4.5 Article

Impact of early vs. delayed initiation of dutasteride/tamsulosin combination therapy on the risk of acute urinary retention or BPH-related surgery in LUTS/BPH patients with moderate-to-severe symptoms at risk of disease progression

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Summary: By analyzing pooled data, it was found that the use of dutasteride and tamsulosin-dutasteride combination therapy significantly reduced the baseline risk of acute urinary retention or BPH-related surgery. The study also highlighted the contribution of different baseline characteristics to the risk of these events, and emphasized that tamsulosin monotherapy has no impact on long-term risk for individuals.

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