期刊
SYNTHESIS-STUTTGART
卷 53, 期 10, 页码 1833-1841出版社
GEORG THIEME VERLAG KG
DOI: 10.1055/a-1337-4684
关键词
Lewis base; catalysis; Michael addition; alpha-amino nitriles; gamma-amino acid derivatives
资金
- National Natural Science Foundation of China [21772063]
A novel protocol for the synthesis of functionalized gamma-amino acid esters and gamma-lactams through a controllable Lewis base catalyzed Michael addition of alpha-aminonitriles to simple activated alkenes has been developed, demonstrating the scope, versatility, and efficiency of the process.
A novel protocol for the synthesis of functionalized gamma-amino acid esters and gamma-lactams through a controllable Lewis base catalyzed Michael addition of alpha-aminonitriles to simple activated alkenes has been developed. The scope, versatility, and efficiency of the process were demonstrated.
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