Composite engineered biomaterial adaptable for repair and regeneration of wounds

Ongoing investigations in wound repair bring new opportunities and challenges for creating novel composite engineered biomaterials. Efforts have been directed toward using different combinations of biomaterials with the goal of providing an ideal biomimetic substitute for native tissue. A universal formula using collagen, fibroin and a synthetic polymer is proposed. By modifying the ratio of the building blocks, the composite material can be fabricated to match the mechanical property of different types of tissues and be further tuned to carry desirable physical and biological function. The results should provide composite engineered materials comparable to native tissue in order to repair and regenerate a variety of wounds and tissues.

Automated summary

Ongoing investigations in wound repair are focused on creating novel composite engineered biomaterials by using different combinations of biomaterials to mimic native tissue. A universal formula using collagen, fibroin and a synthetic polymer has been proposed to fabricate composite materials matching the mechanical properties of different tissues. The goal is to provide composite engineered materials comparable to native tissue for repairing and regenerating various wounds and tissues.