Observational study on effect of lock down due to COVID 19 on HBA1c levels in patients with diabetes: Experience from Central India

Background and aims: Diabetes is a chronic metabolic condition characterized by hyperglycemia and is associated with several complications. Prevalence of Diabetes in adult population in India ranges from 10.9 to 14.2% in urban area and 3.0-7.8% in rural area. Glycemic control is an important factor in preventing the complications associated with diabetes. HBA1c is the indicator of long-term glycemic control and slight variation in it significantly alters the risk of diabetic complications. Thus, the aim of this study was to study the change in HBA1c levels due to lock down in patients with diabetes.Methods: 307 patients with diabetes who had attended our endocrine OPD in last 3 months before nation-wide 68 days lockdown from 24 March 2020 to 31 May 2020, and had recent HBA1c report in past and willing to participate were included in the study after informed consent from 2nd June 2020 to 14th June 2020 when first phase of Unlock started, to identify the change in HBA1c levels during the lockdown period in our patients with diabetes.Results: The patients were aged between 25-69 years and male to female ratio was 181:126 (1.44: 1). The mean age and mean duration of diabetes in our patients was 55.68 years and 7.95 years respectively. Increment of 0.51% was seen in mean HBA1c levels in our patient from 7.92% mean pre-lockdown HBA1c to mean of 8.43% after release of lock down.Conclusion: Glycemic control got deranged during lockdown period with significant increase of mean HBA1c by 0.51% in immediate post lock down period which may significantly increase the annual inci-dence of complications related to diabetes.(c) 2020 Primary Care Diabetes Europe. Published by Elsevier Ltd. All rights reserved.

Automated summary

The study aimed to investigate the change in HBA1c levels in patients with diabetes due to the lockdown. There was a significant increase in the average HBA1c levels in diabetic patients during the lockdown period.