相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Diversity of small molecule HIV-1 latency reversing agents identified in low- and high-throughput small molecule screens
Pargol Hashemi et al.
MEDICINAL RESEARCH REVIEWS (2020)
CRISPR-engineered T cells in patients with refractory cancer
Edward A. Stadtmauer et al.
SCIENCE (2020)
The forces driving clonal expansion of the HIV-1 latent reservoir
Runxia Liu et al.
VIROLOGY JOURNAL (2020)
Pathways towards human immunodeficiency virus elimination
Prasanta K. Dash et al.
EBIOMEDICINE (2020)
CD32+CD4+ T Cells Are Highly Enriched for HIV DNA and Can Support Transcriptional Latency
Gilles Darcis et al.
CELL REPORTS (2020)
Advances in Long-Acting Agents for the Treatment of HIV Infection
Aadia I. Rana et al.
DRUGS (2020)
Distinct viral reservoirs in individuals with spontaneous control of HIV-1
Chenyang Jiang et al.
NATURE (2020)
The clinical potential of gene editing as a tool to engineer cell-based therapeutics
Candice Ashmore-Harris et al.
CLINICAL AND TRANSLATIONAL MEDICINE (2020)
A quantitative approach for measuring the reservoir of latent HIV-1 proviruses
Katherine M. Bruner et al.
NATURE (2019)
HIV-1 remission following CCR5Δ32/Δ32 haematopoietic stem-cell transplantation
Ravindra K. Gupta et al.
NATURE (2019)
Cat and Mouse: HIV Transcription in Latency, Immune Evasion and Cure/Remission Strategies
Aurelie Delannoy et al.
VIRUSES-BASEL (2019)
Didehydro-Cortistatin A Inhibits HIV-1 by Specifically Binding to the Unstructured Basic Region of Tat
Sonia Mediouni et al.
MBIO (2019)
The Tat inhibitor didehydro-cortistatin A suppresses SIV replication and reactivation
Sonia Mediouni et al.
FASEB JOURNAL (2019)
Telomerase-Targeted Cancer Immunotherapy
Eishiro Mizukoshi et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Augmentation of HIV-specific T cell function by immediate treatment of hyperacute HIV-1 infection
Zaza M. Ndhlovu et al.
SCIENCE TRANSLATIONAL MEDICINE (2019)
Tat inhibition by didehydro-Cortistatin A promotes heterochromatin formation at the HIV-1 long terminal repeat
Chuan Li et al.
EPIGENETICS & CHROMATIN (2019)
HIV shock and kill therapy: In need of revision
Erik Abner et al.
ANTIVIRAL RESEARCH (2019)
Strategies to eradicate HIV from infected patients: elimination of latent provirus reservoirs
Ivan Sadowski et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2019)
Structure-guided drug design identifies a BRD4-selective small molecule that suppresses HIV
Qingli Niu et al.
JOURNAL OF CLINICAL INVESTIGATION (2019)
CRISPR-Edited Stem Cells in a Patient with HIV and Acute Lymphocytic Leukemia
Lei Xu et al.
NEW ENGLAND JOURNAL OF MEDICINE (2019)
Latency reversal agents affect differently the latent reservoir present in distinct CD4+ T subpopulations
Judith Grau-Exposito et al.
PLOS PATHOGENS (2019)
Current Strategies for Elimination of HIV-1 Latent Reservoirs Using Chemical Compounds Targeting Host and Viral Factors
Maxime J. Jean et al.
AIDS RESEARCH AND HUMAN RETROVIRUSES (2019)
Latency-Reversing Agents Induce Differential Responses in Distinct Memory CD4 T Cell Subsets in Individuals on Antiretroviral Therapy
Marion Pardons et al.
CELL REPORTS (2019)
Targeting HIV-1 proviral transcription
Alex Olson et al.
CURRENT OPINION IN VIROLOGY (2019)
Antigen Production After Latency Reversal and Expression of Inhibitory Receptors in CD8+T Cells Limit the Killing of HIV-1 Reactivated Cells
Alba Ruiz et al.
FRONTIERS IN IMMUNOLOGY (2019)
Novel Latency Reversal Agents for HIV-1 Cure
Adam M. Spivak et al.
ANNUAL REVIEW OF MEDICINE, VOL 69 (2018)
Getting the Kill into Shock and Kill: Strategies to Eliminate Latent HIV
Youry Kim et al.
CELL HOST & MICROBE (2018)
The Pathway To Establishing HIV Latency Is Critical to How Latency Is Maintained and Reversed
Simin D. Rezaei et al.
JOURNAL OF VIROLOGY (2018)
HIV integration sites and implications for maintenance of the reservoir
Jori Symons et al.
CURRENT OPINION IN HIV AND AIDS (2018)
Diverse Impacts of HIV Latency-Reversing Agents on CD8+T-Cell Function: Implications for HIV Cure
Genevieve Tyndale Clutton et al.
FRONTIERS IN IMMUNOLOGY (2018)
Barriers for HIV Cure: The Latent Reservoir
Sergio Castro-Gonzalez et al.
AIDS RESEARCH AND HUMAN RETROVIRUSES (2018)
TSC1 and DEPDC5 regulate HIV-1 latency through the mTOR signaling pathway
Shan Jin et al.
EMERGING MICROBES & INFECTIONS (2018)
Shock greets claim of CRISPR-edited babies
Dennis Normile
SCIENCE (2018)
Compounds producing an effective combinatorial regimen for disruption of HIV-1 latency
Pargol Hashemi et al.
EMBO MOLECULAR MEDICINE (2018)
P-TEFb: Finding its ways to release promoter-proximally paused RNA polymerase II
You Li et al.
TRANSCRIPTION-AUSTIN (2018)
Transcriptional Reprogramming during Effector-to-Memory Transition Renders CD4+ T Cells Permissive for Latent HIV-1 Infection
Liang Shan et al.
IMMUNITY (2017)
Interval dosing with the HDAC inhibitor vorinostat effectively reverses HIV latency
Nancie M. Archin et al.
JOURNAL OF CLINICAL INVESTIGATION (2017)
The Short Isoform of BRD4 Promotes HIV-1 Latency by Engaging Repressive SWI/SNF Chromatin-Remodeling Complexes
Ryan J. Conrad et al.
MOLECULAR CELL (2017)
HIV Latency: Should We Shock or Lock?
Gilles Darcis et al.
TRENDS IN IMMUNOLOGY (2017)
In Vivo Suppression of HIV Rebound by Didehydro-Cortistatin A, a Block-and-Lock'' Strategy for HIV-1 Treatment
Cari F. Kessing et al.
CELL REPORTS (2017)
HIV-1 Tat and Viral Latency: What We Can Learn from Naturally Occurring Sequence Variations
Doreen Kamori et al.
FRONTIERS IN MICROBIOLOGY (2017)
Curaxin CBL0100 Blocks HIV-1 Replication and Reactivation through Inhibition of Viral Transcriptional Elongation
Maxime J. Jean et al.
FRONTIERS IN MICROBIOLOGY (2017)
Screening of an FDA-approved compound library identifies levosimendan as a novel anti-HIV-1 agent that inhibits viral transcription
Tsuyoshi Hayashi et al.
ANTIVIRAL RESEARCH (2017)
Reactivation of simian immunodeficiency virus reservoirs in the brain of virally suppressed macaques
Lucio Gama et al.
AIDS (2017)
Sequential treatment with 5-aza-2-deoxycytidine and deacetylase inhibitors reactivates HIV-1
Sophie Bouchat et al.
EMBO MOLECULAR MEDICINE (2016)
Functional screening of guide RNAs targeting the regulatory and structural HIV-1 viral genome for a cure of AIDS
Chaoran Yin et al.
AIDS (2016)
Progress Toward HIV Eradication: Case Reports, Current Efforts, and the Challenges Associated with Cure
Alyssa R. Martin et al.
ANNUAL REVIEW OF MEDICINE, VOL 67 (2016)
Expression of HIV-encoded microRNA-TAR and its inhibitory effect on viral replication in human primary macrophages
Li Li et al.
ARCHIVES OF VIROLOGY (2016)
A telomerase-derived peptide regulates reactive oxygen species and hepatitis C virus RNA replication in HCV-infected cells via heat shock protein 90
Seoung-Ae Lee et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2016)
The mTOR Complex Controls HIV Latency
Emilie Besnard et al.
CELL HOST & MICROBE (2016)
Monocyte exosomes induce adhesion molecules and cytokines via activation of NF-B in endothelial cells
Norina Tang et al.
FASEB JOURNAL (2016)
Excision of HIV-1 DNA by gene editing: a proof-of-concept in vivo study
R. Kaminski et al.
GENE THERAPY (2016)
HIV-1 drug resistance and resistance testing
Dana S. Clutter et al.
INFECTION GENETICS AND EVOLUTION (2016)
Inhibition of Heat Shock Protein 90 Prevents HIV Rebound
Pheroze Joshi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Measuring the latent reservoir in vivo
Marta Massanella et al.
JOURNAL OF CLINICAL INVESTIGATION (2016)
The Latent Reservoir for HIV-1: How Immunologic Memory and Clonal Expansion Contribute to HIV-1 Persistence
Alexandra J. Murray et al.
JOURNAL OF IMMUNOLOGY (2016)
Specific Inhibition of HIV Infection by the Action of Spironolactone in T Cells
Benoit Lacombe et al.
JOURNAL OF VIROLOGY (2016)
Reversal of Latency as Part of a Cure for HIV-1
Thomas Aagaard Rasmussen et al.
TRENDS IN MICROBIOLOGY (2016)
HIV-1 Eracication: Early Trials (and Tribulations)
Adam M. Spivak et al.
TRENDS IN MOLECULAR MEDICINE (2016)
Residual inflammation and viral reservoirs: alliance against an HIV cure
Marta Massanella et al.
CURRENT OPINION IN HIV AND AIDS (2016)
CRISPR/Cas9-Derived Mutations Both Inhibit HIV-1 Replication and Accelerate Viral Escape
Zhen Wang et al.
CELL REPORTS (2016)
Current status and prospects of HIV treatment
Tomas Cihlar et al.
CURRENT OPINION IN VIROLOGY (2016)
Inflammatory Markers Associated With Subclinical Coronary Artery Disease: The Multicenter AIDS Cohort Study
Hossein Bahrami et al.
JOURNAL OF THE AMERICAN HEART ASSOCIATION (2016)
Post-Treatment Controllers: Role in HIV Cure Research
Leslie R. Cockerham et al.
CURRENT HIV/AIDS REPORTS (2016)
CRISPR/Cas9 genome editing - new and old ethical issues arising from a revolutionary technology
Martina Baumann
NANOETHICS (2016)
Combined eff ect of Vacc-4x, recombinant human granulocyte macrophage colony-stimulating factor vaccination, and romidepsin on the HIV-1 reservoir (REDUC): a single-arm, phase 1B/2A trial
Steffen Leth et al.
LANCET HIV (2016)
Elimination of HIV-1 Genomes from Human T-lymphoid Cells by CRISPR/Cas9 Gene Editing
Rafal Kaminski et al.
SCIENTIFIC REPORTS (2016)
Inhibition of HIV-1 reactivation by a telomerase-derived peptide in a HSP90-dependent manner
Hong Kim et al.
SCIENTIFIC REPORTS (2016)
Targeting NF-κB Signaling with Protein Kinase C Agonists As an Emerging Strategy for Combating HIV Latency
Guochun Jiang et al.
AIDS RESEARCH AND HUMAN RETROVIRUSES (2015)
Understanding HIV Latency: The Road to an HIV Cure
Matthew S. Dahabieh et al.
ANNUAL REVIEW OF MEDICINE, VOL 66 (2015)
Ex Vivo Bioactivity and HIV-1 Latency Reversal by Ingenol Dibenzoate and Panobinostat in Resting CD4+ T Cells from Aviremic Patients
Adam M. Spivak et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2015)
HIV-1 functional cure: will the dream come true?
Chao Liu et al.
BMC MEDICINE (2015)
A Hardwired HIV Latency Program
Brandon S. Razooky et al.
CELL (2015)
An Evolutionary Role for HIV Latency in Enhancing Viral Transmission
Igor M. Rouzine et al.
CELL (2015)
Cell-Specific RNA Aptamer against Human CCR5 Specifically Targets HIV-1 Susceptible Cells and Inhibits HIV-1 Infectivity
Jiehua Zhou et al.
CHEMISTRY & BIOLOGY (2015)
Didehydro-Cortistatin A Inhibits HIV-1 Tat Mediated Neuroinflammation and Prevents Potentiation of Cocaine Reward in Tat Transgenic Mice
Sonia Mediouni et al.
CURRENT HIV RESEARCH (2015)
No time to waste-the ethical challenges created by CRISPR CRISPR/Cas, being an efficient, simple, and cheap technology to edit the genome of any organism, raises many ethical and regulatory issues beyond the use to manipulate human germ line cells
Arthur L. Caplan et al.
EMBO REPORTS (2015)
FACT Proteins, SUPT16H and SSRP1, Are Transcriptional Suppressors of HIV-1 and HTLV-1 That Facilitate Viral Latency
Huachao Huang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Ex vivo analysis identifies effective HIV-1 latency-reversing drug combinations
Gregory M. Laird et al.
JOURNAL OF CLINICAL INVESTIGATION (2015)
Regulation of HIV-1 Latency by Chromatin Structure and Nuclear Architecture
Marina Lusic et al.
JOURNAL OF MOLECULAR BIOLOGY (2015)
Targeting of mTOR catalytic site inhibits multiple steps of the HIV-1 lifecycle and suppresses HIV-1 viremia in humanized mice
Alonso Heredia et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
The Tat Inhibitor Didehydro-Cortistatin A Prevents HIV-1 Reactivation from Latency
Guillaume Mousseau et al.
MBIO (2015)
How does the timing of antiretroviral therapy initiation in acute infection affect HIV reservoirs?
Jintanat Ananworanich et al.
CURRENT OPINION IN HIV AND AIDS (2015)
Synergistic Reactivation of Latent HIV Expression by Ingenol-3-Angelate, PEP005, Targeted NF-kB Signaling in Combination with JQ1 Induced p-TEFb Activation
Guochun Jiang et al.
PLOS PATHOGENS (2015)
The Depsipeptide Romidepsin Reverses HIV-1 Latency In Vivo
Ole S. Sogaard et al.
PLOS PATHOGENS (2015)
High-affinity RNA Aptamers Against the HIV-1 Protease Inhibit Both In Vitro Protease Activity and Late Events of Viral Replication
Sonald Duclair et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2015)
A Small Molecule Screen Identifies an Inhibitor of DNA Repair Inducing the Degradation of TFIIH and the Chemosensitization of Tumor Cells to Platinum
Sergey Alekseev et al.
CHEMISTRY & BIOLOGY (2014)
Unfixed Endogenous Retroviral Insertions in the Human Population
Emanuele Marchi et al.
JOURNAL OF VIROLOGY (2014)
New ex vivo approaches distinguish effective and ineffective single agents for reversing HIV-1 latency in vivo
C. Korin Bullen et al.
NATURE MEDICINE (2014)
Shift of HIV Tropism in Stem-Cell Transplantation with CCR5 Delta32 Mutation
Lambros Kordelas et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)
High Interest in a Long-Acting Injectable Formulation of Pre-Exposure Prophylaxis for HIV in Young Men Who Have Sex with Men in NYC: A P18 Cohort Substudy
Kathrine Meyers et al.
PLOS ONE (2014)
Heat shock protein 90 controls HIV-1 reactivation from latency
Ian Anderson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Triptolide inhibits human immunodeficiency virus type 1 replication by promoting proteasomal degradation of Tat protein
Zhitao Wan et al.
RETROVIROLOGY (2014)
8.2% of the Human Genome Is Constrained: Variation in Rates of Turnover across Functional Element Classes in the Human Lineage
Chris M. Rands et al.
PLOS GENETICS (2014)
Activation of HIV Transcription with Short-Course Vorinostat in HIV-Infected Patients on Suppressive Antiretroviral Therapy
Julian H. Elliott et al.
PLOS PATHOGENS (2014)
Practical Considerations in Gene Therapy for HIV Cure
Rodica Stan et al.
CURRENT HIV/AIDS REPORTS (2014)
Panobinostat, a histone deacetylase inhibitor, for latent-virus reactivation in HIV-infected patients on suppressive antiretroviral therapy: a phase 1/2, single group, clinical trial
Thomas A. Rasmussen et al.
LANCET HIV (2014)
Replication-Competent Noninduced Proviruses in the Latent Reservoir Increase Barrier to HIV-1 Cure
Ya-Chi Ho et al.
CELL (2013)
Immune activation and HIV persistence: implications for curative approaches to HIV infection
Nichole R. Klatt et al.
IMMUNOLOGICAL REVIEWS (2013)
High Levels of CD2 Expression Identify HIV-1 Latently Infected Resting Memory CD4+ T Cells in Virally Suppressed Subjects
Maria Iglesias-Ussel et al.
JOURNAL OF VIROLOGY (2013)
HIV-1 transcription and latency: an update
Carine Van Lint et al.
RETROVIROLOGY (2013)
Multiplex Genome Engineering Using CRISPR/Cas Systems
Le Cong et al.
SCIENCE (2013)
Harnessing the CRISPR/Cas9 system to disrupt latent HIV-1 provirus
Hirotaka Ebina et al.
SCIENTIFIC REPORTS (2013)
Comparative Analysis of Measures of Viral Reservoirs in HIV-1 Eradication Studies
Susanne Eriksson et al.
PLOS PATHOGENS (2013)
Aptamer-Based Therapeutics: New Approaches to Combat Human Viral Diseases
Ka-To Shum et al.
PHARMACEUTICALS (2013)
An Analog of the Natural Steroidal Alkaloid Cortistatin A Potently Suppresses Tat-Dependent HIV Transcription
Guillaume Mousseau et al.
CELL HOST & MICROBE (2012)
Dynamic roles for NF-κB in HTLV-I and HIV-1 retroviral pathogenesis
Jonathan K. Chan et al.
IMMUNOLOGICAL REVIEWS (2012)
Biomarkers of Microbial Translocation and Macrophage Activation: Association With Progression of Subclinical Atherosclerosis in HIV-1 Infection
Theodoros Kelesidis et al.
JOURNAL OF INFECTIOUS DISEASES (2012)
Regulation of Cyclin T1 and HIV-1 Replication by MicroRNAs in Resting CD4+ T Lymphocytes
Karen Chiang et al.
JOURNAL OF VIROLOGY (2012)
Long-Term Nonprogressor and Elite Controller Patients Who Control Viremia Have a Higher Percentage of Methylation in Their HIV-1 Proviral Promoters than Aviremic Patients Receiving Highly Active Antiretroviral Therapy
Juan Antonio Palacios et al.
JOURNAL OF VIROLOGY (2012)
Paucity of HIV DNA Methylation in Latently Infected, Resting CD4+ T Cells from Infected Individuals Receiving Antiretroviral Therapy
Jana Blazkova et al.
JOURNAL OF VIROLOGY (2012)
Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy
N. M. Archin et al.
NATURE (2012)
Plasma HIV Viral Rebound following Protocol-Indicated Cessation of ART Commenced in Primary and Chronic HIV Infection
Elizabeth Hamlyn et al.
PLOS ONE (2012)
Engineering HIV-1-Resistant T-Cells from Short-Hairpin RNA-Expressing Hematopoietic Stem/Progenitor Cells in Humanized BLT Mice
Gene-Errol E. Ringpis et al.
PLOS ONE (2012)
Regulation and function of mTOR signalling in T cell fate decisions
Hongbo Chi
NATURE REVIEWS IMMUNOLOGY (2012)
Impaired Infectivity of Ritonavir-resistant HIV Is Rescued by Heat Shock Protein 90AB1
Pheroze Joshi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
XPB, a subunit of TFIIH, is a target of the natural product triptolide
Denis V. Titov et al.
NATURE CHEMICAL BIOLOGY (2011)
In vivo, in vitro, and in silico analysis of methylation of the HIV-1 provirus
Leonard Chavez et al.
METHODS (2011)
Triptolide (TPL) Inhibits Global Transcription by Inducing Proteasome-Dependent Degradation of RNA Polymerase II (Pol II)
Ying Wang et al.
PLOS ONE (2011)
A Chinese herb Tripterygium wilfordii Hook F in the treatment of rheumatoid arthritis: mechanism, efficacy, and safety
Jun Bao et al.
RHEUMATOLOGY INTERNATIONAL (2011)
Curaxins: Anticancer Compounds that Simultaneously Suppress NF-κB and Activate p53 by Targeting FACT
Alexander V. Gasparian et al.
SCIENCE TRANSLATIONAL MEDICINE (2011)
Epidemiology and clinical characteristics of elite controllers
Jason F. Okulicz et al.
CURRENT OPINION IN HIV AND AIDS (2011)
Repressive LTR Nucleosome Positioning by the BAF Complex Is Required for HIV Latency
Haleh Rafati et al.
PLOS BIOLOGY (2011)
Dissecting the role of mTOR: Lessons from mTOR inhibitors
Ryan J. O. Dowling et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2010)
Key factors in mTOR regulation
Xiaochun Bai et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2010)
Involvement of Histone H3 Lysine 9 (H3K9) Methyltransferase G9a in the Maintenance of HIV-1 Latency and Its Reactivation by BIX01294
Kenichi Imai et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
P-TEFb Kinase Complex Phosphorylates Histone H1 to Regulate Expression of Cellular and HIV-1 Genes
Siobhan K. O'Brien et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Gyrase B Inhibitor Impairs HIV-1 Replication by Targeting Hsp90 and the Capsid Protein
Luciano Vozzolo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Chromatin remodelling during development
Lena Ho et al.
NATURE (2010)
Transcription through the HIV-1 nucleosomes: Effects of the PBAF complex in Tat activated transcription
Rebecca Easley et al.
VIROLOGY (2010)
Modeling HIV persistence, the latent reservoir, and viral blips
Libin Rong et al.
JOURNAL OF THEORETICAL BIOLOGY (2009)
Bromodomain Protein Brd4 Regulates Human Immunodeficiency Virus Transcription through Phosphorylation of CDK9 at Threonine 29
Meisheng Zhou et al.
JOURNAL OF VIROLOGY (2009)
HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation
Nicolas Chomont et al.
NATURE MEDICINE (2009)
Long-Term Control of HIV by CCR5 Delta32/Delta32 Stem-Cell Transplantaion
Gero Huetter et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
miR-198 Inhibits HIV-1 Gene Expression and Replication in Monocytes and Its Mechanism of Action Appears To Involve Repression of Cyclin T1
Tzu-Ling Sung et al.
PLOS PATHOGENS (2009)
CpG Methylation Controls Reactivation of HIV from Latency
Jana Blazkova et al.
PLOS PATHOGENS (2009)
Novel dual inhibitory function aptamer-siRNA delivery system for HIV-1 therapy
Jiehua Zhou et al.
MOLECULAR THERAPY (2008)
CBF-1 promotes transcriptional silencing during the establishment of HIV-1 latency
Mudit Tyagi et al.
EMBO JOURNAL (2007)
Optimal design and validation of antiviral siRNA for targeting HIV-I
Yuki Naito et al.
RETROVIROLOGY (2007)
Cellular microRNAs contribute to HIV-1 latency in resting primary CD4+ T lymphocytes
Jialing Huang et al.
NATURE MEDICINE (2007)
Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription
Dwayne A. Bisgrovet et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
RNAi therapeutics: Principles, prospects and challenges
Lars Aagaard et al.
ADVANCED DRUG DELIVERY REVIEWS (2007)
Suv39H1 and HP1γ are responsible for chromatin-mediated HIV-1 transcriptional silencing and post-integration latency
Isaure du Chene et al.
EMBO JOURNAL (2007)
A review of levosimendan in the treatment of heart failure
Hulya Akhan Kasikcioglu et al.
VASCULAR HEALTH AND RISK MANAGEMENT (2006)
Inhibition of human immunodeficiency virus type 1 by RNA interference using long-hairpin RNA
P. Konstantinova et al.
GENE THERAPY (2006)
Requirement for SWI/SNF chromatin-remodeling complex in Tat-mediated activation of the HIV-1 promoter
Celine Treand et al.
EMBO JOURNAL (2006)
Inhibitors of HIV-1 Tat-mediated transactivation
SN Richter et al.
CURRENT MEDICINAL CHEMISTRY (2006)
HIV-1 inactivation by nucleic acid aptamers
DM Held et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2006)
Tat gets the green light on transcription initiation
J Brady et al.
RETROVIROLOGY (2005)
The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription
MK Jang et al.
MOLECULAR CELL (2005)
Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein brd4
ZY Yang et al.
MOLECULAR CELL (2005)
HIV-1 TAR RNA: The target of molecular interactions between the virus and its host
S Bannwarth et al.
CURRENT HIV RESEARCH (2005)
HIV-1 can escape from RNA interference by evolving an alternative structure in its RNA genome
EM Westerhout et al.
NUCLEIC ACIDS RESEARCH (2005)
Human immunodeficiency virus type 1 escapes from RNA interference-mediated inhibition
AT Das et al.
JOURNAL OF VIROLOGY (2004)
Antisense-mediated inhibition of human immunodeficiency virus (HIV) replication by use of an HIV type 1-based vector results in severely attenuated mutants incapable of developing resistance
XB Lu et al.
JOURNAL OF VIROLOGY (2004)
Rapamycin causes down-regulation of CCR5 and accumulation of anti-HIV β-chemokines:: An approach to suppress R5 strains of HIV-1
A Heredia et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Human immunodeficiency virus-1 Tat protein and methamphetamine interact synergistically to impair striatal dopaminergic function
WF Maragos et al.
JOURNAL OF NEUROCHEMISTRY (2002)
Potent and specific inhibition of human immunodeficiency virus type 1 replication by RNA interference
GA Coburn et al.
JOURNAL OF VIROLOGY (2002)
HIV-1 integration in the human genome favors active genes and local hotspots
ARW Schröder et al.
CELL (2002)
Modulation of HIV-1 replication by RNA interference
JM Jacque et al.
NATURE (2002)
siRNA-directed inhibition of HIV-1 infection
CD Novina et al.
NATURE MEDICINE (2002)
Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells
NS Lee et al.
NATURE BIOTECHNOLOGY (2002)
Counterregulation of chromatin deacetylation and histone deacetylase occupancy at the integrated promoter of human immunodeficiency virus type 1 (HIV-1) by the HIV-1 repressor YY1 and HIV-1 activator Tat
GC He et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
NF-κB binds P-TEFb to stimulate transcriptional elongation by RNA polymerase II
M Barboric et al.
MOLECULAR CELL (2001)
DSIF and NELF interact with RNA polymerase II elongation complex and HIV-1 Tat stimulates P-TEFb-mediated phosphorylation of RNA polymerase II and DSIF during transcription elongation
YH Ping et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Acetylation of HIV-1 Tat by CBP/P300 increases transcription of integrated HIV-1 genome and enhances binding to core histones
LW Deng et al.
VIROLOGY (2000)
The human factors YY1 and LSF repress the human immunodeficiency virus type 1 long terminal repeat via recruitment of histone deacetylase 1
JJ Coull et al.
JOURNAL OF VIROLOGY (2000)
P-TEFb, a cyclin-dependent kinase controlling elongation by RNA polymerase II
DH Price
MOLECULAR AND CELLULAR BIOLOGY (2000)