期刊
ARTHRITIS CARE & RESEARCH
卷 74, 期 7, 页码 1172-1178出版社
WILEY
DOI: 10.1002/acr.24561
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资金
- NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases [1R03-AR-066840-01A1]
- North Carolina Translational and Clinical Sciences Institute
- National Athletic Trainers Association Research and Education Foundation [14NewInv001]
Changes in T1 rho relaxation times occur within the first 12 months following ACLR in specific regions of the patellofemoral joint on the ACLR and contralateral extremity.
Objective To compare T1 rho relaxation times of the medial and lateral regions of the patella and femoral trochlea at 6 and 12 months following anterior cruciate ligament reconstruction (ACLR) on the ACLR and contralateral extremity. Greater T1 rho relaxation times are associated with a lower proteoglycan density of articular cartilage. Methods This study involved 20 individuals (11 males, 9 females; mean +/- SD age 22 +/- 3.9 years, weight 76.11 +/- 13.48 kg, and height 178.32 +/- 12.32 cm) who underwent a previous unilateral ACLR using a patellar tendon autograft. Magnetic resonance images from both extremities were acquired at 6 and 12 months post-ACLR. Voxel by voxel T1 rho relaxation times were calculated using a 5-image sequence. The medial and lateral regions of the femoral trochlea and patellar articular cartilage were manually segmented on both extremities. Separate extremity (ACLR and contralateral extremity) by time (6 months and 12 months) analysis of variance tests were performed for each region (P < 0.05). Results For the medial patella and lateral trochlea, T1 rho relaxation times increased in both extremities between 6 and 12 months post-ACLR (medial patella P = 0.012; lateral trochlea P = 0.043). For the lateral patella, T1 rho relaxation times were significantly greater on the contralateral extremity compared to the ACLR extremity (P = 0.001). The T1 rho relaxation times of the medial trochlea on the ACLR extremity were significantly greater at 6 (P = 0.005) and 12 months (P < 0.001) compared to the contralateral extremity. T1 rho relaxation times of the medial trochlea significantly increased from 6 to 12 months on the ACLR extremity (P = 0.003). Conclusion Changes in T1 rho relaxation times occur within the first 12 months following ACLR in specific regions of the patellofemoral joint on the ACLR and contralateral extremity.
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