The coupling reaction of α-silylamines with Baylis-Hillman adducts by visible light photoredox catalysis

The preparation of N-containing alpha,beta-unsaturated carboxylate derivatives from alpha-silylamine and Baylis-Hillman adducts under visible light irradiation was reported. The formation of alpha-aminoalkyl radical is regioselective compared with the previous reports. The reaction was successfully performed without additional additives under mild conditions. (C) 2020 Elsevier Ltd. All rights reserved.

Automated summary

The preparation of N-containing alpha,beta-unsaturated carboxylate derivatives from alpha-silylamine and Baylis-Hillman adducts under visible light irradiation was reported. The formation of alpha-aminoalkyl radical is regioselective compared with the previous reports. The reaction was successfully performed without additional additives under mild conditions.