期刊
GASTROENTEROLOGY RESEARCH AND PRACTICE
卷 2021, 期 -, 页码 -出版社
HINDAWI LTD
DOI: 10.1155/2021/6699268
关键词
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资金
- National Natural Science Foundation of China [81700487, 81871905]
- Guangdong Medical Science and Technology Research Fund [A2019243]
- Guangzhou Planned Project of Science and Technology [202002020012, 202002030288, 202002030293]
- Innovative Clinical Technique of Guangzhou [2019GX05]
Gut dysbacteriosis is closely linked to various diseases, and fecal microbiota transplantation is an effective method for reconstructing the gut microbiota. The gut microbiota plays a crucial role in neurological and psychiatric disorders through the microbiota-gut-brain axis, making it a promising new strategy for treating cerebral diseases.
Gut dysbacteriosis is closely related to various intestinal and extraintestinal diseases. Fecal microbiota transplantation (FMT) is a biological therapy that entails transferring the gut microbiota from healthy individuals to patients in order to reconstruct the intestinal microflora in the latter. It has been proved to be an effective treatment for recurrent Clostridium difficile infection. Studies show that the gut microbiota plays an important role in the pathophysiology of neurological and psychiatric disorders through the microbiota-gut-brain axis. Therefore, reconstruction of the healthy gut microbiota is a promising new strategy for treating cerebral diseases. We have reviewed the latest research on the role of gut microbiota in different nervous system diseases as well as FMT in the context of its application in neurological, psychiatric, and other nervous system-related diseases (Parkinson's disease, Alzheimer's disease, multiple sclerosis, epilepsy, autism spectrum disorder, bipolar disorder, hepatic encephalopathy, neuropathic pain, etc.).
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