD8+ T cells from negative regulation by local IFN-γ
Lin Lin et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2019)
IL-23 in inflammatory bowel diseases and colon cancer
Markus F. Neurath
CYTOKINE & GROWTH FACTOR REVIEWS (2019)
Tumor-associated Macrophage-derived Interleukin-23 Interlinks Kidney Cancer Glutamine Addiction with Immune Evasion
Qiang Fu et al.
EUROPEAN UROLOGY (2019)
Non-small Cell Lung Cancer Cells Modulate the Development of Human CD1c+ Conventional Dendritic Cell Subsets Mediated by CD103 and CD205
Yong Lu et al.
FRONTIERS IN IMMUNOLOGY (2019)
Chemokines Modulate Immune Surveillance in Tumorigenesis, Metastasis, and Response to Immunotherapy
Anna E. Vilgelm et al.
FRONTIERS IN IMMUNOLOGY (2019)
Interleukin-35 as an Emerging Player in Tumor Microenvironment
Wenhua Xue et al.
JOURNAL OF CANCER (2019)
Interleukin (IL)-12 and IL-23 and Their Conflicting Roles in Cancer
Juming Yan et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2018)
CCL3 augments tumor rejection and enhances CD8(+) T cell infiltration through NK and CD103(+) dendritic cell recruitment via IFN
Frederick Allen et al.
ONCOIMMUNOLOGY (2018)
Intra-tumoral production of IL18, but not IL12, by TCR-engineered T cells is non-toxic and counteracts immune evasion of solid tumors
A. Kunert et al.
ONCOIMMUNOLOGY (2018)
Interleukin-35 Suppresses the Antitumor Activity of T Cells in Patients with Non-Small Cell Lung Cancer
Hong-Min Wang et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2018)
T-cell Homing Therapy for Reducing Regulatory T Cells and Preserving Effector T-cell Function in Large Solid Tumors
Jiemiao Hu et al.
CLINICAL CANCER RESEARCH (2018)
Revisiting Interleukin-12 as a Cancer Immunotherapy Agent
Pedro Berraondo et al.
CLINICAL CANCER RESEARCH (2018)
IL-35-producing B cells in gastric cancer patients
Ke Wang et al.
MEDICINE (2018)
Role of IL-23 signaling in the progression of premalignant oral lesions to cancer
Blaine Caughron et al.
PLOS ONE (2018)
Expression of IL-23R and IL-17 and the pathology and prognosis of urinary bladder carcinoma
Jian Liu et al.
ONCOLOGY LETTERS (2018)
IL23 and TGF-β diminish macrophage associated metastasis in pancreatic carcinoma
S. Mazher Hussain et al.
SCIENTIFIC REPORTS (2018)
Targeting interleukin-22 for cancer therapy
Anamarija Markota et al.
HUMAN VACCINES & IMMUNOTHERAPEUTICS (2018)
IL35 Hinders Endogenous Antitumor T-cell Immunity and Responsiveness to Immunotherapy in Pancreatic Cancer
Bhalchandra Mirlekar et al.
CANCER IMMUNOLOGY RESEARCH (2018)
Rapamycin Synergizes with Cisplatin in Antiendometrial Cancer Activation by Improving IL-27-Stimulated Cytotoxicity of NK Cells
Wen-Jie Zhou et al.
NEOPLASIA (2018)
CD19 CAR T Cells Expressing IL-12 Eradicate Lymphoma in Fully Lymphoreplete Mice through Induction of Host Immunity
Gray Kueberuwa et al.
MOLECULAR THERAPY-ONCOLYTICS (2018)
Administration of Interleukin-35-Conditioned Autologous Tolerogenic Dendritic Cells Prolong Allograft Survival After Heart Transplantation
Xianglan Liu et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2018)
Discovery of the IL-23/IL-17 Signaling Pathway and the Treatment of Psoriasis
Jason E. Hawkes et al.
JOURNAL OF IMMUNOLOGY (2018)
The PD-L1-and IL6-mediated dampening of the IL27/STAT1 anticancer responses are prevented by α-PD-L1 or α-IL6 antibodies
Catherine Rolvering et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2018)
IL-23 secreted by myeloid cells drives castration-resistant prostate cancer
Arianna Calcinotto et al.
NATURE (2018)
Macrophage-secreted interleukin-35 regulates cancer cell plasticity to facilitate metastatic colonization
Chih-Chan Lee et al.
NATURE COMMUNICATIONS (2018)
Interleukin-12p35 Knock Out Aggravates Doxorubicin-Induced Cardiac Injury and Dysfunction by Aggravating the Inflammatory Response, Oxidative Stress, Apoptosis and Autophagy in Mice
Jing Ye et al.
EBIOMEDICINE (2018)
Breast cancer cell-derived IL-35 promotes tumor progression via induction of IL-35-producing induced regulatory T cells
Shengnan Hao et al.
CARCINOGENESIS (2018)
Successful Anti-PD-1 Cancer Immunotherapy Requires T Cell-Dendritic Cell Crosstalk Involving the Cytokines IFN-γ and IL-12
Christopher S. Garris et al.
IMMUNITY (2018)
Combined Effect of IL-12Rβ2 and IL-23R Expression on Prognosis of Patients with Laryngeal Cancer
Ye Tao et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2018)
Interleukin-35 Expression in Non-Small Cell Lung Cancer is Associated with Tumor Progression
Mingfei Sun et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2018)
IL-27 gene therapy induces depletion of Tregs and enhances the efficacy of cancer immunotherapy
Jianmin Zhu et al.
JCI INSIGHT (2018)
Interleukin-27 Exerts Its Antitumor Effects by Promoting Differentiation of Hematopoietic Stem Cells to M1 Macrophages
Yukino Chiba et al.
CANCER RESEARCH (2018)
IL-27 mediates HLA class I up-regulation, which can be inhibited by the IL-6 pathway, in HLA-deficient Small Cell Lung Cancer cells
Grazia Carbotti et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2017)
Dual Roles of IL-27 in Cancer Biology and Immunotherapy
Marina Fabbi et al.
MEDIATORS OF INFLAMMATION (2017)
IL-27 triggers IL-10 production in Th17 cells via a c-Maf/RORγt/Blimp-1 signal to promote the progression of endometriosis
Kai-Kai Chang et al.
CELL DEATH & DISEASE (2017)
IL-12p35 induces expansion of IL-10 and IL-35-expressing regulatory B cells and ameliorates autoimmune disease
Ivy M. Dambuza et al.
NATURE COMMUNICATIONS (2017)
Interleukin-35 expression is associated with colon cancer progression
Jian Zhang et al.
ONCOTARGET (2017)
Colon cancer-induced interleukin-35 inhibits beta-catenin-mediated pro-oncogenic activity
QiangYue Jiang et al.
Oncotarget (2017)
IL-35 induces N2 phenotype of neutrophils to promote tumor growth
Jiu-Ming Zou et al.
ONCOTARGET (2017)
Enhanced antitumor effects by combining an IL-12/anti-DNA fusion protein with avelumab, an anti-PD-L1 antibody
Jonathan K. Fallon et al.
ONCOTARGET (2017)
CCL3 Enhances Antitumor Immune Priming in the Lymph Node via IFNγ with Dependency on Natural Killer Cells
Frederick Allen et al.
FRONTIERS IN IMMUNOLOGY (2017)
Regulation of NK Cell Activation and Effector Functions by the IL-12 Family of Cytokines: The Case of IL-27
Norberto Walter Zwirner et al.
FRONTIERS IN IMMUNOLOGY (2017)
Interleukin-35-Producing CD8α+ Dendritic Cells Acquire a Tolerogenic State and Regulate T Cell Function
Sergio Haller et al.
FRONTIERS IN IMMUNOLOGY (2017)
Tumor-targeted IL-12 combined with local irradiation leads to systemic tumor control via abscopal effects in vivo
Franziska Eckert et al.
ONCOIMMUNOLOGY (2017)
IL-6/IL-12 Cytokine Receptor Shuffling of Extra-and Intracellular Domains Reveals Canonical STAT Activation via Synthetic IL-35 and IL-39 Signaling
D. M. Floss et al.
SCIENTIFIC REPORTS (2017)
The good and the bad faces of STAT1 in solid tumours
Katrin Meissl et al.
CYTOKINE (2017)
Study of recombinant human interleukin-12 for treatment of complications after radiotherapy for tumor patients
Na Guo et al.
WORLD JOURNAL OF CLINICAL ONCOLOGY (2017)
Myc Cooperates with Ras by Programming Inflammation and Immune Suppression
Roderik M. Kortlever et al.
CELL (2017)
IL-23R-activated STAT3/STAT4 is essential for Th1/Th17-mediated CNS autoimmunity
Priscilla W. Lee et al.
JCI INSIGHT (2017)
Innate lymphoid cells in tissue homeostasis and diseases
Aline Ignacio et al.
WORLD JOURNAL OF HEPATOLOGY (2017)
Can local radiotherapy and IL-12 synergise to overcome the immunosuppressive tumor microenvironment and allow in situ tumor vaccination?
Gael Deplanque et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2017)
Interleukin-27 inhibits malignant behaviors of pancreatic cancer cells by targeting M2 polarized tumor associated macrophages
Lutian Yao et al.
CYTOKINE (2017)
Tumor-promoting effect of IL-23 in mammary cancer mediated by infiltration of M2 macrophages and neutrophils in tumor microenvironment
Wen Nie et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2017)
Innate lymphoid cells involve in tumorigenesis
Zhiqiang Tian et al.
INTERNATIONAL JOURNAL OF CANCER (2016)
IL-17 promotes tumor angiogenesis through Stat3 pathway mediated upregulation of VEGF in gastric cancer
Xiaoqin Wu et al.
TUMOR BIOLOGY (2016)
Association between IL-27 2905T/G genotypes and the risk and survival of cervical cancer: a case-control study
Guo-Qing Wang et al.
BIOMARKERS (2016)
Toxicities of chimeric antigen receptor T cells: recognition and management
Jennifer N. Brudno et al.
BLOOD (2016)
IL-17A-producing CD30+ Vδ1 T cells drive inflammation-induced cancer progression
Yoshitaka Kimura et al.
CANCER SCIENCE (2016)
An IL-27/Stat3 axis induces expression of programmed cell death 1 ligands (PD-L1/2) on infiltrating macrophages in lymphoma
Hasita Horlad et al.
CANCER SCIENCE (2016)
Interleukin (IL)-39 [IL-23p19/Epstein-Barr virus-induced 3 (Ebi3)] induces differentiation/expansion of neutrophils in lupus-prone mice
X. Wang et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2016)
Molecular Pathways: Interleukin-35 in Autoimmunity and Cancer
Yuliya Pylayeva-Gupta
CLINICAL CANCER RESEARCH (2016)
A novel IL-23p19/Ebi3 (IL-39) cytokine mediates inflammation in Lupus-like mice
Xiaoqian Wang et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2016)
Lag-3, Tim-3, and TIGIT: Co-inhibitory Receptors with Specialized Functions in Immune Regulation
Ana C. Anderson et al.
IMMUNITY (2016)
Combined therapy with oncolytic adenoviruses encoding TRAIL and IL-12 genes markedly suppressed human hepatocellular carcinoma both in vitro and in an orthotopic transplanted mouse model
Adel Galal El-Shemi et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2016)
mTOR Mediates IL-23 Induction of Neutrophil IL-17 and IL-22 Production
Feidi Chen et al.
JOURNAL OF IMMUNOLOGY (2016)
IL-35 Decelerates the Inflammatory Process by Regulating Inflammatory Cytokine Secretion and M1/M2 Macrophage Ratio in Psoriasis
Junfeng Zhang et al.
JOURNAL OF IMMUNOLOGY (2016)
IL-27 suppresses SKOV3 cells proliferation by enhancing STAT3 and inhibiting the Akt signal pathway
Zhu Zhang et al.
MOLECULAR IMMUNOLOGY (2016)
IL-35 expression in hepatocellular carcinoma cells is associated with tumor progression
Jun Long et al.
ONCOTARGET (2016)
Elevated level of Interleukin-35 in colorectal cancer induces conversion of T cells into iTr35 by activating STAT1/STAT3
Yanhui Ma et al.
ONCOTARGET (2016)
Epithelial IL-23R Signaling Licenses Protective IL-22 Responses in Intestinal Inflammation
Konrad Aden et al.
CELL REPORTS (2016)
Expanding Diversity in Molecular Structures and Functions of the IL-6/IL-12 Heterodimeric Cytokine Family
Hideaki Hasegawa et al.
FRONTIERS IN IMMUNOLOGY (2016)
CCL22-specific T Cells: Modulating the immunosuppressive tumor microenvironment
Evelina Martinenaite et al.
OncoImmunology (2016)
The ecto-ATPDase CD39 is involved in the acquisition of the immunoregulatory phenotype by M-CSF-macrophages and ovarian cancer tumor-associated macrophages: Regulatory role of IL-27
Senan M. d'Almeida et al.
ONCOIMMUNOLOGY (2016)
Toxicity and management in CAR T-cell therapy
Challice L. Bonifant et al.
MOLECULAR THERAPY-ONCOLYTICS (2016)
Prostaglandin E2 activates the mTORC1 pathway through an EP4/cAMP/PKA- and EP1/Ca2+-mediated mechanism in the human pancreatic carcinoma cell line PANC-1
Hui-Hua Chang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2015)
Interleukin-12: Functional activities and implications for disease
Sebastian Zundler et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2015)
Human tolerogenic dendritic cells produce IL-35 in the absence of other IL-12 family members
Karen O. Dixon et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2015)
Elevated IL-35 in bone marrow of the patients with acute myeloid leukemia
Jia Wang et al.
HUMAN IMMUNOLOGY (2015)
Interleukin-23-Independent IL-17 Production Regulates Intestinal Epithelial Permeability
Jacob S. Lee et al.
IMMUNITY (2015)
Asymmetric Action of STAT Transcription Factors Drives Transcriptional Outputs and Cytokine Specificity
Kiyoshi Hirahara et al.
IMMUNITY (2015)
Regulatory T cells-derived IL-35 promotes the growth of adult acute myeloid leukemia blasts
Qianshan Tao et al.
INTERNATIONAL JOURNAL OF CANCER (2015)
The Expression Levels of Transcription Factors T-bet, GATA-3, RORγt and FOXP3 in Peripheral Blood Lymphocyte (PBL) of Patients with Liver Cancer and their Significance
Ze-Wei Lin et al.
INTERNATIONAL JOURNAL OF MEDICAL SCIENCES (2015)
Interleukin-27 in T Cell Immunity
Yukiko Iwasaki et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2015)
Administration of DNA Encoding the Interleukin-27 Gene Augments Antitumour Responses through Non-adaptive Immunity
Q. Li et al.
SCANDINAVIAN JOURNAL OF IMMUNOLOGY (2015)
Interleukin-27 re-educates intratumoral myeloid cells and down-regulates stemness genes in non-small cell lung cancer
Irma Airoldi et al.
ONCOTARGET (2015)
IL-27 induces the expression of IDO and PD-L1 in human cancer cells
Grazia Carbotti et al.
ONCOTARGET (2015)
Th17 Cell Plasticity and Functions in Cancer Immunity
Leslie Guery et al.
BIOMED RESEARCH INTERNATIONAL (2015)
IL-12 secreting tumor-targeted chimeric antigen receptor T cells eradicate ovarian tumors in vivo
Mythili Koneru et al.
ONCOIMMUNOLOGY (2015)
New insights into IL-12-mediated tumor suppression
S. Tugues et al.
CELL DEATH AND DIFFERENTIATION (2015)
Interleukin-17 promotes angiogenesis by stimulating VEGF production of cancer cells via the STAT3/GIV signaling pathway in non-small-cell lung cancer
Bo Pan et al.
SCIENTIFIC REPORTS (2015)
Current perspective on the role of the interleukin-23/interleukin-17 axis in inflammation and disease (chronic arthritis and psoriasis)
Alberto Cauli et al.
IMMUNOTARGETS AND THERAPY (2015)
The prognostic value of preoperative serum levels of IL-12p40 and IL-23 for survival of patients with colorectal cancer
Noyko Stanilov et al.
APMIS (2014)
IL-17A Produced by γδ T Cells Promotes Tumor Growth in Hepatocellular Carcinoma
Shoubao Ma et al.
CANCER RESEARCH (2014)
IL-35 promotes pancreas cancer growth through enhancement of proliferation and inhibition of apoptosis: Evidence for a role as an autocrine growth factor
Michael B. Nicholl et al.
CYTOKINE (2014)
Circulating IL-35 in pancreatic ductal adenocarcinoma patients
Peng Jin et al.
HUMAN IMMUNOLOGY (2014)
Interleukin-17 Receptor A Signaling in Transformed Enterocytes Promotes Early Colorectal Tumorigenesis
Kepeng Wang et al.
IMMUNITY (2014)
Interleukin-35 induces regulatory B cells that suppress autoimmune disease
Ren-Xi Wang et al.
NATURE MEDICINE (2014)
Selected Cytokines in Patients with Pancreatic Cancer: A Preliminary Report
Wojciech Blogowski et al.
PLOS ONE (2014)
Interleukin-17 promotes development of castration-resistant prostate cancer potentially through creating an immunotolerant and pro-angiogenic tumor microenvironment
Qiuyang Zhang et al.
PROSTATE (2014)
Molecular mechanisms that influence the macrophage M1-M2 polarization balance
Nan Wang et al.
FRONTIERS IN IMMUNOLOGY (2014)
Th17 cellsin cancer: the ultimate identity crisis
Stefanie R. Bailey et al.
FRONTIERS IN IMMUNOLOGY (2014)
The IL-23-IL-17 immune axis: from mechanisms to therapeutic testing
Sarah L. Gaffen et al.
NATURE REVIEWS IMMUNOLOGY (2014)
STAT4 and T-bet Are Required for the Plasticity of IFN-γ Expression across Th2 Ontogeny and Influence Changes in Ifng Promoter DNA Methylation
Christopher L. Williams et al.
JOURNAL OF IMMUNOLOGY (2013)
Tumor-Derived IL-35 Promotes Tumor Growth by Enhancing Myeloid Cell Accumulation and Angiogenesis
Zhihui Wang et al.
JOURNAL OF IMMUNOLOGY (2013)
Increased Th17 Cells in the Tumor Microenvironment Is Mediated by IL-23 via Tumor-Secreted Prostaglandin E2
Xuesong Qian et al.
JOURNAL OF IMMUNOLOGY (2013)
IL-23 is pro-proliferative, epigenetically regulated and modulated by chemotherapy in non-small cell lung cancer
Anne-Marie Baird et al.
LUNG CANCER (2013)
IL-27 in tumor immunity and immunotherapy
Gopal Murugaiyan et al.
TRENDS IN MOLECULAR MEDICINE (2013)
HDAC expression levels may play a role in cisplatin resistant MPM
A. M. Baird et al.
LUNG CANCER (2013)
Local Delivery of Interleukin-12 Using T Cells Targeting VEGF Receptor-2 Eradicates Multiple Vascularized Tumors in Mice
Dhanalakshmi Chinnasamy et al.
CLINICAL CANCER RESEARCH (2012)
Increased Th17 and Regulatory T Cell Responses in EBV-Induced Gene 3-Deficient Mice Lead to Marginally Enhanced Development of Autoimmune Encephalomyelitis
Jin-Qing Liu et al.
JOURNAL OF IMMUNOLOGY (2012)
Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth
Sergei I. Grivennikov et al.
NATURE (2012)
The composition and signaling of the IL-35 receptor are unconventional
Lauren W. Collison et al.
NATURE IMMUNOLOGY (2012)
IL-12 family cytokines: immunological playmakers
Dario A. A. Vignali et al.
NATURE IMMUNOLOGY (2012)
Differential Effects of IL-12 on Tregs and Non-Treg T Cells: Roles of IFN-γ, IL-2 and IL-2R
Jingxian Zhao et al.
PLOS ONE (2012)
Interleukin 23 Promotes Hepatocellular Carcinoma Metastasis via NF-Kappa B Induced Matrix Metalloproteinase 9 Expression
Jian Li et al.
PLOS ONE (2012)
IL-27 increases the proliferation and effector functions of human naive CD8(+) T lymphocytes and promotes their development into Tc1 cells
Raphael Schneider et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2011)
Interleukin-35 Mediates Mucosal Immune Responses That Protect Against T-Cell-Dependent Colitis
Stefan Wirtz et al.
GASTROENTEROLOGY (2011)
IL-12 triggers a programmatic change in dysfunctional myeloid-derived cells within mouse tumors
Sid P. Kerkar et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
T-bet represses T(H)17 differentiation by preventing Runx1-mediated activation of the gene encoding ROR gamma t
Vanja Lazarevic et al.
NATURE IMMUNOLOGY (2011)
Involvement of CCR6/CCL20/IL-17 Axis in NSCLC Disease Progression
Sophie Kirshberg et al.
PLOS ONE (2011)
Induction of regulatory Tr1 cells and inhibition of TH17 cells by IL-27
Caroline Pot et al.
SEMINARS IN IMMUNOLOGY (2011)
Interleukin-23 acts as antitumor agent on childhood B-acute lymphoblastic leukemia cells
Claudia Cocco et al.
BLOOD (2010)
Tumor-Specific CD8+ T Cells Expressing Interleukin-12 Eradicate Established Cancers in Lymphodepleted Hosts
Sid P. Kerkar et al.
CANCER RESEARCH (2010)
IL-23 promotes growth and proliferation in human squamous cell carcinoma of the oral cavity
Masakatsu Fukuda et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2010)
Interleukin-27 Induces a STAT1/3-and NF-κB-dependent Proinflammatory Cytokine Profile in Human Monocytes
Christina Guzzo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
A Pivotal Role for Interleukin-27 in CD8(+) T Cell Functions and Generation of Cytotoxic T Lymphocytes
Noriko Morishima et al.
JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY (2010)
Molecular Pathways in the Induction of Interleukin-27-Driven Regulatory Type 1 Cells
Caroline Pot et al.
JOURNAL OF INTERFERON AND CYTOKINE RESEARCH (2010)
IL-35-mediated induction of a potent regulatory T cell population
Lauren W. Collison et al.
NATURE IMMUNOLOGY (2010)
Signal transducer and activator of transcription 4 limits the development of adaptive regulatory T cells
John T. O'Malley et al.
IMMUNOLOGY (2009)
IL-17 can promote tumor growth through an IL-6-Stat3 signaling pathway
Lin Wang et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2009)
IL-27 Is a Key Regulator of IL-10 and IL-17 Production by Human CD4+ T Cells
Gopal Murugaiyan et al.
JOURNAL OF IMMUNOLOGY (2009)
Cutting Edge: IL-27 Induces the Transcription Factor c-Maf, Cytokine IL-21, and the Costimulatory Receptor ICOS that Coordinately Act Together to Promote Differentiation of IL-10-Producing Tr1 Cells
Caroline Pot et al.
JOURNAL OF IMMUNOLOGY (2009)
A phase I trial of paclitaxel and trastuzumab in combination with interleukin-12 in patients with HER2/neu-expressing malignancies
Tanios S. Bekaii-Saab et al.
MOLECULAR CANCER THERAPEUTICS (2009)
The transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes
Richard G. Jenner et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Regulation of the class II and class I MHC pathways in human THP-1 monocytic cells by interleukin-27
Xiao Ming Feng et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Signal Transducer and Activator of Transcription 4 Is Required for the Transcription Factor T-bet to Promote T Helper 1 Cell-Fate Determination
Vivian T. Thieu et al.
IMMUNITY (2008)
Priming of naive CD8+T cells in the presence of IL-12 selectively enhances the survival of CD8(+)CD62L(hi) cells and results in superior anti-tumor activity in a tolerogenic murine model
C. Marcela Diaz-Montero et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2008)
The inhibitory cytokine IL-35 contributes to regulatory T-cell function
Lauren W. Collison et al.
NATURE (2007)
IL-35 is a novel cytokine with therapeutic effects against collagen-induced arthritis through the expansion of regulatory T cells and suppression of Th17 cells
Wanda Niedbala et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2007)
IL-23 promotes tumour incidence and growth
John L. Langowski et al.
NATURE (2006)
IL-27 suppresses CD28-medicated IL-2 production through suppressor of cytokine signaling 3
Toshiyuki Owaki et al.
JOURNAL OF IMMUNOLOGY (2006)
IL-27 limits IL-2 production during Th1 differentiation
AV Villarino et al.
JOURNAL OF IMMUNOLOGY (2006)
A role for IL-27 in early regulation of Th1 differentiation
T Owaki et al.
JOURNAL OF IMMUNOLOGY (2005)
An indispensable role for STAT1 in IL-27-induced T-bet expression but not proliferation of naive CD4+ T cells
S Kamiya et al.
JOURNAL OF IMMUNOLOGY (2004)
分享论文
