期刊
CRYSTALS
卷 11, 期 1, 页码 -出版社
MDPI
DOI: 10.3390/cryst11010054
关键词
biocompatibility; biodegradation; Mg-0; 5Ca-xZr alloys
资金
- Romanian Ministry of Research and Innovation, CCCDI-UEFSCDI, within PNCDI III [PN-III-P1-1.2-PCCDI-207-0239/60PCCDI 2018]
The study confirms that Mg-0.5Ca-xZr alloys have good biocompatibility and biodegradability, making them suitable for use as materials for new orthopedic devices.
Biodegradable alloys in Mg have the advantages of traditional metallic materials and those of biodegradable polymers with superior strength, lower density and ideal rigidity for fixing bone fractures. The biocompatibility and biodegradability of the five concentrations of Mg-0.5Ca-xZr alloys used were assessed using clinical and laboratory examinations that followed over time: tissue reaction, histological and imaging (RX, CT and SEM) evolution at 1, 2, 4 and 8 weeks after implant. The main purpose of this study was to investigate in vivo the long-term effect of Mg-0.5Ca-xZr alloys in rats. The results confirmed that Mg-0.5Ca-xZr alloys are biocompatible and biodegradable and are recommended to be used as possible materials for new orthopedics devices.
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