Inhibition and acclimation of nitrifiers exposed to erythromycin

The influence of erythromycin on ammonia -oxidizing bacteria (AOB) and nitrite -oxidizing bacteria (NOB) was investigated using batch and continuous experiments. During the batch experiments, the impact of erythromycin was strictly dose -dependent for AOB and NOB. The continuous addition of 1 mg/L of erythromycin in the long-term exposure experiment made NOB to be sensitive whereas AOB to be minimally sensitive. After a prolonged exposure to concentration, even up to 50 mg/L both NOB and AOB become insensitive to increases in erythromycin. From the seven dosage levels, between 54.3% and 69.1% of erythromycin was removed by adsorption and the percentage of nitrifiers in the microbial community increased from 39.8% to 55.6%. (C) 2016 Elsevier B.V. All rights reserved.