相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Neuroprotective Effects of Ethyl Pyruvate against Aluminum Chloride-Induced Alzheimer's Disease in Rats via Inhibiting Toll-Like Receptor 4
Vijaya Durga Chavali et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2020)
Inhibition of TLR4 Induces M2 Microglial Polarization and Provides Neuroprotection via the NLRP3 Inflammasome in Alzheimer's Disease
Weigang Cui et al.
FRONTIERS IN NEUROSCIENCE (2020)
Oral Administration of Alpha Linoleic Acid Rescues Aβ-Induced Glia-Mediated Neuroinflammation and Cognitive Dysfunction in C57BL/6N Mice
Waqar Ali et al.
CELLS (2020)
Alzheimer's-associated PLCγ2 is a signaling node required for both TREM2 function and the inflammatory response in human microglia
Benjamin J. Andreone et al.
NATURE NEUROSCIENCE (2020)
Therapeutic Trem2 activation ameliorates amyloid-beta deposition and improves cognition in the 5XFAD model of amyloid deposition
Brittani R. Price et al.
JOURNAL OF NEUROINFLAMMATION (2020)
Baicalin mitigates cognitive impairment and protects neurons from microglia-mediated neuroinflammation via suppressing NLRP3 inflammasomes and TLR4/NF-κB signaling pathway
Xin Jin et al.
CNS NEUROSCIENCE & THERAPEUTICS (2019)
HMGB1 gene silencing inhibits neuroinflammation via down-regulation of NF-κB signaling in primary hippocampal neurons induced by Aβ25-35
Ke Nan et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2019)
CD14 and Toll-Like Receptor 4 Promote Fibrillar A beta(42) Uptake by Microglia Through A Clathrin-Mediated Pathway
Mai Fujikura et al.
JOURNAL OF ALZHEIMERS DISEASE (2019)
Hesperetin Confers Neuroprotection by Regulating Nrf2/TLR4/NF-κB Signaling in an Aβ Mouse Model
Muhammad Ikram et al.
MOLECULAR NEUROBIOLOGY (2019)
Imbalance of Microglial TLR4/TREM2 in LPS-Treated APP/PS1 Transgenic Mice: A Potential Link Between Alzheimer's Disease and Systemic Inflammation
Jian Zhou et al.
NEUROCHEMICAL RESEARCH (2019)
Soluble TREM2 ameliorates pathological phenotypes by modulating microglial functions in an Alzheimer's disease model
Li Zhong et al.
NATURE COMMUNICATIONS (2019)
TREM2 Attenuates Aβ1-42-Mediated Neuroinflammation in BV-2 Cells by Downregulating TLR Signaling
Huiping Long et al.
NEUROCHEMICAL RESEARCH (2019)
Association of TLR4 with Alzheimer's disease risk and presymptomatic biomarkers of inflammation
Justin Miron et al.
ALZHEIMERS & DEMENTIA (2019)
Prestimulation of Microglia Through TLR4 Pathway Promotes Interferon Beta Expression in a Rat Model of Alzheimer's Disease
Niloufar Yousefi et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2019)
2019 Alzheimer's disease facts and figures
Joseph Gaugler et al.
ALZHEIMERS & DEMENTIA (2019)
Microglia in Alzheimer's disease
David V. Hansen et al.
JOURNAL OF CELL BIOLOGY (2018)
Thymoquinone alleviates the experimentally induced Alzheimer's disease inflammation by modulation of TLRs signaling
Y. S. Abulfadl et al.
HUMAN & EXPERIMENTAL TOXICOLOGY (2018)
Atorvastatin Attenuates Cognitive Deficits and Neuroinflammation Induced by A beta(1-42) Involving Modulation of TLR4/TRAF6/NF-kappa B Pathway
Shan Wang et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2018)
Early minor stimulation of microglial TLR2 and TLR4 receptors attenuates Alzheimer's disease-related cognitive deficit in rats: behavioral, molecular, and electrophysiological evidence
Hamid Gholami Pourbadie et al.
NEUROBIOLOGY OF AGING (2018)
Interplay between innate immunity and Alzheimer disease: APOE and TREM2 in the spotlight
Yang Shi et al.
NATURE REVIEWS IMMUNOLOGY (2018)
The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases
Susanne Krasemann et al.
IMMUNITY (2017)
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease
Rebecca Sims et al.
NATURE GENETICS (2017)
Lipopolysaccharide-Induced Memory Impairment in Rats: a Model of Alzheimer's Disease
R. Zakaria et al.
PHYSIOLOGICAL RESEARCH (2017)
The role of the immune system in Alzheimer disease: Etiology and treatment
Stefan Jevtic et al.
AGEING RESEARCH REVIEWS (2017)
A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease
Hadas Keren-Shaul et al.
CELL (2017)
Toll-like receptor 4-dependent glial cell activation mediates the impairment in memory establishment induced by β-amyloid oligomers in an acute mouse model of Alzheimer's disease
Claudia Balducci et al.
BRAIN BEHAVIOR AND IMMUNITY (2017)
Microglial response to LPS increases in wild-type mice during aging but diminishes in an Alzheimer's mouse model: Implication of TLR4 signaling in disease progression
Michelle Go et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2016)
Microglial toll-like receptors and Alzheimer's disease
Fan Su et al.
BRAIN BEHAVIOR AND IMMUNITY (2016)
Gx-50 reduces β-amyloid-induced TNF-α, IL-1β, NO, and PGE2 expression and inhibits NF-κB signaling in a mouse model of Alzheimer's disease
Shi Shi et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2016)
Chotosan improves Aβ1-42-induced cognitive impairment and neuroinflammatory and apoptotic responses through the inhibition of TLR-4/NF-κB signaling in mice
Lei Chen et al.
JOURNAL OF ETHNOPHARMACOLOGY (2016)
Inducible nitric oxide inhibitor aminoguanidine, ameliorates deleterious effects of lipopolysaccharide on memory and long term potentiation in rat
Akbar Anaeigoudari et al.
LIFE SCIENCES (2016)
TREM2 Binds to Apolipoproteins, Including APOE and CLU/APOJ, and Thereby Facilitates Uptake of Amyloid-Beta by Microglia
Felix L. Yeh et al.
NEURON (2016)
HMGB1, a pathogenic molecule that induces neurite degeneration via TLR4-MARCKS, is a potential therapeutic target for Alzheimer's disease
Kyota Fujita et al.
SCIENTIFIC REPORTS (2016)
Prostaglandin E2 Receptor Subtype 2 Regulation of Scavenger Receptor CD36 Modulates Microglial Aβ42 Phagocytosis
Xianwu Li et al.
AMERICAN JOURNAL OF PATHOLOGY (2015)
Alzheimer's Disease Risk Genes and Mechanisms of Disease Pathogenesis
Celeste M. Karch et al.
BIOLOGICAL PSYCHIATRY (2015)
Apolipoprotein E Is a Ligand for Triggering Receptor Expressed on Myeloid Cells 2 (TREM2)
Yuka Atagi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
APOε4 is associated with enhanced in vivo innate immune responses in human subjects
Stephen C. Gale et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2014)
Correlated Inflammatory Responses and Neurodegeneration in Peptide-Injected Animal Models of Alzheimer's Disease
James G. McLarnon
BIOMED RESEARCH INTERNATIONAL (2014)
Toll-like receptor signaling pathways
Takumi Kawasaki et al.
FRONTIERS IN IMMUNOLOGY (2014)
TREM2 Variants in Alzheimer's Disease
Rita Guerreiro et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
Toll-like receptor 4 stimulation with the detoxified ligand monophosphoryl lipid A improves Alzheimer's disease-related pathology
Jean-Philippe Michaud et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Pathogenesis and Disease-modifying Therapy in Alzheimer's Disease: The Flat Line of Progress
Rudy J. Castellani et al.
ARCHIVES OF MEDICAL RESEARCH (2012)
Common Variants in Toll-Like Receptor 4 Confer Susceptibility to Alzheimer's Disease in a Han Chinese Population
Jin-Tai Yu et al.
CURRENT ALZHEIMER RESEARCH (2012)
TREM-2, triggering receptor expressed on myeloid cell-2, negatively regulates TLR responses in dendritic cells
Hiroaki Ito et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2012)
Sequence Variants of Toll Like Receptor 4 and Late-Onset Alzheimer's Disease
Yen-Ching Chen et al.
PLOS ONE (2012)
Genetic association of TLR4/11367 polymorphism with late-onset Alzheimer's disease in a Han Chinese population
Li-Zhu Wang et al.
BRAIN RESEARCH (2011)
Toll-like receptors
Eva Marie Y. Moresco et al.
CURRENT BIOLOGY (2011)
High-mobility group box-1 impairs memory in mice through both toll-like receptor 4 and Receptor for Advanced Glycation End Products
Andrey Mazarati et al.
EXPERIMENTAL NEUROLOGY (2011)
Soybean isoflavone alleviates β-amyloid 1-42 induced inflammatory response to improve learning and memory ability by down regulation of Toll-like receptor 4 expression and nuclear factor-κB activity in rats
B. J. Ding et al.
INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE (2011)
TLR4 mutation reduces microglial activation, increases Aβ deposits and exacerbates cognitive deficits in a mouse model of Alzheimer's disease
Min Song et al.
JOURNAL OF NEUROINFLAMMATION (2011)
Apolipoprotein E inhibits Toll-like receptor (TLR)-3-and TLR-4-mediated macrophage activation through distinct mechanisms
Yanjuan Zhu et al.
BIOCHEMICAL JOURNAL (2010)
The Genetics of Alzheimer Disease: Back to the Future
Lars Bertram et al.
NEURON (2010)
MECHANISMS OF DISEASE Alzheimer's Disease
Henry W. Querfurth et al.
NEW ENGLAND JOURNAL OF MEDICINE (2010)
MyD88-independent activation of a novel actin-Cdc42/Rac pathway is required for Toll-like receptor-stimulated phagocytosis
Ling Kong et al.
CELL RESEARCH (2008)
Toll-like receptor 4-dependent upregulation of cytokines in a transgenic mouse model of Alzheimer's disease
Jing-Ji Jin et al.
JOURNAL OF NEUROINFLAMMATION (2008)
Role of the toll-like receptor 4 in neuro-inflammation in Alzheimer's disease
Silke Walter et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2007)
Role of toll-like receptor signalling in Aβ uptake and clearance
Kazuki Tahara et al.
BRAIN (2006)
Apolipoprotein E structure: insights into function
Danny M. Hatters et al.
TRENDS IN BIOCHEMICAL SCIENCES (2006)
Pathogen recognition and innate immunity
S Akira et al.
CELL (2006)
Effect of the functional toll-like receptor 4 Asp299Gly polymorphism on susceptibility to late-onset Alzheimer's disease
P Minoretti et al.
NEUROSCIENCE LETTERS (2006)
Toll-like receptors induce a phagocytic gene program through p38
SE Doyle et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2004)
Microglia initiate central nervous system innate and adaptive immune responses through multiple TLRs
JK Olson et al.
JOURNAL OF IMMUNOLOGY (2004)
Cultured astrocytes express toll-like receptors for bacterial products
CC Bowman et al.
GLIA (2003)
Role of high mobility group protein-1 (HMG1) in amyloid-β homeostasis
K Takata et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
Broad expression of Toll-like receptors in the human central nervous system
M Bsibsi et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2002)
Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
P Scaffidi et al.
NATURE (2002)
Inflammatory factors are elevated in brain microvessels in Alzheimer's disease
P Grammas et al.
NEUROBIOLOGY OF AGING (2001)
分享论文
