期刊
SAUDI JOURNAL OF BIOLOGICAL SCIENCES
卷 28, 期 4, 页码 2267-2271出版社
ELSEVIER
DOI: 10.1016/j.sjbs.2021.01.019
关键词
Pollution; Cirrhinus mrigala; Nephrotoxicity; Textile dye; Hematoxylin
类别
资金
- Ministry of Educationsin Saudi Arabia [IFKSURG-1435-012]
The cytotoxicity of different industrial dyes in industrial effluents on freshwater fishes is a major global issue. This study evaluated the toxic effects of hematoxylin dye on the kidneys of Cirrhinus mrigala, showing significant tissue damage and reduced fish growth in lower concentrations of the dye. Hematoxylin, despite its wide range of applications, can be highly toxic to aquatic fauna even in small amounts released into effluents.
The cytotoxicity in freshwater fishes due to different industrial dyes in industrial effluents is a major worldwide issue. Hematoxylin dye has a wide range of uses in textile industries and laboratories. This study was aimed to evaluate the toxic effects of hematoxylin's sublethal effect in vitro in Cirrhinus mrigala. The fish was exposed to different grading concentrations of dye in the aquarium. Fish were sacrificed and dissected to remove the kidney after exposure to hematoxylin dye for specific time intervals. Nephrotoxicity and cytotoxicity induced by this dye were detected through histopathology by using the paraffin wax method. Immediate mortality of fish was noticed against the exposure to 0.08 g/L (LC50) concentration of dye, but at 0.008 mg/L and 0.018 mg/L, it showed tremendous tissue damage in the kidneys, significant reduction in fish growth. This dye induced many alterations in the kidney such as tubular degeneration, vacuolation, shrinkage of a glomerulus, reduced lumen, congestion in the kidney, glomerulonephritis, absence of Bowmen space, necrosis of the hematopoietic interstitial tissues, clogging of tubules, necrosis in the glomerulus and increased space between glomerulus and bowmen's capsule. Although this dye has a wide range of biological and industrial applications, a minute amount of hematoxylin released in effluents is quite toxic to aquatic fauna. (C) 2021 The Author(s). Published by Elsevier B.V. on behalf of King Saud University.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据