相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Structural basis for catalysis and substrate specificity of human ACAT1
Qian Hongwu et al.
NATURE (2020)
Myelin Breakdown in Human Huntington's Disease: Multi-Modal Evidence from Diffusion MRI and Quantitative Magnetization Transfer
Jose Bourbon-Teles et al.
NEUROSCIENCE (2019)
Cerebellar degeneration correlates with motor symptoms in Huntington disease
Malvindar K. Singh-Bains et al.
ANNALS OF NEUROLOGY (2019)
Striatal neurons directly converted from Huntington's disease patient fibroblasts recapitulate age-associated disease phenotypes
Matheus B. Victor et al.
NATURE NEUROSCIENCE (2018)
Early and brain region-specific decrease of de novo cholesterol biosynthesis in Huntington's disease: A cross-validation study in Q175 knock-in mice
Mahalakshmi Shankaran et al.
NEUROBIOLOGY OF DISEASE (2017)
Evidence for altered cholesterol metabolism in Huntington's disease post mortem brain tissue
F. Kreilaus et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2016)
The HTT CAG-Expansion Mutation Determines Age at Death but Not Disease Duration in Huntington Disease
Jae Whan Keum et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2016)
Brain Cholesterol Metabolism and Its Defects: Linkage to Neurodegenerative Diseases and Synaptic Dysfunction
A. M. Petrov et al.
ACTA NATURAE (2016)
The effect of altered sphingolipid acyl chain length on various disease models
Woo-Jae Park et al.
BIOLOGICAL CHEMISTRY (2015)
ACAT1/SOAT1 as a therapeutic target for Alzheimer's disease
Yohei Shibuya et al.
FUTURE MEDICINAL CHEMISTRY (2015)
Human prefrontal cortex phospholipids containing docosahexaenoic acid increase during normal adult aging, whereas those containing arachidonic acid decrease
Sarah E. Norris et al.
NEUROBIOLOGY OF AGING (2015)
HdhQ111 Mice Exhibit Tissue Specific Metabolite Profiles that Include Striatal Lipid Accumulation
Jeffrey B. Carroll et al.
PLOS ONE (2015)
Cholesterol metabolism and homeostasis in the brain
Juan Zhang et al.
PROTEIN & CELL (2015)
Brain Cholesterol Synthesis and Metabolism is Progressively Disturbed in the R6/1 Mouse Model of Huntington's Disease: A Targeted GC-MS/MS Sterol Analysis
Fabian Kreilaus et al.
JOURNAL OF HUNTINGTONS DISEASE (2015)
Huntington disease: natural history, biomarkers and prospects for therapeutics
Christopher A. Ross et al.
NATURE REVIEWS NEUROLOGY (2014)
Huntingtin disrupts lipid bilayers in a polyQ-length dependent manner
Kathleen A. Burke et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2013)
An Improved High-Throughput Lipid Extraction Method for the Analysis of Human Brain Lipids
Sarah K. Abbott et al.
LIPIDS (2013)
Plasma 24S-hydroxycholesterol correlation with markers of Huntington disease progression
Valerio Leoni et al.
NEUROBIOLOGY OF DISEASE (2013)
Chain length-specific properties of ceramides
Sabine Groesch et al.
PROGRESS IN LIPID RESEARCH (2012)
Differential effects of the Huntington's disease CAG mutation in striatum and cerebellum are quantitative not qualitative
Elisa Fossale et al.
HUMAN MOLECULAR GENETICS (2011)
INCREASED EXPRESSION OF ACYL-COENZYME A: CHOLESTEROL ACYLTRANSFERASE-1 AND ELEVATED CHOLESTERYL ESTERS IN THE HIPPOCAMPUS AFTER EXCITOTOXIC INJURY
J. -H. Kim et al.
NEUROSCIENCE (2011)
Elevated Stearoyl-CoA Desaturase in Brains of Patients with Alzheimer's Disease
Giuseppe Astarita et al.
PLOS ONE (2011)
Altered cholesterol and fatty acid metabolism in Huntington disease
Robert C. Block et al.
JOURNAL OF CLINICAL LIPIDOLOGY (2010)
Cerebellar lipid differences between R6/1 transgenic mice and humans with Huntington's disease
Christine A. Denny et al.
JOURNAL OF NEUROCHEMISTRY (2010)
Cholesterol involvement in the pathogenesis of neurodegenerative diseases
Jun-Ping Liu et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2010)
ACAT1 gene ablation increases 24(S)-hydroxycholesterol content in the brain and ameliorates amyloid pathology in mice with AD
Elena Y. Bryleva et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Sterols and sphingolipids: Dynamic duo or partners in crime?
Sonia Gulati et al.
PROGRESS IN LIPID RESEARCH (2010)
Sphingolipid/cholesterol regulation of neurotransmitter receptor conformation and function
Jacques Fantini et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2009)
Lipidomic analyses of the mouse brain after antidepressant treatment: evidence for endogenous release of long-chain fatty acids?
Lynette Hui-Wen Lee et al.
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2009)
Plasma 24S-hydroxycholesterol and caudate MRI in pre-manifest and early Huntingtons disease
Valerio Leoni et al.
BRAIN (2008)
Lipid extraction by methyl-tert-butyl ether for high-throughput lipidomics
Vitali Matyash et al.
JOURNAL OF LIPID RESEARCH (2008)
Low plasma total cholesterol in patients with Huntington's disease and first-degree relatives
Manolis Markianos et al.
MOLECULAR GENETICS AND METABOLISM (2008)
Progressive dysfunction of the cholesterol biosynthesis pathway in the R6/2 mouse model of Huntington's disease
Marta Valenza et al.
NEUROBIOLOGY OF DISEASE (2007)
Change in MRI striatal volumes as a biomarker in preclinical Huntington's disease
Elizabeth H. Aylward
BRAIN RESEARCH BULLETIN (2007)
Cholesterol dysfunction in neurodegenerative diseases: Is Huntington's disease in the list?
Marta Valenza et al.
PROGRESS IN NEUROBIOLOGY (2006)
Antidepressant drugs activate SREBP and up-regulate cholesterol and fatty acid biosynthesis in human glial cells
MB Raeder et al.
NEUROSCIENCE LETTERS (2006)
Dysfunction of the cholesterol biosynthetic pathway in Huntington's disease
M Valenza et al.
JOURNAL OF NEUROSCIENCE (2005)
Antipsychotic drugs activate SREBP-regulated expression of lipid biosynthetic genes in cultured human glioma cells: a novel mechanism of action?
J Ferno et al.
PHARMACOGENOMICS JOURNAL (2005)
Onset and rate of striatal atrophy in preclinical Huntington disease
EH Aylward et al.
NEUROLOGY (2004)
The ACAT inhibitor CP-113,818 markedly reduces amyloid pathology in a mouse model of Alzheimer's disease
B Hutter-Paier et al.
NEURON (2004)
Evidence that accumulation of ceramides and cholesterol esters mediates oxidative stress-induced death of motor neurons in amyotrophic lateral sclerosis
RG Cutler et al.
ANNALS OF NEUROLOGY (2002)