相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Promising New Inhibitors of Tyrosyl-DNA Phosphodiesterase I (Tdp 1) Combining 4-Arylcoumarin and Monoterpenoid Moieties as Components of Complex Antitumor Therapy
Tatyana M. Khomenko et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Apical sodium-dependent bile acid transporter, drug target for bile acid related diseases and delivery target for prodrugs: Current and future challenges
Ming Li et al.
PHARMACOLOGY & THERAPEUTICS (2020)
Design, Synthesis, and Biological Investigation of Novel Classes of 3-Carene-Derived Potent Inhibitors of TDP1
Irina Il'ina et al.
MOLECULES (2020)
Updates in bile acid-bioactive molecule conjugates and their applications
Roli Mishra et al.
STEROIDS (2020)
Secondary Bile Acids and Short Chain Fatty Acids in the Colon: A Focus on Colonic Microbiome, Cell Proliferation, Inflammation, and Cancer
Huawei Zeng et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Identification of a ligand binding hot spot and structural motifs replicating aspects of tyrosyl-DNA phosphodiesterase I (TDP1) phosphoryl recognition by crystallographic fragment cocktail screening
George T. Lountos et al.
NUCLEIC ACIDS RESEARCH (2019)
Semisynthetic bile acids: a new therapeutic option for metabolic syndrome
Slavica Lazarevic et al.
PHARMACOLOGICAL RESEARCH (2019)
New Hydrazinothiazole Derivatives of Usnic Acid as Potent Tdp1 Inhibitors
Aleksander S. Filimonov et al.
MOLECULES (2019)
Irinotecan: 25 years of cancer treatment
Christian Bailly
PHARMACOLOGICAL RESEARCH (2019)
Novel tyrosyl-DNA phosphodiesterase 1 inhibitors enhance the therapeutic impact of topotecan on in vivo tumor models
A. L. Zakharenko et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2019)
The Development of a Weighted Index to Optimise Compound Libraries for High Throughput Screening
Chatchakorn Eurtivong et al.
MOLECULAR INFORMATICS (2019)
Bile acid receptors in the biliary tree: TGR5 in physiology and disease
Kathleen Deutschmann et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2018)
Novel Semisynthetic Derivatives of Bile Acids as Effective Tyrosyl-DNA Phosphodiesterase 1 Inhibitors
Oksana V. Salomatina et al.
MOLECULES (2018)
Synthesis and antimalarial activity of 3′-trifluoromethylated 1,2,4-trioxolanes and 1,2,4,5-tetraoxane based on deoxycholic acid
Emil Yu. Yamansarov et al.
STEROIDS (2018)
Bile Acids Activated Receptors Regulate innate immunity
Stefano Fiorucci et al.
FRONTIERS IN IMMUNOLOGY (2018)
Synthesis and Biological Evaluation of the First Triple Inhibitors of Human Topoisomerase 1, Tyrosyl-DNA Phosphodiesterase 1 (Tdp1), and Tyrosyl-DNA Phosphodiesterase 2 (Tdp2)
Ping Wang et al.
JOURNAL OF MEDICINAL CHEMISTRY (2017)
Rational Design of Nucleoside-Bile Acid Conjugates Incorporating a Triazole Moiety for Anticancer Evaluation and SAR Exploration
Maria Luisa Navacchia et al.
MOLECULES (2017)
Modern approaches to modification of bile acids for the synthesis of compounds possessing valuable physicochemical and biological properties
Irina I. Poopadyuk et al.
RUSSIAN CHEMICAL REVIEWS (2017)
Current status of poly(ADP-ribose) polymerase inhibitors and future directions
Akihiro Ohmoto et al.
ONCOTARGETS AND THERAPY (2017)
Bile acid transporter mediated endocytosis of oral bile acid conjugated nanocomplex
Jooho Park et al.
BIOMATERIALS (2017)
Defining Known Drug Space Using DFT
Anna M. Matuszek et al.
MOLECULAR INFORMATICS (2016)
Bilosomes in the context of oral immunization: development, challenges and opportunities
Anshuman Shukla et al.
DRUG DISCOVERY TODAY (2016)
Bile acids and bile acid derivatives: use in drug delivery systems and as therapeutic agents
Celia Faustino et al.
EXPERT OPINION ON DRUG DELIVERY (2016)
Pharmacology of bile acid receptors: Evolution of bile acids from simple detergents to complex signaling molecules
Bryan L. Copple et al.
PHARMACOLOGICAL RESEARCH (2016)
Deoxycholic acid derivatives as inhibitors of P-glycoprotein-mediated multidrug efflux
Luc Rocheblave et al.
STEROIDS (2016)
Design and strategies for bile acid mediated therapy and imaging
Md Nurunnabi et al.
RSC ADVANCES (2016)
Synthesis and biological evaluation of novel tyrosyl-DNA phosphodiesterase 1 inhibitors with a benzopentathiepine moiety
Alexandra Zakharenko et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2015)
Bile acid nuclear receptor FXR and digestive system diseases
Lili Ding et al.
ACTA PHARMACEUTICA SINICA B (2015)
Bile acid receptors as targets for drug development
Frank G. Schaap et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2014)
Application of bile acids in drug formulation and delivery
Maja Stojancevic et al.
FRONTIERS IN LIFE SCIENCE (2013)
Glycochenodeoxycholate induces rat alveolar epithelial type II cell death and inhibits surfactant secretion in vitro
Hu Zhangxue et al.
FREE RADICAL BIOLOGY AND MEDICINE (2012)
Analysis of the Active-Site Mechanism of Tyrosyl-DNA Phosphodiesterase I: A Member of the Phospholipase D Superfamily
Stefan Gajewski et al.
JOURNAL OF MOLECULAR BIOLOGY (2012)
Wine Compounds as a Source for HTS Screening Collections. A Feasibility Study
Feng Zhu et al.
MOLECULAR INFORMATICS (2012)
Transporters, Trojan horses and therapeutics: suitability of bile acid and peptide transporters for drug delivery
Werner Kramer
BIOLOGICAL CHEMISTRY (2011)
AP-site cleavage activity of tyrosyl-DNA phosphodiesterase 1
Natalia A. Lebedeva et al.
FEBS LETTERS (2011)
Tyrosyl-DNA Phosphodiesterase 1 Targeting for Modulation of Camptothecin-Based Treatment
G. L. Beretta et al.
CURRENT MEDICINAL CHEMISTRY (2010)
Synergistic decrease of DNA single-strand break repair rates in mouse neural cells lacking both Tdp1 and aprataxin
Sherif F. El-Khamisy et al.
DNA REPAIR (2009)
Empirical Scoring Functions for Advanced Protein-Ligand Docking with PLANTS
Oliver Korb et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2009)
4-Pregnen-21-ol-3,20-dione-21-(4-bromobenzenesulfonate) (NSC 88915) and Related Novel Steroid Derivatives as Tyrosyl-DNA Phosphodiesterase (Tdp1) Inhibitors
Thomas S. Dexheimer et al.
JOURNAL OF MEDICINAL CHEMISTRY (2009)
Tyrosyl-DNA phosphodiesterase as a target for anticancer therapy
Thomas S. Dexheimer et al.
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY (2008)
Bile acids: Chemistry, pathochemistry, biology, pathobiology, and therapeutics
A. F. Hofmann et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2008)
Benchmarking the reliability of QikProp. Correlation between experimental and predicted values
Leukothea Ioakimidis et al.
QSAR & COMBINATORIAL SCIENCE (2008)
Combination therapy of heparin-deoxycholic acid conjugate and doxorubicin against squamous cell carcinoma and B16F10 melanoma
Kyeongsoon Park et al.
PHARMACEUTICAL RESEARCH (2008)
Novel high-throughput electrochemiluminescent assay for identification of human tyrosyl-DNA phosphodiesterase (Tdp1) inhibitors and characterization of furamidine (NSC 305831) as an inhibitor of Tdp1
Smitha Antony et al.
NUCLEIC ACIDS RESEARCH (2007)
Heparin-deoxycholic acid chemical conjugate as an anticancer drug carrier and its antitumor activity
Kyeongsoon Park et al.
JOURNAL OF CONTROLLED RELEASE (2006)
Oral delivery of chemical conjugates of heparin and deoxycholic acid in aqueous formulation
SK Kim et al.
THROMBOSIS RESEARCH (2006)
General and targeted statistical potentials for protein-ligand interactions
WTM Mooij et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2005)
SCAN1 mutant Tdp1 accumulates the enzyme-DNA intermediate and causes camptothecin hypersensitivity
H Interthal et al.
EMBO JOURNAL (2005)
Engineered resistance to camptothecin and antifolates by retroviral coexpression of tyrosyl DNA phosphodiesterase-I and thymidylate synthase
MC Nivens et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2004)
TDP1 overexpression in human cells counteracts DNA damage mediated by topoisomerases I and II
HU Barthelmes et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Announcing the worldwide Protein Data Bank
H Berman et al.
NATURE STRUCTURAL BIOLOGY (2003)
Improved protein-ligand docking using GOLD
ML Verdonk et al.
PROTEINS-STRUCTURE FUNCTION AND GENETICS (2003)
A G protein-coupled receptor responsive to bile acids
Y Kawamata et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
The tyrosyl-DNA phosphodiesterase Tdp1 is a member of the phospholipase D superfamily
H Interthal et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
The Protein Data Bank
HM Berman et al.
NUCLEIC ACIDS RESEARCH (2000)
分享论文
