相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Detection of Viral Infections by Innate Immunity
Michael Carty et al.
BIOCHEMICAL PHARMACOLOGY (2021)
Human Endogenous Retroviruses (HERVs): Shaping the Innate Immune Response in Cancers
Vincent Alcazer et al.
CANCERS (2020)
Human TRIM5α senses and restricts LINE-1 elements
Bianca Volkmann et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Human Endogenous Retrovirus K in Cancer: A Potential Biomarker and Immunotherapeutic Target
Gislaine Curty et al.
VIRUSES-BASEL (2020)
Adenosine-to-Inosine RNA Editing of Alu Double-Stranded (ds)RNAs Is Markedly Decreased in Multiple Sclerosis and Unedited Alu dsRNAs Are Potent Activators of Proinflammatory Transcriptional Responses
John T. Tossberg et al.
JOURNAL OF IMMUNOLOGY (2020)
Structural basis for sequestration and autoinhibition of cGAS by chromatin
Sebastian Michalski et al.
NATURE (2020)
Host Gene Regulation by Transposable Elements: The New, the Old and the Ugly
Rocio Enriquez-Gasca et al.
VIRUSES-BASEL (2020)
The Relationship of the Mechanisms of the Pathogenesis of Multiple Sclerosis and the Expression of Endogenous Retroviruses
Vera R. Lezhnyova et al.
BIOLOGY-BASEL (2020)
Nucleocytoplasmic shuttling of SAMHD1 is important for LINE-1 suppression
Juan Du et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2019)
LINE1 Derepression in Aged Wild-Type and SIRT6-Deficient Mice Drives Inflammation
Matthew Simon et al.
CELL METABOLISM (2019)
Intertwined: SAMHD1 cellular functions, restriction, and viral evasion strategies
Catharina Majer et al.
MEDICAL MICROBIOLOGY AND IMMUNOLOGY (2019)
L1 drives IFN in senescent cells and promotes age-associated inflammation
Marco De Cecco et al.
NATURE (2019)
Genome-wide de novo L1 Retrotransposition Connects Endonuclease Activity with Replication
Diane A. Flasch et al.
CELL (2019)
miR-128 Restriction of LINE-1 (L1) Retrotransposition Is Dependent on Targeting hnRNPA1 mRNA
Lianna Fung et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
The Landscape of L1 Retrotransposons in the Human Genome Is Shaped by Pre-insertion Sequence Biases and Post-insertion Selection
Tania Sultana et al.
MOLECULAR CELL (2019)
HERVs, immunity, and autoimmunity: understanding the connection
Matthew Greenig
PEERJ (2019)
IFI16 Targets the Transcription Factor Sp1 to Suppress HIV-1 Transcription and Latency Reactivation
Dominik Hotter et al.
CELL HOST & MICROBE (2019)
The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation
Nathan Kelley et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Restriction of HIV-1 and other retroviruses by TRIM5
Barbie K. Ganser-Pornillos et al.
NATURE REVIEWS MICROBIOLOGY (2019)
Transposable elements in human genetic disease
Lindsay M. Payer et al.
NATURE REVIEWS GENETICS (2019)
Multiple sclerosis - a review
R. Dobson et al.
EUROPEAN JOURNAL OF NEUROLOGY (2019)
Stimulation of Innate Immunity by Host and Viral RNAs
Felix Streicher et al.
TRENDS IN IMMUNOLOGY (2019)
Selective silencing of euchromatic L1s revealed by genome-wide screens for L1 regulators
Nian Liu et al.
NATURE (2018)
cGAS drives noncanonical-inflammasome activation in age-related macular degeneration
Nagaraj Kerur et al.
NATURE MEDICINE (2018)
Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown
Hachung Chung et al.
CELL (2018)
Breaching Self-Tolerance to Alu Duplex RNA Underlies MDA5-Mediated Inflammation
Sadeem Ahmad et al.
CELL (2018)
Post-transcriptional regulation of LINE-1 retrotransposition by AID/APOBEC and ADAR deaminases
Elisa Orecchini et al.
CHROMOSOME RESEARCH (2018)
RNase H2, mutated in Aicardi-Goutieres syndrome, promotes LINE-1 retrotransposition
Maria Benitez-Guijarro et al.
EMBO JOURNAL (2018)
The HUSH complex cooperates with TRIM28 to repress young retrotransposons and new genes
Luisa Robbez-Masson et al.
GENOME RESEARCH (2018)
LINE1 contributes to autoimmunity through both RIG-I- and MDA5-mediated RNA sensing pathways
Ke Zhao et al.
JOURNAL OF AUTOIMMUNITY (2018)
HERVs New Role in Cancer: From Accused Perpetrators to Cheerful Protectors
Norbert Bannert et al.
FRONTIERS IN MICROBIOLOGY (2018)
The SAMHD1-mediated block of LINE-1 retroelements is regulated by phosphorylation
Alexandra Herrmann et al.
MOBILE DNA (2018)
NONO Detects the Nuclear HIV Capsid to Promote cGAS-Mediated Innate Immune Activation
Xavier Lahaye et al.
CELL (2018)
Function of HNRNPC in breast cancer cells by controlling the dsRNA-induced interferon response
Yusheng Wu et al.
EMBO JOURNAL (2018)
Current concepts on Sjogren's syndrome - classification criteria andbiomarkers
Roland Jonsson et al.
EUROPEAN JOURNAL OF ORAL SCIENCES (2018)
Reverse-Transcriptase Inhibitors in the Aicardi-Goutieres Syndrome
Gillian I. Rice et al.
NEW ENGLAND JOURNAL OF MEDICINE (2018)
MicroRNA miR-128 represses LINE-1 (L1) retrotransposition by down-regulating the nuclear import factor TNPO1
Adam Idica et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
Lack of Trex1 Causes Systemic Autoimmunity despite the Presence of Antiretroviral Drugs
Martin Achleitner et al.
JOURNAL OF IMMUNOLOGY (2017)
CG dinucleotide suppression enables antiviral defence targeting non-self RNA
Matthew A. Takata et al.
NATURE (2017)
L1 Mosaicism in Mammals: Extent, Effects, and Evolution
Geoffrey J. Faulkner et al.
TRENDS IN GENETICS (2017)
Co-option of endogenous viral sequences for host cell function
John A. Frank et al.
CURRENT OPINION IN VIROLOGY (2017)
Type I interferon-mediated autoinflammation and autoimmunity
Stefanie Kretschmer et al.
CURRENT OPINION IN IMMUNOLOGY (2017)
Modeling of TREX1-Dependent Autoimmune Disease using Human Stem Cells Highlights L1 Accumulation as a Source of Neuroinflammation
Charles A. Thomas et al.
CELL STEM CELL (2017)
Recognition of Endogenous Nucleic Acids by the Innate Immune System
Axel Roers et al.
IMMUNITY (2016)
Editing of Cellular Self-RNAs by Adenosine Deaminase ADAR1 Suppresses Innate Immune Stress Responses
Cyril X. George et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Discovery of unfixed endogenous retrovirus insertions in diverse human populations
Julia Halo Wildschutte et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
An epigenetic switch ensures transposon repression upon dynamic loss of DNA methylation in embryonic stem cells
Marius Walter et al.
ELIFE (2016)
Roles for retrotransposon insertions in human disease
Dustin C. Hancks et al.
MOBILE DNA (2016)
Expression of Long Interspersed Nuclear Element 1 Retroelements and Induction of Type I Interferon in Patients With Systemic Autoimmune Disease
Clio P. Mavragani et al.
ARTHRITIS & RHEUMATOLOGY (2016)
Upregulated LINE-1 Activity in the Fanconi Anemia Cancer Susceptibility Syndrome Leads to Spontaneous Pro-inflammatory Cytokine Production
Christelle Bregnard et al.
EBIOMEDICINE (2016)
Autoantibodies in SLE: Specificities, Isotypes and Receptors
Barbara Dema et al.
ANTIBODIES (2016)
Characterization of Human Disease Phenotypes Associated with Mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, ADAR, and IFIH1
Yanick J. Crow et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART A (2015)
SnapShot: Fanconi Anemia and Associated Proteins
Anderson T. Wang et al.
CELL (2015)
Primate-Specific ORF0 Contributes to Retrotransposon-Mediated Diversity
Ahmet M. m Denli et al.
CELL (2015)
Fanconi anemia: a model disease for studies on human genetics and advanced therapeutics
Massimo Bogliolo et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2015)
The Ro60 autoantigen binds endogenous retroelements and regulates inflammatory gene expression
T. Hung et al.
SCIENCE (2015)
RNA EDITING RNA editing by ADAR1 prevents MDA5 sensing of endogenous dsRNA as nonself
Brian J. Liddicoat et al.
SCIENCE (2015)
The Zinc-Finger Antiviral Protein ZAP Inhibits LINE and Alu Retrotransposition
John B. Moldovan et al.
PLOS GENETICS (2015)
SAMHD1 Inhibits LINE-1 Retrotransposition by Promoting Stress Granule Formation
Siqi Hu et al.
PLOS GENETICS (2015)
The Broad-Spectrum Antiviral Protein ZAP Restricts Human Retrotransposition
John L. Goodier et al.
PLOS GENETICS (2015)
Genome-wide DNA hypomethylation and RNA:DNA hybrid accumulation in Aicardi-Goutieres syndrome
Yoong Wearn Lim et al.
ELIFE (2015)
IFIH1 Mutation Causes Systemic Lupus Erythematosus With Selective IgA Deficiency
Lien Van Eyck et al.
ARTHRITIS & RHEUMATOLOGY (2015)
Aicardi-Goutieres syndrome and the type I interferonopathies
Yanick J. Crow et al.
NATURE REVIEWS IMMUNOLOGY (2015)
Aicardi-Goutieres Syndrome Is Caused by IFIH1 Mutations
Hirotsugu Oda et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2014)
Premature Activation of the SLX4 Complex by Vpr Promotes G2/M Arrest and Escape from Innate Immune Sensing
Nadine Laguette et al.
CELL (2014)
Antiviral RNA recognition and assembly by RLR family innate immune sensors
Annie M. Bruns et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2014)
Holliday junction resolution: Regulation in space and time
Joao Matos et al.
DNA REPAIR (2014)
An evolutionary arms race between KRAB zinc-finger genes ZNF91/93 and SVA/L1 retrotransposons
Frank M. J. Jacobs et al.
NATURE (2014)
Gain-of-function mutations in IFIH1 cause a spectrum of human disease phenotypes associated with upregulated type I interferon signaling
Gillian I. Rice et al.
NATURE GENETICS (2014)
IFI16 DNA Sensor Is Required for Death of Lymphoid CD4 T Cells Abortively Infected with HIV
Kathryn M. Monroe et al.
SCIENCE (2014)
The RNA-Editing Enzyme ADAR1 Controls Innate Immune Responses to RNA
Niamh M. Mannion et al.
CELL REPORTS (2014)
Human Cytomegalovirus Tegument Protein pUL83 Inhibits IFI16-Mediated DNA Sensing for Immune Evasion
Tuo Li et al.
CELL HOST & MICROBE (2013)
STAU1 binding 3′ UTR IRAlus complements nuclear retention to protect cells from PKR-mediated translational shutdown
Reyad A. Elbarbary et al.
GENES & DEVELOPMENT (2013)
cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING
Andrea Ablasser et al.
NATURE (2013)
Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway
Lijun Sun et al.
SCIENCE (2013)
Cyclic GMP-AMP Synthase Is an Innate Immune Sensor of HIV and Other Retroviruses
Daxing Gao et al.
SCIENCE (2013)
Modulation of LINE-1 and Alu/SVA Retrotransposition by Aicardi-Goutieres Syndrome-Related SAMHD1
Ke Zhao et al.
CELL REPORTS (2013)
Active Transposition in Genomes
Cheng Ran Lisa Huang et al.
ANNUAL REVIEW OF GENETICS, VOL 46 (2012)
DICER1 Loss and Alu RNA Induce Age-Related Macular Degeneration via the NLRP3 Inflammasome and MyD88
Valeria Tarallo et al.
CELL (2012)
Nuclear IFI16 induction of IRF-3 signaling during herpesviral infection and degradation of IFI16 by the viral ICP0 protein
Megan H. Orzalli et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
The KRAB-ZFP/KAP1 System Contributes to the Early Embryonic Establishment of Site-Specific DNA Methylation Patterns Maintained during Development
Simon Quenneville et al.
CELL REPORTS (2012)
MOV10 RNA Helicase Is a Potent Inhibitor of Retrotransposition in Cells
John L. Goodier et al.
PLOS GENETICS (2012)
LINE-1 Elements in Structural Variation and Disease
Christine R. Beck et al.
ANNUAL REVIEW OF GENOMICS AND HUMAN GENETICS, VOL 12 (2011)
IFI16 Acts as a Nuclear Pathogen Sensor to Induce the Inflammasome in Response to Kaposi Sarcoma-Associated Herpesvirus Infection
Nagaraj Kerur et al.
CELL HOST & MICROBE (2011)
Toll-like receptors
Eva Marie Y. Moresco et al.
CURRENT BIOLOGY (2011)
DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration
Hiroki Kaneko et al.
NATURE (2011)
TRIM5 is an innate immune sensor for the retrovirus capsid lattice
Thomas Pertel et al.
NATURE (2011)
An autoimmune disease prevented by anti-retroviral drugs
Gabriele B. Beck-Engeser et al.
RETROVIROLOGY (2011)
The cytosolic exonuclease TREX1 inhibits the innate immune response to human immunodeficiency virus type 1
Nan Yan et al.
NATURE IMMUNOLOGY (2010)
IFI16 is an innate immune sensor for intracellular DNA
Leonie Unterholzner et al.
NATURE IMMUNOLOGY (2010)
Trex1 prevents cell-intrinsic initiation of autoimmunity
Daniel B. Stetson et al.
CELL (2008)
Alu element-mediated gene silencing
Ling-Ling Chen et al.
EMBO JOURNAL (2008)
Mechanism of PKR activation by dsRNA
Peter A. Lemaire et al.
JOURNAL OF MOLECULAR BIOLOGY (2008)
Distinct RIG-I and MDA5 signaling by RNA viruses in innate immunity
Yueh-Ming Loo et al.
JOURNAL OF VIROLOGY (2008)
A unified classification system for eukaryotic transposable elements
Thomas Wicker et al.
NATURE REVIEWS GENETICS (2007)
Mutations in the gene encoding the 3′-5′ DNA exonuclease TREX1 are associated with systemic lupus erythematosus
Min Ae Lee-Kirsch et al.
NATURE GENETICS (2007)
APOBEC3 proteins: major players in intracellular defence against LINE-1-mediated retrotransposition
G. G. Schumann
BIOCHEMICAL SOCIETY TRANSACTIONS (2007)
Heterozygous mutations in TREX1 cause familial chilblain lupus and dominant Aicardi-Goutieres syndrome
Gillian Rice et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2007)
Identification of an infectious progenitor for the multiple-copy HERV-K human endogenous retroelements
Marie Dewannieux et al.
GENOME RESEARCH (2006)
Mutations in the gene encoding the 3′-5′ DNA exonuclease TREX1 cause Aicardi-Goutieres syndrome at the AGS1 locus
Yanick J. Crow et al.
NATURE GENETICS (2006)
Cis-preferential LINE-1 reverse transcriptase activity in ribonucleoprotein particles
Deanna A. Kulpa et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2006)
APOBEC3B and APOBEC3F inhibit L1 retrotransposition by a DNA deamination-independent mechanism
Mark D. Stenglein et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
H Kato et al.
NATURE (2006)
Extensive adenosine-to-inosine editing detected in Alu repeats of antisense RNAs reveals scarcity of sense-antisense duplex formation
Y Kawahara et al.
FEBS LETTERS (2006)
Modulation of microRNA processing and expression through RNA editing by ADAR deaminases
WD Yang et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2006)
Widespread RNA editing of embedded Alu elements in the human transcriptome
DDY Kim et al.
GENOME RESEARCH (2004)
Gene-targeted mice lacking the Trex1 (DNase III) 3′→5′ DNA exonuclease develop inflammatory myocarditis
M Morita et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Widespread A-to-I RNA editing of alu-containing mRNAs in the human transcriptome
A Athanasiadis et al.
PLOS BIOLOGY (2004)
LINE-mediated retrotransposition of marked Alu sequences
M Dewannieux et al.
NATURE GENETICS (2003)
Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein
AM Sheehy et al.
NATURE (2002)
Initial sequencing and analysis of the human genome
ES Lander et al.
NATURE (2001)
Human L1 retrotransposition:: cis preference versus trans complementation
W Wei et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
Requirement of the RNA editing deaminase ADAR1 gene for embryonic erythropoiesis
Q Wang et al.
SCIENCE (2000)
Structure and assembly of the Alu domain of the mammalian signal recognition particle
O Weichenrieder et al.
NATURE (2000)