相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Current trends with FOXP3+ regulatory T cell immunotherapy to contest autoimmunity and inflammation
Jamma Trinath et al.
IMMUNOTHERAPY (2019)
Beneficial effects of curtailing immune susceptibility in an Alzheimer's disease model
Giulia Di Benedetto et al.
JOURNAL OF NEUROINFLAMMATION (2019)
Temporal and regional progression of Alzheimer's disease-like pathology in 3xTg-AD mice
Ramona Belfiore et al.
AGING CELL (2019)
2019 Alzheimer's disease facts and figures
Joseph Gaugler et al.
ALZHEIMERS & DEMENTIA (2019)
Sex differences in Alzheimer's disease
Keith R. Laws et al.
CURRENT OPINION IN PSYCHIATRY (2018)
Sex-Dependent Differences in Spontaneous Autoimmunity in Adult 3xTg-AD Mice
Minesh Kapadia et al.
JOURNAL OF ALZHEIMERS DISEASE (2018)
Early Intervention with a Multi-Ingredient Dietary Supplement Improves Mood and Spatial Memory in a Triple Transgenic Mouse Model of Alzheimer's Disease
Craig P. Hutton et al.
JOURNAL OF ALZHEIMERS DISEASE (2018)
Changes in concentrations of tau-reactive antibodies are dependent on sex in Alzheimer's disease patients
Michala Krestova et al.
JOURNAL OF NEUROIMMUNOLOGY (2018)
Sex differences in Alzheimer disease - the gateway to precision medicine
Maria Teresa Ferretti et al.
NATURE REVIEWS NEUROLOGY (2018)
Reversal of memory and neuropsychiatric symptoms and reduced tau pathology by selenium in 3xTg-AD mice
Ann Van der Jeugd et al.
SCIENTIFIC REPORTS (2018)
The antimicrobial protection hypothesis of Alzheimer's disease
Robert D. Moir et al.
ALZHEIMERS & DEMENTIA (2018)
Sustained Immunosuppression Alters Olfactory Function in the MRL Model of CNS Lupus
Minesh Kapadia et al.
JOURNAL OF NEUROIMMUNE PHARMACOLOGY (2017)
A systemic view of Alzheimer disease - insights from amyloid-β metabolism beyond the brain
Jun Wang et al.
NATURE REVIEWS NEUROLOGY (2017)
Effects of sustained i.c.v. infusion of lupus CSF and autoantibodies on behavioral phenotype and neuronal calcium signaling
Minesh Kapadia et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2017)
Prophylactic Active Tau Immunization Leads to Sustained Reduction in Both Tau and Amyloid-β Pathologies in 3xTg Mice
Hameetha Rajamohamedsait et al.
SCIENTIFIC REPORTS (2017)
Maternal dexamethasone exposure ameliorates cognition and tau pathology in the offspring of triple transgenic AD mice
A. Di Meco et al.
MOLECULAR PSYCHIATRY (2016)
The effect of cyclophosphamide on the immune system: implications for clinical cancer therapy
Martina Ahlmann et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2016)
Sex and Genotype Differences in Odor Detection in the 3xTg-AD and 5XFAD Mouse Models of Alzheimer's Disease at 6 Months of Age
Kyle M. Roddick et al.
CHEMICAL SENSES (2016)
Tau downregulates BDNF expression in animal and cellular models of Alzheimer's disease
Elyse Rosa et al.
NEUROBIOLOGY OF AGING (2016)
Aberrant H3.3 dynamics in NAc promote vulnerability to depressive-like behavior
Ashley E. Lepack et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Amyloid-β peptide protects against microbial infection in mouse and worm models of Alzheimer's disease
Deepak Kumar Vijaya Kumar et al.
SCIENCE TRANSLATIONAL MEDICINE (2016)
Age-dependent inverse correlations in CSF and plasma amyloid-β(1-42) concentrations prior to amyloid plaque deposition in the brain of 3xTg-AD mice
Soo Min Cho et al.
SCIENTIFIC REPORTS (2016)
Sex differences in immune responses
Sabra L. Klein et al.
NATURE REVIEWS IMMUNOLOGY (2016)
Gender and incidence of dementia in the Framingham Heart Study from mid-adult life
Genevieve Chene et al.
ALZHEIMERS & DEMENTIA (2015)
Anxiety Symptoms in Amnestic Mild Cognitive Impairment Are Associated with Medial Temporal Atrophy and Predict Conversion to Alzheimer Disease
Linda Mah et al.
AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY (2015)
Cognitive and emotional alterations in young Alzheimer's disease (3xTgAD) mice: Effects of neonatal handling stimulation and sexual dimorphism
T. Canete et al.
BEHAVIOURAL BRAIN RESEARCH (2015)
Reference and working memory deficits in the 3xTg-AD mouse between 2 and 15-months of age: A cross-sectional study
Leanne M. Stevens et al.
BEHAVIOURAL BRAIN RESEARCH (2015)
Early detection of cognitive deficits in the 3xTg-AD mouse model of Alzheimer's disease
Kurt R. Stover et al.
BEHAVIOURAL BRAIN RESEARCH (2015)
Early postnatal handling and environmental enrichment improve the behavioral responses of 17-month-old 3xTg-AD and non-transgenic mice in the Forced Swim Test in a gender-dependent manner
Virginia Torres-Lista et al.
BEHAVIOURAL PROCESSES (2015)
Beyond receptors and signaling: epigenetic factors in the regulation of innate immunity
Stuti Mehta et al.
IMMUNOLOGY AND CELL BIOLOGY (2015)
Brain-derived neurotrophic factor and TrkB expression in the oldest-old, the 90+Study: correlation with cognitive status and levels of soluble amyloid-beta
Bernadeta Michalski et al.
NEUROBIOLOGY OF AGING (2015)
Pyruvate prevents the development of age-dependent cognitive deficits in a mouse model of Alzheimer's disease without reducing amyloid and tau pathology
Elisa Isopi et al.
NEUROBIOLOGY OF DISEASE (2015)
Critical Role of Histone Turnover in Neuronal Transcription and Plasticity
Ian Maze et al.
NEURON (2015)
The problem of genotype and sex differences in life expectancy in transgenic AD mice
Eric A. Rae et al.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2015)
Soluble amyloid-β oligomers as synaptotoxins leading to cognitive impairment in Alzheimer's disease
Sergio T. Ferreira et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2015)
Breaking immune tolerance by targeting Foxp3+ regulatory T cells mitigates Alzheimer's disease pathology
Kuti Baruch et al.
NATURE COMMUNICATIONS (2015)
Behavioral Phenotyping of Murine Disease Models with the Integrated Behavioral Station (INBEST)
Boris Sakic et al.
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2015)
Report of the first international consensus on standardized nomenclature of antinuclear antibody HEp-2 cell patterns 2014-2015
Edward K. L. Chan et al.
FRONTIERS IN IMMUNOLOGY (2015)
α7 Nicotinic Receptor Agonist Enhances Cognition in Aged 3xTg-AD Mice with Robust Plaques and Tangles
Rodrigo Medeiros et al.
AMERICAN JOURNAL OF PATHOLOGY (2014)
Sex Modifies the APOE-Related Risk of Developing Alzheimer Disease
Andre Altmann et al.
ANNALS OF NEUROLOGY (2014)
Cognitive and emotional profiles of aged Alzheimer's disease (3 x TgAD) mice: Effects of environmental enrichment and sexual dimorphism
Gloria Blazquez et al.
BEHAVIOURAL BRAIN RESEARCH (2014)
Apolipoprotein E, gender, and Alzheimer's disease: an overlooked, but potent and promising interaction
Leo Ungar et al.
BRAIN IMAGING AND BEHAVIOR (2014)
Autoimmune Manifestations in the 3xTg-AD Model of Alzheimer's Disease
Monica Marchese et al.
JOURNAL OF ALZHEIMERS DISEASE (2014)
Breaking peripheral immune tolerance to CNS antigens in neurodegenerative diseases: Boosting autoimmunity to fight-off chronic neuroinflammation
Michal Schwartz et al.
JOURNAL OF AUTOIMMUNITY (2014)
Histone H2A.Z subunit exchange controls consolidation of recent and remote memory
Iva B. Zovkic et al.
NATURE (2014)
Specificity of Anti-Tau Antibodies when Analyzing Mice Models of Alzheimer's Disease: Problems and Solutions
Franck R. Petry et al.
PLOS ONE (2014)
Zoopharmacognosy in Diseased Laboratory Mice: Conflicting Evidence
Minesh Kapadia et al.
PLOS ONE (2014)
Genetic mouse models of brain ageing and Alzheimer's disease
Andras Bilkei-Gorzo
PHARMACOLOGY & THERAPEUTICS (2014)
Impairment of nesting behaviour in 3xTg-AD mice
Virginia Torres-Lista et al.
BEHAVIOURAL BRAIN RESEARCH (2013)
CD4 T cells in immunity and immunotherapy of Alzheimer's disease
Alon Monsonego et al.
IMMUNOLOGY (2013)
Characteristics of TBS-Extractable Hyperphosphorylated Tau Species: Aggregation Intermediates in rTg4510 Mouse Brain
Naruhiko Sahara et al.
JOURNAL OF ALZHEIMERS DISEASE (2013)
PAK Inactivation Impairs Social Recognition in 3xTg-AD Mice without Increasing Brain Deposition of Tau and Aβ
Dany Arsenault et al.
JOURNAL OF NEUROSCIENCE (2013)
Early intervention in the 3xTg-AD mice with an amyloid β-antibody fragment ameliorates first hallmarks of alzheimer disease
Lydia Gimenez-Llort et al.
MABS (2013)
TREM2 Variants in Alzheimer's Disease
Rita Guerreiro et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
Sex-Dependent Alterations in Social Behaviour and Cortical Synaptic Activity Coincide at Different Ages in a Model of Alzheimer's Disease
Cyril Bories et al.
PLOS ONE (2012)
Cell Therapy: A Safe and Efficacious Therapeutic Treatment for Alzheimer's Disease in APP+PS1 Mice
Neel R. Nabar et al.
PLOS ONE (2012)
Inflammation Induced by Infection Potentiates Tau Pathological Features in Transgenic Mice
Michael Sy et al.
AMERICAN JOURNAL OF PATHOLOGY (2011)
Alzheimer's disease, autoimmunity and inflammation. The good, the bad and the ugly
F. Sardi et al.
AUTOIMMUNITY REVIEWS (2011)
Physical Exercise Protects Against Alzheimer's Disease in 3xTg-AD Mice
Yoelvis Garcia-Mesa et al.
JOURNAL OF ALZHEIMERS DISEASE (2011)
Effect of Environmental Enrichment on the Immunoendocrine Aging of Male and Female Triple-Transgenic 3xTg-AD Mice for Alzheimer's Disease
Lorena Arranza et al.
JOURNAL OF ALZHEIMERS DISEASE (2011)
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease
Paul Hollingworth et al.
NATURE GENETICS (2011)
Structural brain changes in normal individuals with a maternal history of Alzheimer's
Valentina Berti et al.
NEUROBIOLOGY OF AGING (2011)
Cholinotrophic basal forebrain system alterations in 3xTg-AD transgenic mice
Sylvia E. Perez et al.
NEUROBIOLOGY OF DISEASE (2011)
Progressive regional atrophy in normal adults with a maternal history of Alzheimer disease
Robyn A. Honea et al.
NEUROLOGY (2011)
Chromatin plasticity and the pathogenesis of Huntington disease
Michelle E. Ehrlich et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Transcriptional modulator H2A histone family, member Y (H2AFY) marks Huntington disease activity in man and mouse
Yi Hu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Immunomodulatory effects of cyclophosphamide and implementations for vaccine design
Antonella Sistigu et al.
SEMINARS IN IMMUNOPATHOLOGY (2011)
Brain-derived neurotrophic factor: the link between amyloid-β and memory loss
Margaret Fahnestock
FUTURE NEUROLOGY (2011)
Elevation of β-Amyloid 1-42 Autoantibodies in the Blood of Amnestic Patients With Mild Cognitive Impairment
Daniela Storace et al.
ARCHIVES OF NEUROLOGY (2010)
Intraneuronal β-Amyloid Accumulation in the Amygdala Enhances Fear and Anxiety in Alzheimer's Disease Transgenic Mice
Judit Espana et al.
BIOLOGICAL PSYCHIATRY (2010)
Cyclophosphamide enhances immunity by modulating the balance of dendritic cell subsets in lymphoid organs
Takeshi Nakahara et al.
BLOOD (2010)
Characterization of the 3xTg-AD mouse model of Alzheimer's disease: Part 2. Behavioral and cognitive changes
Roxanne Sterniczuk et al.
BRAIN RESEARCH (2010)
Sex differences in β-amyloid accumulation in 3xTg-AD mice: Role of neonatal sex steroid hormone exposure
Jenna C. Carroll et al.
BRAIN RESEARCH (2010)
High-dose cyclophosphamide for autoimmunity and alloimmunity
Robert A. Brodsky
IMMUNOLOGIC RESEARCH (2010)
Enhanced Selection of High Affinity DNA-Reactive B Cells Following Cyclophosphamide Treatment in Mice
Daisuke Kawabata et al.
PLOS ONE (2010)
Limited Impact of Social Isolation on Alzheimer-Like Symptoms in a Triple Transgenic Mouse Model
Susanna Pietropaolo et al.
BEHAVIORAL NEUROSCIENCE (2009)
Genotoxic Stress Abrogates Renewal of Melanocyte Stem Cells by Triggering Their Differentiation
Ken Inomata et al.
CELL (2009)
Systemic pathology in aged mouse models of Down's syndrome and Alzheimer's disease
Seymour Levine et al.
EXPERIMENTAL AND MOLECULAR PATHOLOGY (2009)
Decreased Brain-Derived Neurotrophic Factor Depends on Amyloid Aggregation State in Transgenic Mouse Models of Alzheimer's Disease
Shiyong Peng et al.
JOURNAL OF NEUROSCIENCE (2009)
Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease
Jean-Charles Lambert et al.
NATURE GENETICS (2009)
Cyclophosphamide and cancer: golden anniversary
Ashkan Emadi et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2009)
Evidence of DNA damage in Alzheimer disease: phosphorylation of histone H2AX in astrocytes
Na-Hye Myung et al.
AGE (2008)
Age-dependent phenotypic characteristics of a triple transgenic mouse model of Alzheimer disease
Susanna Pietropaolo et al.
BEHAVIORAL NEUROSCIENCE (2008)
Females exhibit more extensive amyloid, but not tau, pathology in an Alzheimer transgenic model
Chiho Hirata-Fukae et al.
BRAIN RESEARCH (2008)
Blocking Aβ42 Accumulation Delays the Onset and Progression of Tau Pathology via the C Terminus of Heat Shock Protein70-Interacting Protein: A Mechanistic Link between Aβ and Tau Pathology
Salvatore Oddo et al.
JOURNAL OF NEUROSCIENCE (2008)
Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory
Ganesh M. Shankar et al.
NATURE MEDICINE (2008)
Aβ inhibits the proteasome and enhances amyloid and tau accumulation
Bertrand P. Tseng et al.
NEUROBIOLOGY OF AGING (2008)
Gender-Specific Neuroimmunoendocrine Aging in a Triple-Transgenic 3xTg-AD Mouse Model for Alzheimer's Disease and Its Relation with Longevity
Lydia Gimenez-Llort et al.
NEUROIMMUNOMODULATION (2008)
Age-dependent sexual dimorphism in cognition and stress response in the 3xTg-AD mice
Lani K. Clinton et al.
NEUROBIOLOGY OF DISEASE (2007)
Oligomeric amyloid decreases basal levels of brain-derived neurotrophic factor (BDNF) mRNA via specific downregulation of BDNF transcripts IV and V in differentiated human neuroblastoma cells
Diego J. Garzon et al.
JOURNAL OF NEUROSCIENCE (2007)
Genetic dissection of spontaneous autoimmunity driven by 129-derived chromosome 1 loci when expressed on C57BL/6 mice
Francesco Carlucci et al.
JOURNAL OF IMMUNOLOGY (2007)
Soluble protein oligomers in neurodegeneration:: lessons from the Alzheimer's amyloid β-peptide
Christian Haass et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Modeling behavioral and neuronal symptoms of Alzheimer's disease in mice: A role for intraneuronal amyloid
L. Gimenez-Llort et al.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2007)
Reduction of soluble Aβ and Tau, but not soluble Aβ alone, ameliorates cognitive decline in transgenic mice with plaques and tangles
Salvatore Oddo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Genetic variant BDNF (Val66Met) polymorphism alters anxiety-related behavior
Zhe-Yu Chen et al.
SCIENCE (2006)
Effect of restraint and injection methods on heart rate and body temperature in mice
M. K. Meijer et al.
LABORATORY ANIMALS (2006)
Temporal profile of amyloid-β (Aβ) oligomerization in an in vivo model of Alzheimer disease -: A link between Aβ and tau pathology
S Oddo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Double-negative regulatory T cells - Non-conventional regulators
Christopher W. Thomson et al.
IMMUNOLOGIC RESEARCH (2006)
Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5-mediated pathway in a transgenic model of Alzheimer's disease
M Kitazawa et al.
JOURNAL OF NEUROSCIENCE (2005)
Structure and function of the spleen
RE Mebius et al.
NATURE REVIEWS IMMUNOLOGY (2005)
Precursor form of brain-derived neurotrophic factor and mature brain-derived neurotrophic factor are decreased in the pre-clinical stages of Alzheimer's disease
SY Peng et al.
JOURNAL OF NEUROCHEMISTRY (2005)
Intraneuronal Aβ causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice
LM Billings et al.
NEURON (2005)
Early correlation of microglial activation with enhanced tumor necrosis factor-alpha and monocyte chemoattractant protein-1 expression specifically within the entorhinal cortex of triple transgenic Alzheimer's disease mice
Michelle C. Janelsins et al.
JOURNAL OF NEUROINFLAMMATION (2005)
Spontaneous autoimmunity in 129 and C57BL/6 mice - Implications for autoimmunity described in gene-targeted mice
AE Bygrave et al.
PLOS BIOLOGY (2004)
Autoantibodies to amyloid-β and Alzheimer's disease
BT Hyman et al.
ANNALS OF NEUROLOGY (2001)