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Jennifer E. Below et al.
SCIENTIFIC REPORTS (2016)
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Mariet Allen et al.
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Casey S. Greene et al.
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Mark D. M. Leiserson et al.
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Damian Szklarczyk et al.
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Raul Gonzalez-Dominguez et al.
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Chia-Yen Chen et al.
BIOINFORMATICS (2013)
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Matan Hofree et al.
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David H. Margolin et al.
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Rita Guerreiro et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
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U. Martin Singh-Blom et al.
PLOS ONE (2013)
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R. Kaddurah-Daouk et al.
TRANSLATIONAL PSYCHIATRY (2013)
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Christof Winter et al.
PLOS COMPUTATIONAL BIOLOGY (2012)
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Oron Vanunu et al.
PLOS COMPUTATIONAL BIOLOGY (2010)
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
A Subramanian et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
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ZH Wu et al.
NATURE MEDICINE (2005)
Incipient Alzheimer's disease: Microarray correlation analyses reveal major transcriptional and tumor suppressor responses
EM Blalock et al.
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MR Hynd et al.
NEUROCHEMISTRY INTERNATIONAL (2004)
Neurotoxicity induces cleavage of p35 to p25 by calpain
MS Lee et al.
NATURE (2000)