相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。A new coronavirus associated with human respiratory disease in China
Fan Wu et al.
NATURE (2020)
Therapeutic options for the 2019 novel coronavirus (2019-nCoV)
Guangdi Li et al.
NATURE REVIEWS DRUG DISCOVERY (2020)
Charting the Fragmented Landscape of Drug Synergy
Christian T. Meyer et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2020)
Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses
Michael Letko et al.
NATURE MICROBIOLOGY (2020)
SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
Markus Hoffmann et al.
CELL (2020)
Enhanced isolation of SARS-CoV-2 by TMPRSS2-expressing cells
Shutoku Matsuyama et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Characterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV
Xiuyuan Ou et al.
NATURE COMMUNICATIONS (2020)
Research and Development on Therapeutic Agents and Vaccines for COVID-19 and Related Human Coronavirus Diseases
Cynthia Liu et al.
ACS CENTRAL SCIENCE (2020)
Network-based drug repurposing for novel coronavirus 2019-nCoV/SARS-CoV-2
Yadi Zhou et al.
CELL DISCOVERY (2020)
Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro
Jia Liu et al.
CELL DISCOVERY (2020)
The COVID-19 vaccine development landscape
Tung Thanh Le et al.
NATURE REVIEWS DRUG DISCOVERY (2020)
Systematic review of the registered clinical trials for coronavirus disease 2019 (COVID-19)
Rui-fang Zhu et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2020)
Building a mechanistic mathematical model of hepatitis C virus entry
Mphatso Kalemera et al.
PLOS COMPUTATIONAL BIOLOGY (2019)
Quantifying Drug Combination Synergy along Potency and Efficacy Axes
Christian T. Meyer et al.
CELL SYSTEMS (2019)
Kinetic model for adherent Vero cell growth and poliovirus production in batch bioreactors
Yang Jiang et al.
PROCESS BIOCHEMISTRY (2019)
You Cannot Have Your Synergy and Efficacy Too
Pramita Sen et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2019)
TMPRSS2 Contributes to Virus Spread and Immunopathology in the Airways of Murine Models after Coronavirus Infection
Naoko Iwata-Yoshikawa et al.
JOURNAL OF VIROLOGY (2019)
Wild-type human coronaviruses prefer cell-surface TMPRSS2 to endosomal cathepsins for cell entry
Kazuya Shirato et al.
VIROLOGY (2018)
Trade-off between synergy and efficacy in combinations of HIV-1 latency-reversing agents
Vipul Gupta et al.
PLOS COMPUTATIONAL BIOLOGY (2018)
Modelling how responsiveness to interferon improves interferon-free treatment of hepatitis C virus infection
Vishnu Venugopal et al.
PLOS COMPUTATIONAL BIOLOGY (2018)
Interferon at the cellular, individual, and population level in hepatitis C virus infection: Its role in the interferon-free treatment era
Rubesh Raja et al.
IMMUNOLOGICAL REVIEWS (2018)
Investigating Different Mechanisms of Action in Combination Therapy for Influenza
Kelli Melville et al.
FRONTIERS IN PHARMACOLOGY (2018)
Cathepsin B and L inhibitors: a patent review (2010-present)
Yu-Yao Li et al.
EXPERT OPINION ON THERAPEUTIC PATENTS (2017)
Inhibitors of hepatitis C virus entry may be potent ingredients of optimal drug combinations
Pranesh Padmanabhan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
The Future of Cysteine Cathepsins in Disease Management
Lovro Kramer et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2017)
Predicting HIV-1 transmission and antibody neutralization efficacy in vivo from stoichiometric parameters
Oliver F. Brandenberg et al.
PLOS PATHOGENS (2017)
SARS and MERS: recent insights into emerging coronaviruses
Emmie de Wit et al.
NATURE REVIEWS MICROBIOLOGY (2016)
Antimicrobial combinations: Bliss independence and Loewe additivity derived from mechanistic multi-hit models
Desiree Y. Baeder et al.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2016)
Protease inhibitors targeting coronavirus and filovirus entry
Yanchen Zhou et al.
ANTIVIRAL RESEARCH (2015)
The HIV-1 Entry Process: A Stoichiometric View
Oliver F. Brandenberg et al.
TRENDS IN MICROBIOLOGY (2015)
Modeling Influenza Virus Infection: A Roadmap for Influenza Research
Alessandro Boianelli et al.
VIRUSES-BASEL (2015)
Mathematical model of adherent Vero cell growth and poliovirus production in animal component free medium
Ramona V. Ursache et al.
BIOPROCESS AND BIOSYSTEMS ENGINEERING (2015)
Synergy of entry inhibitors with direct-acting antivirals uncovers novel combinations for prevention and treatment of hepatitis C
Fei Xiao et al.
GUT (2015)
Analysis of drug combinations: current methodological landscape
Julie Foucquier et al.
PHARMACOLOGY RESEARCH & PERSPECTIVES (2015)
Quantitative Evaluation and Optimization of Co-drugging to Improve Anti-HIV Latency Therapy
Victor C. Wong et al.
CELLULAR AND MOLECULAR BIOENGINEERING (2014)
Emergent properties of the interferon-signalling network may underlie the success of hepatitis C treatment
Pranesh Padmanabhan et al.
NATURE COMMUNICATIONS (2014)
Middle East Respiratory Syndrome Coronavirus Infection Mediated by the Transmembrane Serine Protease TMPRSS2
Kazuya Shirato et al.
JOURNAL OF VIROLOGY (2013)
Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC
V. Stalin Raj et al.
NATURE (2013)
Simultaneous Treatment of Human Bronchial Epithelial Cells with Serine and Cysteine Protease Inhibitors Prevents Severe Acute Respiratory Syndrome Coronavirus Entry
Miyuki Kawase et al.
JOURNAL OF VIROLOGY (2012)
A quantitative basis for antiretroviral therapy for HIV-1 infection
Benjamin L. Jilek et al.
NATURE MEDICINE (2012)
Viral Kinetics Suggests a Reconciliation of the Disparate Observations of the Modulation of Claudin-1 Expression on Cells Exposed to Hepatitis C Virus
Pranesh Padmanabhan et al.
PLOS ONE (2012)
A Transmembrane Serine Protease Is Linked to the Severe Acute Respiratory Syndrome Coronavirus Receptor and Activates Virus Entry
Ana Shulla et al.
JOURNAL OF VIROLOGY (2011)
Evidence that TMPRSS2 Activates the Severe Acute Respiratory Syndrome Coronavirus Spike Protein for Membrane Fusion and Reduces Viral Control by the Humoral Immune Response
Ilona Glowacka et al.
JOURNAL OF VIROLOGY (2011)
Estimating the Threshold Surface Density of Gp120-CCR5 Complexes Necessary for HIV-1 Envelope-Mediated Cell-Cell Fusion
Shiva Naresh Mulampaka et al.
PLOS ONE (2011)
A Critical Subset Model Provides a Conceptual Basis for the High Antiviral Activity of Major HIV Drugs
Lin Shen et al.
SCIENCE TRANSLATIONAL MEDICINE (2011)
Mathematical Model of Viral Kinetics In Vitro Estimates the Number of E2-CD81 Complexes Necessary for Hepatitis C Virus Entry
Pranesh Padmanabhan et al.
PLOS COMPUTATIONAL BIOLOGY (2011)
Efficient Activation of the Severe Acute Respiratory Syndrome Coronavirus Spike Protein by the Transmembrane Protease TMPRSS2
Shutoku Matsuyama et al.
JOURNAL OF VIROLOGY (2010)
Estimating the Stoichiometry of Human Immunodeficiency Virus Entry
Carsten Magnus et al.
JOURNAL OF VIROLOGY (2009)
Modeling amantadine treatment of influenza A virus in vitro
Catherine A. A. Beauchemin et al.
JOURNAL OF THEORETICAL BIOLOGY (2008)
A methodology for performing global uncertainty and sensitivity analysis in systems biology
Simeone Marino et al.
JOURNAL OF THEORETICAL BIOLOGY (2008)
Multi-target therapeutics: when the whole is greater than the sum of the parts
Grant R. Zimmermann et al.
DRUG DISCOVERY TODAY (2007)
Systems biology and combination therapy in the quest for clinical efficacy
Jonathan B. Fitzgerald et al.
NATURE CHEMICAL BIOLOGY (2006)
Stoichiometry of envelope glycoprotein trimers in the entry of human immunodeficiency virus type 1
XZ Yang et al.
JOURNAL OF VIROLOGY (2005)
Inhibitors of cathepsin L prevent severe acute respiratory syndrome coronavirus entry
G Simmons et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Camostat mesilate attenuates pancreatic fibrosis via inhibition of monocytes and pancreatic stellate cells activity
J Gibo et al.
LABORATORY INVESTIGATION (2005)
ACE2: from vasopeptidase to SARS virus receptor
AJ Turner et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2004)
分享论文
