4.2 Article

Deoxycholic acid as a molecular scaffold for tyrosyl-DNA phosphodiesterase 1 inhibition: A synthesis, structure-activity relationship and molecular modeling study

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

Updates in bile acid-bioactive molecule conjugates and their applications

Roli Mishra et al.

STEROIDS (2020)

Review Biochemistry & Molecular Biology

Secondary Bile Acids and Short Chain Fatty Acids in the Colon: A Focus on Colonic Microbiome, Cell Proliferation, Inflammation, and Cancer

Huawei Zeng et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Review Pharmacology & Pharmacy

Semisynthetic bile acids: a new therapeutic option for metabolic syndrome

Slavica Lazarevic et al.

PHARMACOLOGICAL RESEARCH (2019)

Article Biochemistry & Molecular Biology

New Hydrazinothiazole Derivatives of Usnic Acid as Potent Tdp1 Inhibitors

Aleksander S. Filimonov et al.

MOLECULES (2019)

Review Pharmacology & Pharmacy

Irinotecan: 25 years of cancer treatment

Christian Bailly

PHARMACOLOGICAL RESEARCH (2019)

Article Chemistry, Medicinal

Novel tyrosyl-DNA phosphodiesterase 1 inhibitors enhance the therapeutic impact of topotecan on in vivo tumor models

A. L. Zakharenko et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2019)

Article Chemistry, Medicinal

The Development of a Weighted Index to Optimise Compound Libraries for High Throughput Screening

Chatchakorn Eurtivong et al.

MOLECULAR INFORMATICS (2019)

Review Biochemistry & Molecular Biology

Bile acid receptors in the biliary tree: TGR5 in physiology and disease

Kathleen Deutschmann et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2018)

Article Biochemistry & Molecular Biology

Novel Semisynthetic Derivatives of Bile Acids as Effective Tyrosyl-DNA Phosphodiesterase 1 Inhibitors

Oksana V. Salomatina et al.

MOLECULES (2018)

Review Immunology

Bile Acids Activated Receptors Regulate innate immunity

Stefano Fiorucci et al.

FRONTIERS IN IMMUNOLOGY (2018)

Review Biotechnology & Applied Microbiology

Current status of poly(ADP-ribose) polymerase inhibitors and future directions

Akihiro Ohmoto et al.

ONCOTARGETS AND THERAPY (2017)

Article Engineering, Biomedical

Bile acid transporter mediated endocytosis of oral bile acid conjugated nanocomplex

Jooho Park et al.

BIOMATERIALS (2017)

Article Chemistry, Medicinal

Defining Known Drug Space Using DFT

Anna M. Matuszek et al.

MOLECULAR INFORMATICS (2016)

Review Pharmacology & Pharmacy

Bilosomes in the context of oral immunization: development, challenges and opportunities

Anshuman Shukla et al.

DRUG DISCOVERY TODAY (2016)

Review Pharmacology & Pharmacy

Bile acids and bile acid derivatives: use in drug delivery systems and as therapeutic agents

Celia Faustino et al.

EXPERT OPINION ON DRUG DELIVERY (2016)

Article Biochemistry & Molecular Biology

Deoxycholic acid derivatives as inhibitors of P-glycoprotein-mediated multidrug efflux

Luc Rocheblave et al.

STEROIDS (2016)

Review Chemistry, Multidisciplinary

Design and strategies for bile acid mediated therapy and imaging

Md Nurunnabi et al.

RSC ADVANCES (2016)

Article Biochemistry & Molecular Biology

Synthesis and biological evaluation of novel tyrosyl-DNA phosphodiesterase 1 inhibitors with a benzopentathiepine moiety

Alexandra Zakharenko et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2015)

Review Pharmacology & Pharmacy

Bile acid nuclear receptor FXR and digestive system diseases

Lili Ding et al.

ACTA PHARMACEUTICA SINICA B (2015)

Review Gastroenterology & Hepatology

Bile acid receptors as targets for drug development

Frank G. Schaap et al.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2014)

Article Multidisciplinary Sciences

Application of bile acids in drug formulation and delivery

Maja Stojancevic et al.

FRONTIERS IN LIFE SCIENCE (2013)

Article Biochemistry & Molecular Biology

Glycochenodeoxycholate induces rat alveolar epithelial type II cell death and inhibits surfactant secretion in vitro

Hu Zhangxue et al.

FREE RADICAL BIOLOGY AND MEDICINE (2012)

Article Biochemistry & Molecular Biology

Analysis of the Active-Site Mechanism of Tyrosyl-DNA Phosphodiesterase I: A Member of the Phospholipase D Superfamily

Stefan Gajewski et al.

JOURNAL OF MOLECULAR BIOLOGY (2012)

Article Chemistry, Medicinal

Wine Compounds as a Source for HTS Screening Collections. A Feasibility Study

Feng Zhu et al.

MOLECULAR INFORMATICS (2012)

Article Biochemistry & Molecular Biology

AP-site cleavage activity of tyrosyl-DNA phosphodiesterase 1

Natalia A. Lebedeva et al.

FEBS LETTERS (2011)

Review Biochemistry & Molecular Biology

Tyrosyl-DNA Phosphodiesterase 1 Targeting for Modulation of Camptothecin-Based Treatment

G. L. Beretta et al.

CURRENT MEDICINAL CHEMISTRY (2010)

Article Chemistry, Medicinal

Empirical Scoring Functions for Advanced Protein-Ligand Docking with PLANTS

Oliver Korb et al.

JOURNAL OF CHEMICAL INFORMATION AND MODELING (2009)

Article Oncology

Tyrosyl-DNA phosphodiesterase as a target for anticancer therapy

Thomas S. Dexheimer et al.

ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY (2008)

Review Biochemistry & Molecular Biology

Bile acids: Chemistry, pathochemistry, biology, pathobiology, and therapeutics

A. F. Hofmann et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2008)

Article Chemistry, Medicinal

Benchmarking the reliability of QikProp. Correlation between experimental and predicted values

Leukothea Ioakimidis et al.

QSAR & COMBINATORIAL SCIENCE (2008)

Article Chemistry, Multidisciplinary

Heparin-deoxycholic acid chemical conjugate as an anticancer drug carrier and its antitumor activity

Kyeongsoon Park et al.

JOURNAL OF CONTROLLED RELEASE (2006)

Article Biochemistry & Molecular Biology

General and targeted statistical potentials for protein-ligand interactions

WTM Mooij et al.

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2005)

Article Biochemistry & Molecular Biology

SCAN1 mutant Tdp1 accumulates the enzyme-DNA intermediate and causes camptothecin hypersensitivity

H Interthal et al.

EMBO JOURNAL (2005)

Article Biochemistry & Molecular Biology

TDP1 overexpression in human cells counteracts DNA damage mediated by topoisomerases I and II

HU Barthelmes et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Letter Biochemistry & Molecular Biology

Announcing the worldwide Protein Data Bank

H Berman et al.

NATURE STRUCTURAL BIOLOGY (2003)

Article Biochemistry & Molecular Biology

Improved protein-ligand docking using GOLD

ML Verdonk et al.

PROTEINS-STRUCTURE FUNCTION AND GENETICS (2003)

Article Biochemistry & Molecular Biology

A G protein-coupled receptor responsive to bile acids

Y Kawamata et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Multidisciplinary Sciences

The tyrosyl-DNA phosphodiesterase Tdp1 is a member of the phospholipase D superfamily

H Interthal et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)

Article Biochemistry & Molecular Biology

The Protein Data Bank

HM Berman et al.

NUCLEIC ACIDS RESEARCH (2000)