期刊
BMC NEPHROLOGY
卷 22, 期 1, 页码 -出版社
BMC
DOI: 10.1186/s12882-020-02217-6
关键词
Peritoneal dialysis; Self-management; Malnutrition; Inflammation; Atherosclerosis
资金
- Shanghai Pujiang Program [16PJD032, JYLJ2018011]
The relationship between malnutrition-inflammation-atherosclerosis syndrome (MIAS) and self-management ability in peritoneal dialysis (PD) patients was investigated. Stronger self-management abilities were associated with fewer hospitalizations, higher albumin levels, lower MIS scores, lower IL-6 levels, and fewer MIAS factors.
BackgroundThe relationship between malnutrition-inflammation-atherosclerosis syndrome (MIAS) and self-management ability has not been previously revealed even though both play an important role in the management of peritoneal dialysis (PD) patients.MethodsIn total, 93 patients were enrolled in this study. A self-management questionnaire was used for the evaluation of self-management ability. The identification of MIAS was based on one or more of the following three conditions: C-reactive protein (CRP)>= 10mg/L, malnutrition-inflammation score (MIS)>7, and the presence of atherosclerosis-related medical records. The possible association between different self-management abilities and MIAS was analyzed with a Spearman correlation analysis.ResultsThere were 40 (43.0%) patients in the atherosclerosis group, and 38 (40.9%), 38 (40.9%), 10 (10.8%), and 7 (7.5%) patients in the MIAS0, MIAS1, MIAS2, and MIAS3 groups, respectively. The group with a score above the mean score of the Dialysis Effect Evaluation and Monitoring dimension had a fewer number of hospitalizations, higher albumin levels, lower MIS scores, a lower level of IL-6, and a lower number of MIAS factors. The Pearson and Spearman correlation analyses also revealed that this dimension was negatively correlated with the MIAS, MIS, IL-6, BNP, number of hospitalizations, and age and positively associated with albumin and prealbumin.ConclusionThe Dialysis Effect Evaluation and Monitoring dimension of the self-management scale for PD patients is closely linked to the MIAS, and a better dialysis effect evaluation and monitoring capacity results in a decreased likelihood of exposure to malnutrition and inflammation.Trial registrationChinese Clinical Trial Registry: ChiCTR2000035525 (http://www.chictr.org.cn/showproj.aspx?proj=58110), registered August 13, 2020.
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