Photo-induced radical borylation of hemiacetals via C-C bond cleavage

In this study, we reported a photo-induced radical borylation of hemiacetal derivatives via C-C bond cleavage. This transformation can be realized under mild conditions with simple reaction settings and irradiation of visible light. A series of substrates, including both cyclic and linear hemiacetal derivatives, were effectively transformed to the borylation product in moderate to good yields. Finally, the mechanism was studied in detail by DFT calculations, suggesting insight of the radical borylation process. (C) 2020 Elsevier Ltd. All rights reserved.

Automated summary

In this study, a photo-induced radical borylation of hemiacetal derivatives via C-C bond cleavage was reported. The transformation can be achieved under mild conditions with simple reaction settings and irradiation of visible light. Detailed mechanism studies through DFT calculations provided insights into the radical borylation process.