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Controlled delivery of antisense oligonucleotides: a brief review of current strategies
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EXPERT OPINION ON DRUG DELIVERY (2009)
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EXPERT REVIEW OF MOLECULAR DIAGNOSTICS (2009)
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INTERNATIONAL JOURNAL OF CANCER (2009)
Regulation of Epidermal Growth Factor Receptor Signaling in Human Cancer Cells by MicroRNA-7
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JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
MicroRNA-206 Targets notch3, Activates Apoptosis, and Inhibits Tumor Cell Migration and Focus Formation
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JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
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Supervised Risk Predictor of Breast Cancer Based on Intrinsic Subtypes
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JOURNAL OF CLINICAL ONCOLOGY (2009)
Topoisomerase II Alpha and Responsiveness of Breast Cancer to Adjuvant Chemotherapy
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JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2009)
miR-22 Inhibits Estrogen Signaling by Directly Targeting the Estrogen Receptor α mRNA
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MOLECULAR AND CELLULAR BIOLOGY (2009)
Human DNA methylomes at base resolution show widespread epigenomic differences
Ryan Lister et al.
NATURE (2009)
Segmental copy number variation shapes tissue transcriptomes
Charlotte N. Henrichsen et al.
NATURE GENETICS (2009)
Computational methods for discovering structural variation with next-generation sequencing
Paul Medvedev et al.
NATURE METHODS (2009)
Northern blot analysis for detection and quantification of RNA in pancreatic cancer cells and tissues
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NATURE PROTOCOLS (2009)
RNA-Seq: a revolutionary tool for transcriptomics
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NATURE REVIEWS GENETICS (2009)
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NUCLEIC ACIDS RESEARCH (2009)
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NUCLEIC ACIDS RESEARCH (2009)
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NUCLEIC ACIDS RESEARCH (2009)
Downregulation of miR-193b contributes to enhance urokinase-type plasminogen activator (uPA) expression and tumor progression and invasion in human breast cancer
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ONCOGENE (2009)
Methylation profiles of 22 candidate genes in breast cancer using high-throughput MALDI-TOF mass array
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ONCOGENE (2009)
Detection of Cancer with Serum miRNAs on an Oligonucleotide Microarray
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PLOS ONE (2009)
p53 represses c-Myc through induction of the tumor suppressor miR-145
Mohit Sachdeva et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Conserved Expression Patterns Predict microRNA Targets
William Ritchie et al.
PLOS COMPUTATIONAL BIOLOGY (2009)
MicroRNA signatures predict oestrogen receptor, progesterone receptor and HER2/neu receptor status in breast cancer
Aoife J. Lowery et al.
BREAST CANCER RESEARCH (2009)
Learning from positive examples when the negative class is undetermined-microRNA gene identification
Malik Yousef et al.
ALGORITHMS FOR MOLECULAR BIOLOGY (2008)
Histone methylation marks play important roles in predicting the methylation status of CpG islands
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BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Integrative analysis reveals the direct and indirect interactions between DNA copy number aberrations and gene expression changes
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BIOINFORMATICS (2008)
Estimation and assessment of raw copy numbers at the single locus level
H. Bengtsson et al.
BIOINFORMATICS (2008)
MicroRNA-7, a Homeobox D10 Target, Inhibits p21-Activated Kinase 1 and Regulates Its Functions
Sirigiri Divijendra Natha Reddy et al.
CANCER RESEARCH (2008)
MicroRNAs as regulators of epithelial-mesenchymal transition
Philip. A. Gregory et al.
CELL CYCLE (2008)
Novel Jet-Injection Technology for Nonviral Intratumoral Gene Transfer in Patients with Melanoma and Breast Cancer
Wolfgang Walther et al.
CLINICAL CANCER RESEARCH (2008)
Analysis of the MammaPrint breast cancer assay in a predominantly postmenopausal cohort
Ben S. Witmer et al.
CLINICAL CANCER RESEARCH (2008)
Improved binary PSO for feature selection using gene expression data
Li-Yeh Chuang et al.
COMPUTATIONAL BIOLOGY AND CHEMISTRY (2008)
被撤回的出版物: MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer (Retracted article. See vol. 175, pg. 192, 2023)
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GYNECOLOGIC ONCOLOGY (2008)
A cyclin D1/microRNA 17/20 regulatory feedback loop in control of breast cancer cell proliferation
Zuoren Yu et al.
JOURNAL OF CELL BIOLOGY (2008)
Endogenous human microRNAs that suppress breast cancer metastasis
Sohail F. Tavazoie et al.
NATURE (2008)
MicroRNAs accurately identify cancer tissue origin
Nitzan Rosenfeld et al.
NATURE BIOTECHNOLOGY (2008)
The mir-200 family and mir-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
Philip A. Gregory et al.
NATURE CELL BIOLOGY (2008)
Integrated genotype calling and association analysis of SNPs, common copy number polymorphisms and rare CNVs
Joshua M. Korn et al.
NATURE GENETICS (2008)
MicroRNA-126 regulates endothelial expression of vascular cell adhesion molecule 1
Tamia A. Harris et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Circulating microRNAs as stable blood-based markers for cancer detection
Patrick S. Mitchell et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
MicroRNA miR-21 overexpression in human breast cancer is associated with advanced clinical stage, lymph node metastasis and patient poor prognosis
Li-Xu Yan et al.
RNA (2008)
Normalization of microRNA expression levels in quantitative RT-PCR assays: Identification of suitable reference RNA targets in normal and cancerous human solid tissues
Heidi J. Peltier et al.
RNA (2008)
Quantitative hypermethylation of a small panel of genes augments the diagnostic accuracy in fine-needle aspirate washings of breast lesions
Carmen Jeronimo et al.
BREAST CANCER RESEARCH AND TREATMENT (2008)
DNA hypermethylation of PITX2 is a marker of poor prognosis in untreated lymph node-negative hormone receptor-positive breast cancer patients
Inko Nimmrich et al.
BREAST CANCER RESEARCH AND TREATMENT (2008)
Estrogen receptor and HER2/neu status affect epigenetic differences of tumor-related genes in primary breast tumors
Eiji Sunami et al.
BREAST CANCER RESEARCH (2008)
Switching from repression to activation: MicroRNAs can up-regulate translation
Shobha Vasudevan et al.
SCIENCE (2007)
Altered microRNA expression confined to specific epithelial cell Subpopulations in breast cancer
Lorenzo F. Sempere et al.
CANCER RESEARCH (2007)
Iet-7 regulates self renewal and tumorigenicity of breast cancer cells
Fengyan Yu et al.
CELL (2007)
MicroRNAs as potential agents to alter resistance to cytotoxic anticancer therapy
Joanne B. Weidhaas et al.
CANCER RESEARCH (2007)
miRRim: A novel system to find conserved miRNAs with high sensitivity and specificity
Goro Terai et al.
RNA (2007)
Epigenetic regulation as a new target for breast cancer therapy
Vered Stearns et al.
CANCER INVESTIGATION (2007)
Using expression profiling data to identify human microRNA targets
Jim C. Huang et al.
NATURE METHODS (2007)
Tumour invasion and metastasis initiated by microRNA 10b in breast cancer
Li Ma et al.
NATURE (2007)
Phase I and pharmacodynamic trial of the DNA methyltransferase inhibitor decitabine and carboplatin in solid tumors
Kim Appleton et al.
JOURNAL OF CLINICAL ONCOLOGY (2007)
Assessment of algorithms for high throughput detection of genomic copy number variation in oligonucleotide microarray data
Agnes Baross et al.
BMC BIOINFORMATICS (2007)
Analysis of microRNA expression by in situ hybridization with RNA oligonucleotide probes
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METHODS (2007)
A review of feature selection techniques in bioinformatics
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BIOINFORMATICS (2007)
MiRFinder: an improved approach and software implementation for genome-wide fast microRNA precursor scans
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BMC BIOINFORMATICS (2007)
Delivery of 5-aza-2′-deoxycytidine to cells using oligodeoxynucleotides
Christine B. Yoo et al.
CANCER RESEARCH (2007)
Differential regulation of microRNAs by p53 revealed by massively parallel Sequencing -: miR-34a is a p53 target that induces apoptosis and G1-arrest
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CELL CYCLE (2007)
A microRNA component of the p53 tumour suppressor network
Lin He et al.
NATURE (2007)
De novo SVM classification of precursor microRNAs from genomic pseudo hairpins using global and intrinsic folding measures
Kwang Loong Stanley Ng et al.
BIOINFORMATICS (2007)
Genetic and epigenetic alterations as biomarkers for cancer detection, diagnosis and prognosis
Zdenko Herceg et al.
MOLECULAR ONCOLOGY (2007)
Principles and limitations of computational microRNA gene and target finding
Morten Lindow et al.
DNA AND CELL BIOLOGY (2007)
Estrogen receptor alpha (ESR1) gene amplification is frequent in breast cancer
Frederik Holst et al.
NATURE GENETICS (2007)
miR-21-mediated tumor growth
M.-L. Si et al.
ONCOGENE (2007)
Analyzing gene expression data in terms of gene sets:: methodological issues
Jelle J. Goeman et al.
BIOINFORMATICS (2007)
Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation
Christine Mayr et al.
SCIENCE (2007)
Targets of genome copy number reduction in primary breast cancers identified by integrative genomics
Wei Chen et al.
GENES CHROMOSOMES & CANCER (2007)
Relative impact of nucleotide and copy number variation on gene expression phenotypes
Barbara E. Stranger et al.
SCIENCE (2007)
Coordinate suppression of ERBB2 and ERBB3 by enforced expression of micro-RNA miR-125a or miR-125b
Gary K. Scott et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype
Cherie Blenkiron et al.
GENOME BIOLOGY (2007)
High-resolution aCGH and expression profiling identifies a novel genomic subtype of ER negative breast cancer
Suet F. Chin et al.
GENOME BIOLOGY (2007)
Use of 70-gene signature to predict prognosis of patients with node-negative breast cancer: a prospective community-based feasibility study (RASTER)
[Anonymous]
LANCET ONCOLOGY (2007)
Progesterone receptors upregulate Wnt-1 to induce epidermal growth factor receptor transactivation and c-Src-dependent sustained activation of Erk1/2 mitogen-activated protein kinase in breast cancer cells
Emily J. Faivre et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
DNA methylation profiling of human chromosomes 6, 20 and 22
Florian Eckhardt et al.
NATURE GENETICS (2006)
Genomic and transcriptional aberrations linked to breast cancer pathophysiologies
Koei Chin et al.
CANCER CELL (2006)
Genetic profiling of chromosome 1 in breast cancer: mapping of regions of gains and losses and identification of candidate genes on 1q
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BRITISH JOURNAL OF CANCER (2006)
PSoL: a positive sample only learning algorithm for finding non-coding RNA genes
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BIOINFORMATICS (2006)
Distinct patterns of DNA copy number alteration are associated with different clinicopathological features and gene-expression subtypes of breast cancer
Anna Bergamaschi et al.
GENES CHROMOSOMES & CANCER (2006)
Genetic reclassification of histologic grade delineates new clinical subtypes of breast cancer
Anna V. Ivshina et al.
CANCER RESEARCH (2006)
MicroRNAs and chromosomal abnormalities in cancer cells
G. A. Calin et al.
ONCOGENE (2006)
Validation and clinical utility of a 70-gene prognostic signature for women with node-negative breast cancer
Marc Buyse et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2006)
ACE-it: a tool for genome-wide integration of gene dosage and RNA expression data
Wessel N. van Wieringen et al.
BIOINFORMATICS (2006)
Novel prognostic immunohistochemical biomarker panel for estrogen receptor-positive breast cancer
Brian Z. Ring et al.
JOURNAL OF CLINICAL ONCOLOGY (2006)
Hairpins in a Haystack: recognizing microRNA precursors in comparative genomics data
Jana Hertel et al.
BIOINFORMATICS (2006)
Optimized high-throughput microRNA expression profiling provides novel biomarker assessment of clinical prostate and breast cancer biopsies
Michael D. Mattie et al.
MOLECULAR CANCER (2006)
microRNAs exhibit high frequency genomic alterations in human cancer
Lin Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Topoisomerase IIα gene amplification predicts favorable treatment response to tailored and dose-escalated anthracycline-based adjuvant chemotherapy in HER-2/neu-amplified breast cancer:: Scandinavian Breast Group Trial 9401
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JOURNAL OF CLINICAL ONCOLOGY (2006)
Combining multi-species genomic data for microRNA identification using a Naive Bayes classifier
Malik Yousef et al.
BIOINFORMATICS (2006)
C-myc amplifications in primary breast carcinomas and their local recurrences
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JOURNAL OF CLINICAL PATHOLOGY (2006)
CAGE: cap analysis of gene expression
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NATURE METHODS (2006)
The MYC oncogene in breast cancer progression:: from benign epithelium to invasive carcinoma
C Corzo et al.
CANCER GENETICS AND CYTOGENETICS (2006)
Gene expression profiling in breast cancer: Understanding the molecular basis of histologic grade to improve prognosis
C Sotiriou et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2006)
Relationship of gene expression and chromosomal abnormalities in colorectal cancer
D Tsafrir et al.
CANCER RESEARCH (2006)
A microRNA expression signature of human solid tumors defines cancer gene targets
S Volinia et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
MicroRNAs as oncogenes
SM Hammond
CURRENT OPINION IN GENETICS & DEVELOPMENT (2006)
Microarray-based DNA methylation profiling: technology and applications
A Schumacher et al.
NUCLEIC ACIDS RESEARCH (2006)
Involvement of human micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell lines
Fanyin Meng et al.
GASTROENTEROLOGY (2006)
Jointly analyzing gene expression and copy number data in breast cancer using data reduction models
JA Berger et al.
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS (2006)
The epigenetic progenitor origin of human cancer
AP Feinberg et al.
NATURE REVIEWS GENETICS (2006)
Epigenetic silencing and deletion of the BRCA1 gene in sporadic breast cancer
Valgerdur Birgisdottir et al.
BREAST CANCER RESEARCH (2006)
Classification of real and pseudo microRNA precursors using local structure-sequence features and support vector machine
CH Xue et al.
BMC BIOINFORMATICS (2005)
Identification of clustered microRNAs using an ab initio prediction method -: art. no. 267
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BMC BIOINFORMATICS (2005)
Prediction and validation of microRNAs and their targets
I Bentwich
FEBS LETTERS (2005)
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
A Subramanian et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Retrospective analysis of topoisomerase IIa amplifications and deletions as predictive markers in primary breast cancer patients randomly assigned to cyclophosphamide, methotrexate, and fluorouracil or cyclophosphamide, epirubicin, and fluorouracil:: Danish Breast Cancer Cooperative Group
AS Knoop et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
The power of real-time PCR
MA Valasek et al.
ADVANCES IN PHYSIOLOGY EDUCATION (2005)
MicroRNA gene expression deregulation in human breast cancer
MV Iorio et al.
CANCER RESEARCH (2005)
Prediction of methylated CpGs in DNA sequences using a support vector machine
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FEBS LETTERS (2005)
Regulatable gene expression systems for gene therapy applications: Progress and future challenges
S Goverdhana et al.
MOLECULAR THERAPY (2005)
A robust algorithm for copy number detection using high-density oligonucleotide single nucleotide polymorphism genotyping arrays
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CANCER RESEARCH (2005)
Identification of hundreds of conserved and nonconserved human microRNAs
I Bentwich et al.
NATURE GENETICS (2005)
MicroRNAs: a developing story
AE Pasquinelli et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2005)
An Entropy-based gene selection method for cancer classification using microarray data
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BMC BIOINFORMATICS (2005)
An Entropy-based gene selection method for cancer classification using microarray data
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BMC BIOINFORMATICS (2005)
Phylogenetic shadowing and computational identification of human microRNA genes
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CELL (2005)
Human microRNA prediction through a probabilistic co-learning model of sequence and structure
JW Nam et al.
NUCLEIC ACIDS RESEARCH (2005)
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
GA Calin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Complementary miRNA pairs suggest a regulatory role for miRNA:miRNA duplexes
EC Lai et al.
RNA (2004)
MicroRNAs: Genomics, biogenesis, mechanism, and function
DP Bartel
CELL (2004)
Amplification of the BRCA2 pathway gene EMSY in sporadic breast cancer is related to negative outcome
C Rodriguez et al.
CLINICAL CANCER RESEARCH (2004)
Cancer genes and the pathways they control
B Vogelstein et al.
NATURE MEDICINE (2004)
A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer
S Paik et al.
NEW ENGLAND JOURNAL OF MEDICINE (2004)
Quantitative multiplex methylation-specific PCR assay for the detection of promoter hypermethylation in multiple genes in breast cancer
MJ Fackler et al.
CANCER RESEARCH (2004)
A global test for groups of genes: testing association with a clinical outcome
JJ Goeman et al.
BIOINFORMATICS (2004)
Gene expression alterations over large chromosomal regions in cancers include multiple genes unrelated to malignant progression
BG Masayesva et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
EGFR mutations in lung cancer:: Correlation with clinical response to gefitinib therapy
JG Paez et al.
SCIENCE (2004)
Association of breast cancer DNA methylation profiles with hormone receptor status and response to tamoxifen
M Widschwendter et al.
CANCER RESEARCH (2004)
Hybrid genetic algorithms for feature selection
IS Oh et al.
IEEE TRANSACTIONS ON PATTERN ANALYSIS AND MACHINE INTELLIGENCE (2004)
Will the new cytogenetics replace the old cytogenetics?
M Salman et al.
CLINICAL GENETICS (2004)
An integrated view of copy number and allelic alterations in the cancer genome using single nucleotide polymorphism arrays
XJ Zhao et al.
CANCER RESEARCH (2004)
High-resolution analysis of gene copy number alterations in human prostate cancer using CGH on cDNA microarrays: Impact of copy number on gene expression
M Wolf et al.
NEOPLASIA (2004)
The AMP-activated protein kinase cascade - a unifying system for energy control
D Carling
TRENDS IN BIOCHEMICAL SCIENCES (2004)
MeCP2 and MBD2 expression in human neoplastic and non-neoplastic breast tissue and its association with oestrogen receptor status
HM Müller et al.
BRITISH JOURNAL OF CANCER (2003)
Association of C-MYC amplification with progression from the in situ to the invasive stage in C-MYC-amplified breast carcinomas
EC Robanus-Maandag et al.
JOURNAL OF PATHOLOGY (2003)
PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes
VK Mootha et al.
NATURE GENETICS (2003)
The microRNAs of Caenorhabditis elegans
LP Lim et al.
GENES & DEVELOPMENT (2003)
Computational identification of Drosophila microRNA genes
EC Lai et al.
GENOME BIOLOGY (2003)
Gene expression profiling: methodological challenges, results, and prospects for addiction research
JD Pollock
CHEMISTRY AND PHYSICS OF LIPIDS (2002)
A gene-expression signature as a predictor of survival in breast cancer.
MJ van de Vijver et al.
NEW ENGLAND JOURNAL OF MEDICINE (2002)
Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumors
JR Pollack et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
C-myc oncogene amplification in ductal carcinoma in situ of the breast
S Aulmann et al.
BREAST CANCER RESEARCH AND TREATMENT (2002)
Selection bias in gene extraction on the basis of microarray gene-expression data
C Ambroise et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Exploring the etiology of haploinsufficiency
RA Veitia
BIOESSAYS (2002)
Gene expression profiling predicts clinical outcome of breast cancer
LJ van't Veer et al.
NATURE (2002)
Methylation-specific oligonucleotide microarray: A new potential for high-throughput methylation analysis
RS Gitan et al.
GENOME RESEARCH (2002)
Prognostic value of epidermal growth factor receptor (EGFR) and its relationship to the estrogen receptor status in 1029 patients with breast cancer
S Tsutsui et al.
BREAST CANCER RESEARCH AND TREATMENT (2002)
DNA methylation patterns in hereditary human cancers mimic sporadic tumorigenesis
M Esteller et al.
HUMAN MOLECULAR GENETICS (2001)
An extensive class of small RNAs in Caenorhabditis elegans
RC Lee et al.
SCIENCE (2001)
Direct retroviral delivery of human cytochrome P4502B6 for gene-directed enzyme prodrug therapy of cancer
O Kan et al.
CANCER GENE THERAPY (2001)
Comprehensive copy number and gene expression profiling of the 17q23 amplicon in human breast cancer
O Monni et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Significance analysis of microarrays applied to the ionizing radiation response
VG Tusher et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Quantitative assessment of DNA microarrays - Comparison with Northern blot analyses
M Taniguchi et al.
GENOMICS (2001)
Absolute quantification of mRNA using real-time reverse transcription polymerase chain reaction assays
SA Bustin
JOURNAL OF MOLECULAR ENDOCRINOLOGY (2000)
Singular value decomposition for genome-wide expression data processing and modeling
O Alter et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Gene expression analysis by massively parallel signature sequencing (MPSS) on microbead arrays
S Brenner et al.
NATURE BIOTECHNOLOGY (2000)