4.3 Editorial Material

An update on the complex relationship between clozapine and pneumonia

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Summary: This study compared pharmacokinetic parameters between clozapine-treated patients with and without hypersalivation from a large therapeutic drug monitoring database. Patients with hypersalivation had higher clozapine plasma concentrations and concentrations-by-dose. Potential role for therapeutic drug monitoring in the prevention or management of clozapine-related hypersalivation is suggested based on the findings.

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