相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Sunscreen protection factor enhancement through supplementation with Rambutan (Nephelium lappaceum L) ethanolic extract
Milleno Dantas Mota et al.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY (2020)
Of Drugs and Trypanosomatids: New Tools and Knowledge to Reduce Bottlenecks in Drug Discovery
Arijit Bhattacharya et al.
GENES (2020)
Current and emerging medications for the treatment of leishmaniasis
Jaya Chakravarty et al.
EXPERT OPINION ON PHARMACOTHERAPY (2019)
Cinnamomum cassia exhibits antileishmanial activity against Leishmania donovani infection in vitro and in vivo
Farhat Afrin et al.
PLOS NEGLECTED TROPICAL DISEASES (2019)
Increased ROS generation causes apoptosis-like death: Mechanistic insights into the anti-Leishmania activity of a potent ruthenium(II) complex
Monica Soares Costa et al.
JOURNAL OF INORGANIC BIOCHEMISTRY (2019)
Antileishmanial activity of a naphthoquinone derivate against promastigote and amastigote stages of Leishmania infantum and Leishmania amazonensis and its mechanism of action against L-amazonensis species
Debora Vasconcelos Costa Mendonca et al.
PARASITOLOGY RESEARCH (2018)
Improvements to the APBS biomolecular solvation software suite
Elizabeth Jurrus et al.
PROTEIN SCIENCE (2018)
N-Acylhydrazones as drugs
Sreekanth Thota et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2018)
In vitro evaluation of the anti-leishmanial activity and toxicity of PK11195
Carlos Eduardo Sampaio Guedes et al.
MEMORIAS DO INSTITUTO OSWALDO CRUZ (2018)
Cyclic Nucleotide-Specific Phosphodiesterases as Potential Drug Targets for Anti-Leishmania Therapy
Victor Sebastian-Perez et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2018)
Cysteine proteases in protozoan parasites
Jair L. Siqueira-Neto et al.
PLOS NEGLECTED TROPICAL DISEASES (2018)
Potent immunosuppressive activity of a phosphodiesterase-4 inhibitor N-acylhydrazone in models of lipopolysaccharide-induced shock and delayed-type hypersensitivity reaction
Elisalva Teixeira Guimaraes et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2018)
A Nanostructures Lipid System to Improve the Oral Bioavailability of Ruthenium(II) Complexes for the Treatment of Infections Caused by Mycobacterium tuberculosis
Patricia B. da Silva et al.
FRONTIERS IN MICROBIOLOGY (2018)
In vitro evaluation of cytotoxicity and leishmanicidal activity of phthalimido-thiazole derivatives
Amanda Silva dos Santos Alianca et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2017)
Betulinic acid derivative BA5, a dual NF-κB/calcineurin inhibitor, alleviates experimental shock and delayed hypersensitivity
Cassio Santana Meira et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2017)
Drug resistance and treatment failure in leishmaniasis: A 21st century challenge
Alicia Ponte-Sucre et al.
PLOS NEGLECTED TROPICAL DISEASES (2017)
Induction of Early Autophagic Process on Leishmania amazonensis by Synergistic Effect of Miltefosine and Innovative Semi-synthetic Thiosemicarbazone
Debora B. Scariot et al.
FRONTIERS IN MICROBIOLOGY (2017)
Apoptosis-like cell death in Leishmania donovani treated with KalsomeTM10, a new liposomal amphotericin B
Md. Shadab et al.
PLOS ONE (2017)
KH-TFMDI, a novel sirtuin inhibitor, alters the cytoskeleton and mitochondrial metabolism promoting cell death in Leishmania amazonensis
Brunno Renato Farias Vercoza et al.
APOPTOSIS (2017)
Effect of 1,2,3-triazole salts, non-classical bioisosteres of miltefosine, on Leishmania amazonensis
Pedro H. F. Stroppa et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2017)
C5 induces different cell death pathways in promastigotes of Leishmania amazonensis
Edevi Arbonelli Mendes et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2016)
Effects of a novel β-lapachone derivative on Trypanosoma cruzi: Parasite death involving apoptosis, autophagy and necrosis
Danielle Oliveira dos Anjos et al.
INTERNATIONAL JOURNAL FOR PARASITOLOGY-DRUGS AND DRUG RESISTANCE (2016)
New World and Old World Leishmania Infections: A Practical Review
Ines Kevric et al.
DERMATOLOGIC CLINICS (2015)
Novel dialkylphosphorylhydrazones: Synthesis, leishmanicidal evaluation and theoretical investigation of the proposed mechanism of action
Carolina Barbosa Brito da Matta et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2015)
The lysosomotropic drug LeuLeu-OMe induces lysosome disruption and autophagy-independent cell death in Trypanosoma brucei
Hazel Xinyu Koh et al.
MICROBIAL CELL (2015)
N-acylhydrazone derivative ameliorates monocrotaline-induced pulmonary hypertension through the modulation of adenosine AA2R activity
Allan K. N. Alencar et al.
INTERNATIONAL JOURNAL OF CARDIOLOGY (2014)
g_mmpbsa-A GROMACS Tool for High-Throughput MM-PBSA Calculations
Rashmi Kumari et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2014)
Hybrid furoxanyl N-acylhydrazone derivatives as hits for the development of neglected diseases drug candidates
Paola Hernandez et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2013)
Activity of antimalarial drugs in vitro and in a murine model of cutaneous leishmaniasis
Vinicius Pinto Costa Rocha et al.
JOURNAL OF MEDICAL MICROBIOLOGY (2013)
Target identification and mechanism of action in chemical biology and drug discovery
Monica Schenone et al.
NATURE CHEMICAL BIOLOGY (2013)
Autophagy in infection, inflammation and immunity
Vojo Deretic et al.
NATURE REVIEWS IMMUNOLOGY (2013)
Catechol Pyrazolinones as Trypanocidals: Fragment-Based Design, Synthesis, and Pharmacological Evaluation of Nanomolar Inhibitors of Trypanosomal Phosphodiesterase B1
Kristina M. Orrling et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Design, Synthesis, and Pharmacological Evaluation of N-Acylhydrazones and Novel Conformationally Constrained Compounds as Selective and Potent Orally Active Phosphodiesterase-4 Inhibitors
Arthur E. Kuemmerle et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Autophagy in the regulation of pathogen replication and adaptive immunity
Felix Randow et al.
TRENDS IN IMMUNOLOGY (2012)
Systematic review of the adverse effects of cutaneous leishmaniasis treatment in the New World
Luiz F. Oliveira et al.
ACTA TROPICA (2011)
Finding a better path to drug selectivity
Yuko Kawasaki et al.
DRUG DISCOVERY TODAY (2011)
Phosphodiesterase inhibitors as a new generation of antiprotozoan drugs: exploiting the benefit of enzymes that are highly conserved between host and parasite
Thomas Seebeck et al.
FUTURE MEDICINAL CHEMISTRY (2011)
In vitro antileishmanial activity and cytotoxicity of essential oil from Lippia sidoides Cham
Maria das Gracas Freire de Medeiros et al.
PARASITOLOGY INTERNATIONAL (2011)
Microtubule-associated protein 1 light chain 3 alpha (LC3)-associated phagocytosis is required for the efficient clearance of dead cells
Jennifer Martinez et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Synthesis, trypanocidal activity and docking studies of novel quinoxaline-N-acylhydrazones, designed as cruzain inhibitors candidates
Nelilma C. Romeiro et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2009)
Neuropeptides kill African trypanosomes by targeting intracellular compartments and inducing autophagic-like cell death
M. Delgado et al.
CELL DEATH AND DIFFERENTIATION (2009)
Activity of physalins purified from Physalis angulata in in vitro and in vivo models of cutaneous leishmaniasis
Elisalva T. Guimaraes et al.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2009)
Different cell death pathways induced by drugs in Trypanosoma cruzi: An ultrastructural study
Rubem F. S. Menna-Barreto et al.
MICRON (2009)
Naphthoimidazoles promote different death phenotypes in Trypanosoma cruzi
R. F. S. Menna-Barreto et al.
PARASITOLOGY (2009)
Cytotoxic activity screening of some indigenous Thai plants
P. Prayong et al.
FITOTERAPIA (2008)
Crystal structure of the Leishmania major phosphodiesterase LmjPDEB1 and insight into the design of the parasite-selective inhibitors
Huanchen Wang et al.
MOLECULAR MICROBIOLOGY (2007)
Privileged structures: A useful concept for the rational design of new lead drug candidates
Carolina D. Duarte et al.
MINI-REVIEWS IN MEDICINAL CHEMISTRY (2007)
Sterol methenyl transferase inhibitors alter the ultrastructure and function of the Leishmania amazonensis mitochondrion leading to potent growth inhibition
Juliany C. F. Rodrigues et al.
PROTIST (2007)
The Trypanosoma brucei cAMP phosphodiesterases TbrPDEB1 and TbrPDEB2:: flagellar enzymes that are essential for parasite virulence
Michael Oberholzer et al.
FASEB JOURNAL (2007)
Crystal structures of phosphodiesterases and implications on substrate specificity and inhibitor selectivity
Hengming Ke et al.
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2007)
Multiple conformations of phosphodiesterase-5 - Implications for enzyme function and drug development
Huanchen Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Role of interleukin-4 and prostaglandin E2 in Leishmania amazonensis infection of BALB/c mice
Elisalva T. Guimaraes et al.
MICROBES AND INFECTION (2006)
Medicinal chemistry of N-acylhydrazones: New lead-compounds of analgesic, antiinflammatory and antithrombotic drugs
CAM Fraga et al.
CURRENT MEDICINAL CHEMISTRY (2006)
GROMACS: Fast, flexible, and free
D Van der Spoel et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2005)
Crystal structures of phosphodiesterases 4 and 5 in complex with inhibitor 3-isobutyl-1-methylxanthine suggest a conformation determinant of inhibitor selectivity
Q Huai et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Structural basis for the activity of drugs that inhibit phosphodiesterases
GL Card et al.
STRUCTURE (2004)
Induction of autophagic cell death in Leishmania donovani by antimicrobial peptides
A Bera et al.
MOLECULAR AND BIOCHEMICAL PARASITOLOGY (2003)
Cell biology of Leishmania spp.: Invading and evading
MA Vannier-Santos et al.
CURRENT PHARMACEUTICAL DESIGN (2002)
Electrostatics of nanosystems: Application to microtubules and the ribosome
NA Baker et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
A new paradigm for parallel adaptive meshing algorithms
RE Bank et al.
SIAM JOURNAL ON SCIENTIFIC COMPUTING (2000)
A possible molecular mechanism for the inhibition of cysteine proteases by salicylaldehyde N-acylhydrazones and related compounds
DR Ifa et al.
JOURNAL OF MOLECULAR STRUCTURE-THEOCHEM (2000)