4.7 Review

Aflatoxin Detoxification Using Microorganisms and Enzymes

期刊

TOXINS
卷 13, 期 1, 页码 -

出版社

MDPI
DOI: 10.3390/toxins13010046

关键词

aflatoxin; biological detoxification; detoxification mechanism; degradation products; probiotics

资金

  1. National Natural Science Foundation of China [31972746, 31772809, 31872538]
  2. Liaoning Provincial Natural Fund Guidance Program Project [2019-ZD-0708]
  3. China Postdoctoral Science Foundation [2016T90477]
  4. PAPD
  5. Project UHK VT2019-2021

向作者/读者索取更多资源

The article mainly discusses the serious threat of aflatoxin to the food and feed industry and human health, explores the application of biological methods in dealing with aflatoxin, and focuses on the research of microorganisms with detoxification effects and their detoxification mechanisms.
Mycotoxin contamination causes significant economic loss to food and feed industries and seriously threatens human health. Aflatoxins (AFs) are one of the most harmful mycotoxins, which are produced by Aspergillus flavus, Aspergillus parasiticus, and other fungi that are commonly found in the production and preservation of grain and feed. AFs can cause harm to animal and human health due to their toxic (carcinogenic, teratogenic, and mutagenic) effects. How to remove AF has become a major problem: biological methods cause no contamination, have high specificity, and work at high temperature, affording environmental protection. In the present research, microorganisms with detoxification effects researched in recent years are reviewed, the detoxification mechanism of microbes on AFs, the safety of degrading enzymes and reaction products formed in the degradation process, and the application of microorganisms as detoxification strategies for AFs were investigated. One of the main aims of the work is to provide a reliable reference strategy for biological detoxification of AFs.

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