4.6 Article

Involvement of DNA Repair Genes and System of Radiation-Induced Activation of Transposons in Formation of Transgenerational Effects

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Summary: Parental exposure to radiation not only leads to mutation induction in the germline of irradiated animals but also affects their non-exposed offspring. Laboratory studies have shown compromised viability, fertility, and genome stability among the non-exposed offspring of irradiated parents. The epigenetic phenomenon of radiation-induced transgenerational effects has been established, but further research is needed to understand its manifestation in populations inhabiting radioactive-contaminated areas and the underlying mechanisms.

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