期刊
GENES
卷 12, 期 1, 页码 -出版社
MDPI
DOI: 10.3390/genes12010049
关键词
Solea senegalensis; cytogenetic map; BAC-FISH; physical map; comparative genomics
资金
- Spanish Ministerio de Ciencia e Innovacion MICINNFEDER [AGL2014-51860-C2-1-P, RTI2018-096847-B-C21]
- Junta de Andalucia, (Spain)
- UCA
The high-density genome mapping of Solea senegalensis revealed important characteristics of its genome organization and evolution, such as a possible sex proto-chromosome pair and conserved chromosomes with linked genes in distant species. These findings provide valuable insights into the chromosome dynamics and evolution of this species.
Solea senegalensis aquaculture production has experienced a great increase in the last decade and, consequently, the genome knowledge of the species is gaining attention. In this sense, obtaining a high-density genome mapping of the species could offer clues to the aquaculture improvement in those aspects not resolved so far. In the present article, a review and new processed data have allowed to obtain a high-density BAC-based cytogenetic map of S. senegalensis beside the analysis of the sequences of such BAC clones to achieve integrative data. A total of 93 BAC clones were used to localize the chromosome complement of the species and 588 genes were annotated, thus almost reaching the 2.5% of the S. senegalensis genome sequences. As a result, important data about its genome organization and evolution were obtained, such as the lesser gene density of the large metacentric pair compared with the other metacentric chromosomes, which supports the theory of a sex proto-chromosome pair. In addition, chromosomes with a high number of linked genes that are conserved, even in distant species, were detected. This kind of result widens the knowledge of this species' chromosome dynamics and evolution.
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