4.6 Review

The Molecular and Microenvironmental Landscape of Glioblastomas: Implications for the Novel Treatment Choices

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Immunology

Tumour-intrinsic resistance to immune checkpoint blockade

Anusha Kalbasi et al.

NATURE REVIEWS IMMUNOLOGY (2020)

Review Biotechnology & Applied Microbiology

Epigenetic regulation of DNA repair genes and implications for tumor therapy

Markus Christmann et al.

MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH (2019)

Review Clinical Neurology

The landscape of the mesenchymal signature in brain tumours

Jinan Behnan et al.

Article Biochemistry & Molecular Biology

Neoadjuvant nivolumab modifies the tumor immune microenvironment in resectable glioblastoma

Kurt A. Schalper et al.

NATURE MEDICINE (2019)

Article Biochemistry & Molecular Biology

Immune and genomic correlates of response to anti-PD-1 immunotherapy in glioblastoma

Junfei Zhao et al.

NATURE MEDICINE (2019)

Review Cell Biology

The multiple mechanisms that regulate p53 activity and cell fate

Antonina Hafner et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2019)

Review Oncology

The Role of SVZ Stem Cells in Glioblastoma

Christine Altmann et al.

CANCERS (2019)

Article Multidisciplinary Sciences

Combination anti-CTLA-4 plus anti-PD-1 checkpoint blockade utilizes cellular mechanisms partially distinct from monotherapies

Spencer C. Wei et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

Review Biochemistry & Molecular Biology

Mutant p53 as a guardian of the cancer cell

Fiamma Mantovani et al.

CELL DEATH AND DIFFERENTIATION (2019)

Article Oncology

Genetic, Epigenetic, and Immunologic Profiling of MMR-Deficient Relapsed Glioblastoma

Stefano Indraccolo et al.

CLINICAL CANCER RESEARCH (2019)

Article Multidisciplinary Sciences

Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial

Derin B. Keskin et al.

NATURE (2019)

Article Biochemistry & Molecular Biology

The molecular landscape of glioma in patients with Neurofibromatosis 1

Fulvio D'Angelo et al.

NATURE MEDICINE (2019)

Review Oncology

Glioblastoma: Microenvironment and Niche Concept

Davide Schiffer et al.

CANCERS (2019)

Article Biochemistry & Molecular Biology

Up-regulation of MSH6 is associated with temozolomide resistance in human glioblastoma

Quanye Sun et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018)

Review Oncology

Immune checkpoint therapy in liver cancer

Feng Xu et al.

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2018)

Article Clinical Neurology

Targetable Gene Fusions Associate With the IDH Wild-Type Astrocytic Lineage in Adult Gliomas

Sherise D. Ferguson et al.

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2018)

Article Medicine, General & Internal

Tisagenlecleucel in Children and Young Adults with B-Cell Lymphoblastic Leukemia

S. L. Maude et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

Review Biochemistry & Molecular Biology

Exploring Long Noncoding RNAs in Glioblastoma: Regulatory Mechanisms and Clinical Potentials

Tao Zeng et al.

INTERNATIONAL JOURNAL OF GENOMICS (2018)

Review Immunology

Immune Microenvironment in Glioblastoma Subtypes

Zhihong Chen et al.

FRONTIERS IN IMMUNOLOGY (2018)

Meeting Abstract Oncology

Phase II study of pembrolizumab or pembrolizumab plus bevacizumab for recurrent glioblastoma (rGBM) patients

David A. Reardon et al.

JOURNAL OF CLINICAL ONCOLOGY (2018)

Article Oncology

Phase-2 trial of palbociclib in adult patients with recurrent RB1-positive glioblastoma

Jennie W. Taylor et al.

JOURNAL OF NEURO-ONCOLOGY (2018)

Review Oncology

Fundamental Mechanisms of Immune Checkpoint Blockade Therapy

Spencer C. Wei et al.

CANCER DISCOVERY (2018)

Review Oncology

The p53 Pathway in Glioblastoma

Ying Zhang et al.

CANCERS (2018)

Article Oncology

BRAF Inhibition in BRAFV600-Mutant Gliomas: Results From the VE-BASKET Study

Thomas Kaley et al.

JOURNAL OF CLINICAL ONCOLOGY (2018)

Article Multidisciplinary Sciences

Drug and disease signature integration identifies synergistic combinations in glioblastoma

Vasileios Stathias et al.

NATURE COMMUNICATIONS (2018)

Review Pharmacology & Pharmacy

Targeted Theranostic Nanoparticles for Brain Tumor Treatment

Maria Mendes et al.

PHARMACEUTICS (2018)

Review Oncology

Immunotherapy of Hepatocellular Carcinoma: Facts and Hopes

Mercedes Inarrairaegui et al.

CLINICAL CANCER RESEARCH (2018)

Review Clinical Neurology

Treatment of glioblastoma in adults

Wolfgang Wick et al.

THERAPEUTIC ADVANCES IN NEUROLOGICAL DISORDERS (2018)

Article Biochemistry & Molecular Biology

Distinctive Patterns of Transcription and RNA Processing for Human lincRNAs

Margarita Schlackow et al.

MOLECULAR CELL (2017)

Article Oncology

Correlation of immune phenotype with IDH mutation in diffuse glioma

Anna Sophie Berghoff et al.

NEURO-ONCOLOGY (2017)

Article Medicine, General & Internal

Axicabtagene Ciloleucel CAR T-Cell Therapy in Refractory Large B-Cell Lymphoma

S. S. Neelapu et al.

NEW ENGLAND JOURNAL OF MEDICINE (2017)

Article Multidisciplinary Sciences

Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade

Dung T. Le et al.

SCIENCE (2017)

Review Immunology

T Cell Exhaustion in Glioblastoma: Intricacies of Immune Checkpoints

Reza Mirzaei et al.

TRENDS IN IMMUNOLOGY (2017)

Article Multidisciplinary Sciences

The long non-coding RNA LOC441204 enhances cell growth in human glioma

Tzu-Kang Lin et al.

SCIENTIFIC REPORTS (2017)

Article Multidisciplinary Sciences

A TCR-based Chimeric Antigen Receptor

Even Waiseng et al.

SCIENTIFIC REPORTS (2017)

Article Biochemistry & Molecular Biology

Distinct Cellular Mechanisms Underlie Anti-CTLA-4 and Anti-PD-1 Checkpoint Blockade

Spencer C. Wei et al.

Article Oncology

The Microenvironmental Landscape of Brain Tumors

Daniela F. Quail et al.

CANCER CELL (2017)

Review Immunology

The movers and shapers in immune privilege of the CNS

Britta Engelhardt et al.

NATURE IMMUNOLOGY (2017)

Article Oncology

Loss of PTEN Promotes Resistance to T Cell-Mediated Immunotherapy

Weiyi Peng et al.

CANCER DISCOVERY (2016)

Article Oncology

RECIST 1.1-Update and clarification: From the RECIST committee

Lawrence H. Schwartz et al.

EUROPEAN JOURNAL OF CANCER (2016)

Review Biotechnology & Applied Microbiology

DNA repair mechanisms and their clinical impact in glioblastoma

Helene Erasimus et al.

MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH (2016)

Article Genetics & Heredity

Clonal evolution of glioblastoma under therapy

Jiguang Wang et al.

NATURE GENETICS (2016)

Article Immunology

Origin, fate and dynamics of macrophages at central nervous system interfaces

Tobias Goldmann et al.

NATURE IMMUNOLOGY (2016)

Article Biochemistry & Molecular Biology

Recurrent MET fusion genes represent a drug target in pediatric glioblastoma

Sebastian Bender et al.

NATURE MEDICINE (2016)

Editorial Material Oncology

In search of a target: PD-1 and PD-L1 profiling across glioma types

Anna S. Berghoff et al.

NEURO-ONCOLOGY (2016)

Article Medicine, General & Internal

Regression of Glioblastoma after Chimeric Antigen Receptor T-Cell Therapy

Christine E. Brown et al.

NEW ENGLAND JOURNAL OF MEDICINE (2016)

Article Medicine, General & Internal

Pembrolizumab versus Chemotherapy for PD-L1-Positive Non-Small-Cell Lung Cancer

Martin Reck et al.

NEW ENGLAND JOURNAL OF MEDICINE (2016)

Article Neurosciences

NPAS3 Regulates Transcription and Expression of VGF: Implications for Neurogenesis and Psychiatric Disorders

Dongxue Yang et al.

FRONTIERS IN MOLECULAR NEUROSCIENCE (2016)

Editorial Material Oncology

Biomarkers in Cancer Immunotherapy

Ton N. Schumacher et al.

CANCER CELL (2015)

Article Oncology

Detection, Characterization, and Inhibition of FGFR-TACC Fusions in IDH Wild-type Glioma

Anna Luisa Di Stefano et al.

CLINICAL CANCER RESEARCH (2015)

Review Pharmacology & Pharmacy

Overcoming the blood-brain tumor barrier for effective glioblastoma treatment

O. van Tellingen et al.

DRUG RESISTANCE UPDATES (2015)

Article Oncology

EGFR Amplified and Overexpressing Glioblastomas and Association With Better Response to Adjuvant Metronomic Temozolomide

Manuela Cominelli et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2015)

Article Oncology

Impact of a New Fusion Receptor on PD-1-Mediated Immunosuppression in Adoptive T Cell Therapy

Sebastian Kobold et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2015)

Article Clinical Neurology

LRP1B deletion is associated with poor outcome for glioblastoma patients

E. Tabouret et al.

JOURNAL OF THE NEUROLOGICAL SCIENCES (2015)

Article Multidisciplinary Sciences

Structural and functional features of central nervous system lymphatic vessels

Antoine Louveau et al.

NATURE (2015)

Article Medicine, General & Internal

PD-1 Blockade with Nivolumab in Relapsed or Refractory Hodgkin's Lymphoma

Stephen M. Ansell et al.

NEW ENGLAND JOURNAL OF MEDICINE (2015)

Article Medicine, General & Internal

Nivolumab versus Everolimus in Advanced Renal-Cell Carcinoma

R. J. Motzer et al.

NEW ENGLAND JOURNAL OF MEDICINE (2015)

Article Medicine, General & Internal

Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma

J. Larkin et al.

NEW ENGLAND JOURNAL OF MEDICINE (2015)

Article Multidisciplinary Sciences

Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer

Naiyer A. Rizvi et al.

SCIENCE (2015)

Article Oncology

EGFR Amplified and Overexpressing Glioblastomas and Association With Better Response to Adjuvant Metronomic Temozolomide

Manuela Cominelli et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2015)

Article Oncology

Impact of a New Fusion Receptor on PD-1-Mediated Immunosuppression in Adoptive T Cell Therapy

Sebastian Kobold et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2015)

Review Oncology

Immunosuppressive mechanisms of malignant gliomas: parallels at non-CNS sites

Powell Perng et al.

FRONTIERS IN ONCOLOGY (2015)

Review Oncology

Glioblastoma: Defining Tumor Niches

Dolores Hambardzumyan et al.

TRENDS IN CANCER (2015)

Article Engineering, Biomedical

Hyaluronan: A simple polysaccharide with diverse biological functions

Kevin T. Dicker et al.

ACTA BIOMATERIALIA (2014)

Article Biochemistry & Molecular Biology

CRNDE, a long non-coding RNA responsive to insulin/IGF signaling, regulates genes involved in central metabolism

Blake C. Ellis et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2014)

Article Genetics & Heredity

Analysis of DNA repair gene polymorphisms in glioblastoma

Irene Rodriguez-Hernandez et al.

Review Clinical Neurology

MGMT testing-the challenges for biomarker-based glioma treatment

Wolfgang Wick et al.

NATURE REVIEWS NEUROLOGY (2014)

Review Oncology

Immunotherapy advances for glioblastoma

David A. Reardon et al.

NEURO-ONCOLOGY (2014)

Review Oncology

Molecular Heterogeneity of Glioblastoma and its Clinical Relevance

Katalin Eder et al.

PATHOLOGY & ONCOLOGY RESEARCH (2014)

Article Radiology, Nuclear Medicine & Medical Imaging

Patterns of relapse in glioblastoma multiforme following concomitant chemoradiotherapy with temozolomide

J. Sherriff et al.

BRITISH JOURNAL OF RADIOLOGY (2013)

Article Biochemistry & Molecular Biology

The Somatic Genomic Landscape of Glioblastoma

Cameron W. Brennan et al.

Review Oncology

The Definition of Primary and Secondary Glioblastoma

Hiroko Ohgaki et al.

CLINICAL CANCER RESEARCH (2013)

Article Biochemistry & Molecular Biology

Structure and Interactions of the Human Programmed Cell Death 1 Receptor

Xiaoxiao Cheng et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Review Biochemistry & Molecular Biology

Microenvironmental regulation of tumor progression and metastasis

Daniela F. Quail et al.

NATURE MEDICINE (2013)

Editorial Material Oncology

BRAIN CANCER IN 2012 Molecular characterization leads the way

Roger Stupp et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2013)

Review Pharmacology & Pharmacy

Modern methods for delivery of drugs across the blood-brain barrier

Yan Chen et al.

ADVANCED DRUG DELIVERY REVIEWS (2012)

Article Oncology

Molecular characteristics of glioblastoma with 1p/19q co-deletion

Masahiro Mizoguchi et al.

BRAIN TUMOR PATHOLOGY (2012)

Editorial Material Oncology

The Quest for Self-Identity: Not All Cancer Stem Cells Are the Same

Anita B. Hjelmeland et al.

CLINICAL CANCER RESEARCH (2012)

Review Cell Biology

Emerging insights into the molecular and cellular basis of glioblastoma

Gavin P. Dunn et al.

GENES & DEVELOPMENT (2012)

Article Oncology

Predictive impact of MGMT promoter methylation in glioblastoma of the elderly

Guido Reifenberger et al.

INTERNATIONAL JOURNAL OF CANCER (2012)

Review Oncology

Interstitial guidance of cancer invasion

Pavlo G. Gritsenko et al.

JOURNAL OF PATHOLOGY (2012)

Article Biochemistry & Molecular Biology

Tumor PD-L1 co-stimulates primary human CD8+ cytotoxic T cells modified to express a PD1:CD28 chimeric receptor

Megan E. Prosser et al.

MOLECULAR IMMUNOLOGY (2012)

Article Multidisciplinary Sciences

Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

Jeremy Schwartzentruber et al.

NATURE (2012)

Article Multidisciplinary Sciences

Transforming Fusions of FGFR and TACC Genes in Human Glioblastoma

Devendra Singh et al.

SCIENCE (2012)

Article Pathology

NPAS3 Demonstrates Features of a Tumor Suppressive Role in Driving the Progression of Astrocytomas

Frederico Moreira et al.

AMERICAN JOURNAL OF PATHOLOGY (2011)

Review Biochemistry & Molecular Biology

Hallmarks of Cancer: The Next Generation

Douglas Hanahan et al.

Review Immunology

The PD-1 pathway in tolerance and autoimmunity

Loise M. Francisco et al.

IMMUNOLOGICAL REVIEWS (2010)

Article Oncology

Salvage therapy with single agent bevacizumab for recurrent glioblastoma

Marc C. Chamberlain et al.

JOURNAL OF NEURO-ONCOLOGY (2010)

Review Biochemistry & Molecular Biology

The blood-brain barrier in brain homeostasis and neurological diseases

Nicolas Weiss et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2009)

Article Oncology

Bevacizumab Alone and in Combination With Irinotecan in Recurrent Glioblastoma

Henry S. Friedman et al.

JOURNAL OF CLINICAL ONCOLOGY (2009)

Article Multidisciplinary Sciences

Association of reactive oxygen species levels and radioresistance in cancer stem cells

Maximilian Diehn et al.

NATURE (2009)

Article Public, Environmental & Occupational Health

Promoter Methylation and Polymorphisms of the MGMT Gene in Glioblastomas: A Population-Based Study

Izabela Zawlik et al.

NEUROEPIDEMIOLOGY (2009)

Review Clinical Neurology

The interface between glial progenitors and gliomas

Peter Canoll et al.

ACTA NEUROPATHOLOGICA (2008)

Review Cell Biology

Extracellular matrix of the central nervous system: from neglect to challenge

Dieter R. Zimmermann et al.

HISTOCHEMISTRY AND CELL BIOLOGY (2008)

Review Oncology

Survival of the fittest: Cancer stem cells in therapeutic resistance and angiogenesis

Christine E. Eyler et al.

JOURNAL OF CLINICAL ONCOLOGY (2008)

Article Multidisciplinary Sciences

An integrated genomic analysis of human glioblastoma Multiforme

D. Williams Parsons et al.

SCIENCE (2008)

Article Multidisciplinary Sciences

Patterns of somatic mutation in human cancer genomes

Christopher Greenman et al.

NATURE (2007)

Article Oncology

A perivascular niche for brain tumor stem cells

Christopher Calabrese et al.

CANCER CELL (2007)

Article Oncology

Phase II study of CCI-779 in patients with recurrent glioblastoma multiforme

SM Chang et al.

INVESTIGATIONAL NEW DRUGS (2005)

Article Medicine, General & Internal

MGMT gene silencing and benefit from temozolomide in glioblastoma

ME Hegi et al.

NEW ENGLAND JOURNAL OF MEDICINE (2005)

Article Medicine, General & Internal

Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

R Stupp et al.

NEW ENGLAND JOURNAL OF MEDICINE (2005)

Article Clinical Neurology

Expression of extracellular matrix components in a highly infiltrative in vivo glioma model

R Mahesparan et al.

ACTA NEUROPATHOLOGICA (2003)

Review Cell Biology

CD44: From adhesion molecules to signalling regulators

H Ponta et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2003)

Article Oncology

Hyaluronate receptors mediating glioma cell migration and proliferation

Y Akiyama et al.

JOURNAL OF NEURO-ONCOLOGY (2001)

Review Endocrinology & Metabolism

Anti-inflammatory cytokines: Expression and action in the brain

L Vitkovic et al.

NEUROIMMUNOMODULATION (2001)

Article Medicine, General & Internal

Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents

M Esteller et al.

NEW ENGLAND JOURNAL OF MEDICINE (2000)

Review Clinical Neurology

Extracellular matrix and the brain: components and function

U Novak et al.

JOURNAL OF CLINICAL NEUROSCIENCE (2000)