Chromatin, DNA Replication, and Transcription: Closing the Triangle

Chromatin features are correctly transferred to the daughter strands during genome replication. Recent discoveries demonstrate that replicative DNA polymerases interact physically with histone dimers and tetramers, facilitating histone transfer at the DNA replication fork. This role may explain the transcriptional phenotypic defects of Arabidopsis mutants in genes encoding DNA polymerase subunits.

Automated summary

Recent discoveries show that replicative DNA polymerases interact with histone dimers and tetramers, facilitating the transfer of chromatin features during DNA replication. This interaction may explain the transcriptional phenotypic defects observed in Arabidopsis mutants with mutations in genes encoding DNA polymerase subunits.