期刊
E-POLYMERS
卷 16, 期 5, 页码 351-358出版社
WALTER DE GRUYTER GMBH
DOI: 10.1515/epoly-2016-0138
关键词
biocompatibility; electrospinning; freeze-drying; morphology; polymer membranes
资金
- Faculty of Materials Science and Ceramics, AGH University of Science and Technology, Krakow, Poland [11.11.160.616]
The aim of this work was to develop bioresorbable, asymmetric membranes for guided bone regeneration (GBR). Two resorbable polymers - polylactide (PLA) and polycaprolactone (PCL) were used in fabrication process. Two different manufacturing methods were applied: electrospinning in the case of PLA and freeze-drying of PCL. Mechanical properties, stability in a water environment and biocompatibility of fabricated membranes were evaluated. Microstructure [scanning electron microscopy (SEM)] of the membranes was assessed in terms of level of porosity, as well as size and shape of the pores. Study showed that combination of electrospinning and freeze-drying methods allows biocompatible PLA/PCL bi-phasic materials of appropriate mechanical properties and diverse microstructure to be produced, that should on the one hand prevent soft tissue growth, and on the other hand be a suitable scaffold for the growth of bone cells.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据