期刊
THORACIC CANCER
卷 12, 期 1, 页码 8-12出版社
WILEY
DOI: 10.1111/1759-7714.13746
关键词
Diagnosis; malignant pleural mesothelioma; microRNA; review
资金
- Natural and Science Foundation of Inner Mongolia Autonomous Region for Distinguished Young Scholars [2020JQ07]
Malignant pleural mesothelioma is a highly aggressive cancer with a poor prognosis, emphasizing the importance of timely diagnosis. Laboratory biomarkers offer advantages of reduced invasiveness and cost, making them a promising diagnostic tool. MicroRNA has potential diagnostic value in tissue, circulating, and body fluids.
Malignant pleural mesothelioma (MPM) is a type of cancer originating from the pleura with high aggressiveness and poor prognosis. A timely diagnosis is crucial to improve its prognosis. Laboratory biomarkers have significant advantages of reduced invasiveness, low cost, and are observer-independent, and therefore represent a promising diagnostic tool for MPM. MicroRNA is a family of non-coding RNA that regulates gene expression at the post-transcriptional level. Accumulated studies showed that microRNA, either in tissue, circulating, and body fluid, has potential diagnostic value for various disorders. Here, we reviewed the diagnostic value of microRNA for MPM.
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