Homogeneous Catalyzed Aryl-Aryl Cross-Couplings in Flow

Aryl-aryl cross-coupling reactions are important reactions for the production of various biaryl compounds. This short review covers the various aryl-aryl cross-coupling reactions carried out in flow, focusing on the metal species of the aryl nucleophiles used in the cross-coupling reactions. 1 Introduction 2 Suzuki-Miyaura Coupling (B) 3 Migita-Kosugi-Stille Coupling (Sn) 4 Negishi Coupling (Zn) 5 Kumada-Tamao-Corriu Coupling (Mg) 6 Murahashi Coupling (Li) 7 Conclusion

Automated summary

This short review covers various aryl-aryl cross-coupling reactions carried out in flow, focusing on the metal species of the aryl nucleophiles used.