相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Synthesis, Structure-Activity Relationship, and Mechanistic Studies of Aminoquinazolinones Displaying Antimycobacterial Activity
Jessica N. Akester et al.
ACS INFECTIOUS DISEASES (2020)
Cytotoxicity and Antimycobacterial Properties of Pyrrolo[1,2-a]quinoline Derivatives: Molecular Target Identification and Molecular Docking Studies
Katharigatta N. Venugopala et al.
ANTIBIOTICS-BASEL (2020)
The Global Fight Against Tuberculosis
Charles L. Daley
THORACIC SURGERY CLINICS (2019)
Identifying Regimens Containing TBI-166, a New Drug Candidate against Mycobacterium tuberculosis In Vitro and In Vivo
Ye Zhang et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2019)
First-Time-in-Human Study and Prediction of Early Bactericidal Activity for GSK3036656, a Potent Leucyl-tRNA Synthetase Inhibitor for Tuberculosis Treatment
David Tenero et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2019)
Synthesis and Structure-Activity relationship of 1-(5-isoquinolinesulfonyl)piperazine analogues as inhibitors of Mycobacterium tuberculosis IMPDH
Vinayak Singh et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2019)
Treatment of Drug - Resistant Tuberculosis
Sundari R. Mase et al.
CLINICS IN CHEST MEDICINE (2019)
Drug-resistance in Mycobacterium tuberculosis: where we stand
Amanda Mabhula et al.
MEDCHEMCOMM (2019)
In vitro and in vivo activity of contezolid (MRX-I) against Mycobacterium tuberculosis
Carolyn Shoen et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2018)
Clofazimine: A useful antibiotic for drug-resistant tuberculosis
Reza Mirnejad et al.
BIOMEDICINE & PHARMACOTHERAPY (2018)
Delpazolid Oxazolidinone antibiotic Treatment of tuberculosis
G. Kaul et al.
DRUGS OF THE FUTURE (2018)
Evolution of drug resistance in Mycobacterium tuberculosis: a review on the molecular determinants of resistance and implications for personalized care
Navisha Dookie et al.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2018)
Acquisition of Delamanid Under a Compassionate Use Program for Extensively Drug-Resistant Tuberculosis - United States, 2017
Alfred A. Lardizabal et al.
MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT (2018)
Isoniazid derivatives and their anti-tubercular activity
Yuan-Qiang Hu et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2017)
Effectiveness and safety of standardised shorter regimens for multidrug-resistant tuberculosis: individual patient data and aggregate data meta-analyses
Faiz Ahmad Khan et al.
EUROPEAN RESPIRATORY JOURNAL (2017)
Discovery of a Potent and Specific M-tuberculosis Leucyl-tRNA Synthetase Inhibitor: (S)-3-(Aminomethyl)-4-chloro-7-(2hydroxyethoxy)benzo[c][1,2]oxaborol-1(3H)-ol (GSK656)
Xianfeng Li et al.
JOURNAL OF MEDICINAL CHEMISTRY (2017)
High-dose rifampicin, moxifloxacin, and SQ109 for treating tuberculosis: a multi-arm, multi-stage randomised controlled trial
Martin J. Boeree et al.
LANCET INFECTIOUS DISEASES (2017)
An optimized background regimen design to evaluate the contribution of levofloxacin to multidrug-resistant tuberculosis treatment regimens: study protocol for a randomized controlled trial
Tara C. Bouton et al.
TRIALS (2017)
Diagnosis and Treatment of Drug-Resistant Tuberculosis
Jose A. Caminero et al.
ARCHIVOS DE BRONCONEUMOLOGIA (2017)
Outcomes, infectiousness, and transmission dynamics of patients with extensively drug-resistant tuberculosis and home-discharged patients with programmatically incurable tuberculosis: a prospective cohort study
Keertan Dheda et al.
LANCET RESPIRATORY MEDICINE (2017)
Bedaquiline and Delamanid Combination Treatment of 5 Patients with Pulmonary Extensively Drug-Resistant Tuberculosis
Andrey Maryandyshev et al.
EMERGING INFECTIOUS DISEASES (2017)
Population Pharmacokinetics of AZD-5847 in Adults with Pulmonary Tuberculosis
Abdullah Alsultan et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2017)
Identification and validation of novel drug targets in Mycobacterium tuberculosis
Vinayak Singh et al.
DRUG DISCOVERY TODAY (2017)
In Vivo Dearomatization of the Potent Antituberculosis Agent BTZ043 via Meisenheimer Complex Formation
Florian Kloss et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)
New agents for the treatment of drug-resistant Mycobacterium tuberculosis
Daniel T. Hoagland et al.
ADVANCED DRUG DELIVERY REVIEWS (2016)
Early Bactericidal Activity of AZD5847 in Patients with Pulmonary Tuberculosis
Jennifer J. Furin et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2016)
Characterization of DprE1-Mediated Benzothiazinone Resistance in Mycobacterium tuberculosis
Caroline Shi-Yan Foo et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2016)
Bedaquiline and multidrug-resistant tuberculosis: a systematic and critical analysis of the evidence
Emanuele Pontali et al.
EUROPEAN RESPIRATORY JOURNAL (2016)
First case of extensively drug-resistant tuberculosis treated with both delamanid and bedaquiline
Marina Tadolini et al.
EUROPEAN RESPIRATORY JOURNAL (2016)
To be or not to be exclusive: the sutezolid story Response
Christy Wyskiel
LANCET GLOBAL HEALTH (2016)
Early phase evaluation of SQ109 alone and in combination with rifampicin in pulmonary TB patients
Norbert Heinrich et al.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2015)
Bactericidal Activity and Mechanism of Action of AZD5847, a Novel Oxazolidinone for Treatment of Tuberculosis
V. Balasubramanian et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2014)
Lead Optimization of a Novel Series of Imidazo[1,2-a]pyridine Amides Leading to a Clinical Candidate (Q203) as a Multi- and Extensively-Drug-Resistant Anti-tuberculosis Agent
Sunhee Kang et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
New Potent Antibacterial Oxazolidinone (MRX-I) with an Improved Class Safety Profile
Mikhail F. Gordeev et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
Lead Optimization of 1,4-Azaindoles as Antimycobacterial Agents
Pravin S. Shirude et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
Multitarget Drug Discovery for Tuberculosis and Other Infectious Diseases
Kai Li et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
The ongoing challenge of latent tuberculosis
H. Esmail et al.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2014)
Linezolid for the treatment of drug-resistant tuberculosis in children: A review and recommendations
Anthony J. Garcia-Prats et al.
TUBERCULOSIS (2014)
Efficacy of Nitazoxanide against Clinical Isolates of Mycobacterium tuberculosis
Kristina Shigyo et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2013)
Azaindoles: Noncovalent DprE1 Inhibitors from Scaffold Morphing Efforts, Kill Mycobacterium tuberculosis and Are Efficacious in Vivo
Pravin S. Shirude et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
Discovery of Q203, a potent clinical candidate for the treatment of tuberculosis
Kevin Pethe et al.
NATURE MEDICINE (2013)
Advances in the development of new tuberculosis drugs and treatment regimens
Alimuddin Zumla et al.
NATURE REVIEWS DRUG DISCOVERY (2013)
INFECTIOUS DISEASE Approval of Novel TB Drug Celebrated-With Restraint
Jon Cohen
SCIENCE (2013)
A Review of the Evidence for Using Bedaquiline (TMC207) to Treat Multi-Drug Resistant Tuberculosis
Gregory J. Fox et al.
INFECTIOUS DISEASES AND THERAPY (2013)
SQ109 Targets MmpL3, a Membrane Transporter of Trehalose Monomycolate Involved in Mycolic Acid Donation to the Cell Wall Core of Mycobacterium tuberculosis
Kapil Tahlan et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2012)
Substrate specificity of the deazaflavin-dependent nitroreductase from Mycobacterium tuberculosis responsible for the bioreductive activation of bicyclic nitroimidazoles
Meera Gurumurthy et al.
FEBS JOURNAL (2012)
Discovery and development of SQ109: a new antitubercular drug with a novel mechanism of action
Katherine A. Sacksteder et al.
FUTURE MICROBIOLOGY (2012)
Linezolid-containing regimens for the treatment of drug-resistant tuberculosis in South African children
P. C. Rose et al.
INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE (2012)
Identification of Less Lipophilic Riminophenazine Derivatives for the Treatment of Drug-Resistant Tuberculosis
Dongfeng Zhang et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Global tuberculosis control: lessons learnt and future prospects
Christian Lienhardt et al.
NATURE REVIEWS MICROBIOLOGY (2012)
Linezolid for Treatment of Chronic Extensively Drug-Resistant Tuberculosis
Myungsun Lee et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
Biomarker-Assisted Dose Selection for Safety and Efficacy in Early Development of PNU-100480 for Tuberculosis
Robert S. Wallis et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2011)
Identification of SQ609 as a lead compound from a library of dipiperidines
Elena Bogatcheva et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2011)
Nitroimidazoles for the treatment of TB: past, present and future
Tathagata Mukherjee et al.
FUTURE MEDICINAL CHEMISTRY (2011)
The challenge of new drug discovery for tuberculosis
Anil Koul et al.
NATURE (2011)
Clinical Isolates of Mycobacterium tuberculosis in Four European Hospitals Are Uniformly Susceptible to Benzothiazinones
Maria Rosalia Pasca et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2010)
In Vitro Interactions between New Antitubercular Drug Candidates SQ109 and TMC207
Venkata M. Reddy et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2010)
Linezolid use for treatment of multidrug-resistant and extensively drug-resistant tuberculosis, New York City, 2000-06
Holly A. Anger et al.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2010)
Hepatotoxic effects of therapies for tuberculosis
Bahaa E. Senousy et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2010)
Promising Antituberculosis Activity of the Oxazolidinone PNU-100480 Relative to That of Linezolid in a Murine Model
K. N. Williams et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2009)
Tuberculosis into the 2010s: Is the Glass Half Full?
Anna P. Ralph et al.
CLINICAL INFECTIOUS DISEASES (2009)
Benzothiazinones Kill Mycobacterium tuberculosis by Blocking Arabinan Synthesis
Vadim Makarov et al.
SCIENCE (2009)
Impact of the interaction of R207910 with rifampin on the treatment of tuberculosis studied in the mouse model
Nacer Lounis et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2008)
Powerful bactericidal and sterilizing activity of a regimen containing PA-824, moxifloxacin, and pyrazinamide in a murine model of tuberculosis
Eric Nuermberger et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2008)
The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning
Daniel N. Wilson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
PA-824 Kills Nonreplicating Mycobacterium tuberculosis by Intracellular NO Release
Ramandeep Singh et al.
SCIENCE (2008)
Mechanism-based pharmacokinetic-pharmacodynamic modeling of antimicrobial drug effects
David Czock et al.
JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS (2007)
Bactericidal activity of OPC-67683 against drug-tolerant Mycobacterium tuberculosis
Oluwabunmi Y. Saliu et al.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2007)
In vitro antimycobacterial spectrum of a diarylquinoline ATP synthase inhibitor
Emma Huitric et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2007)
Diarylquinolines target subunit c of mycobacterial ATP synthase
Anil Koul et al.
NATURE CHEMICAL BIOLOGY (2007)
Old and new drugs for the treatment of tuberculosis in children
Peter R. Donald et al.
PAEDIATRIC RESPIRATORY REVIEWS (2007)
Synthesis and antituberculosis activity of a novel series of optically active 6-nitro-2,3-dihydroimidazo[2,1-b]oxazoles
Hirofumi Sasaki et al.
JOURNAL OF MEDICINAL CHEMISTRY (2006)
OPC-67683, a nitro-dihydro-imidazooxazole derivative with promising action against tuberculosis in vitro and in mice
Makoto Matsumoto et al.
PLOS MEDICINE (2006)
Combinations of R207910 with drugs used to treat multidrug-resistant tuberculosis have the potential to shorten treatment duration
Nacer Lounis et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2006)
Decaprenylphosphoryl arabinofuranose, the donor of the D-arabinofuranosyl residues of mycobacterial arabinan, is formed via a two-step epimerization of decaprenylphosphoryl ribose
K Mikusová et al.
JOURNAL OF BACTERIOLOGY (2005)
Identification of a new antitubercular drug candidate, SQ109, from a combinatorial library of 1,2-ethylenediamines
M Protopopova et al.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2005)
Linezolid for the treatment of multidrug-resistant tuberculosis
J Fortún et al.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2005)
A diarylquinoline drug active on the ATP synthase of Mycobacterium tuberculosis
K Andries et al.
SCIENCE (2005)
Oxazolidinones: activity, mode of action, and mechanism of resistance
B Bozdogan et al.
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2004)
Linezolid: The first oxazolidinone antimicrobial - In response
RC Moellering
ANNALS OF INTERNAL MEDICINE (2003)
Combinatorial lead optimization of [1,2]-diamines based on ethambutol as potential antituberculosis preclinical candidates
RE Lee et al.
JOURNAL OF COMBINATORIAL CHEMISTRY (2003)
Use of transposon Tn5367 mutagenesis and a nitroimidazopyran-based selection system to demonstrate a requirement for fbiA and fbiB in coenzyme F420 biosynthesis by Mycobacterium bovis BCG
KP Choi et al.
JOURNAL OF BACTERIOLOGY (2001)
A small-molecule nitroimidazopyran drug candidate for the treatment of tuberculosis
CK Stover et al.
NATURE (2000)