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The Hedgehog Pathway Promotes Blood-Brain Barrier Integrity and CNS Immune Quiescence
Jorge Ivan Alvarez et al.
SCIENCE (2011)
Synaptic Pruning by Microglia Is Necessary for Normal Brain Development
Rosa C. Paolicelli et al.
SCIENCE (2011)
Association of visual function and ganglion cell layer thickness in patients with diabetes mellitus type 1 and no or minimal diabetic retinopathy
Hille W. van Dijk et al.
VISION RESEARCH (2011)
Evaluation of Retinal Function and Flicker Light-Induced Retinal Vascular Response in Normotensive Patients with Diabetes without Retinopathy
Amelie Lecleire-Collet et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2011)
Multifocal Electroretinograms Predict Onset of Diabetic Retinopathy in Adult Patients with Diabetes
Wendy W. Harrison et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2011)
Visual Dysfunction Associated with Diabetic Retinopathy
Gregory R. Jackson et al.
CURRENT DIABETES REPORTS (2010)
TNF-α Signals Through PKCζ/NF-κB to Alter the Tight Junction Complex and Increase Retinal Endothelial Cell Permeability
Celia A. Aveleira et al.
DIABETES (2010)
Muller Cell-Derived VEGF Is Essential for Diabetes-Induced Retinal Inflammation and Vascular Leakage
Juanjuan Wang et al.
DIABETES (2010)
Infliximab for Diabetic Macular Edema Refractory to Laser Photocoagulation A randomized, double-blind, placebo-controlled, crossover, 32-week study
Petros P. Sfikakis et al.
DIABETES CARE (2010)
Recombinant Membrane-targeted Form of CD59 Inhibits the Growth of Choroidal Neovascular Complex in Mice
Nalini S. Bora et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Membrane attack complex inhibitor CD59a protects against focal cerebral ischemia in mice
Denise Harhausen et al.
JOURNAL OF NEUROINFLAMMATION (2010)
Complement: a key system for immune surveillance and homeostasis
Daniel Ricklin et al.
NATURE IMMUNOLOGY (2010)
Dendritic cells are early responders to retinal injury
Ute Lehmann et al.
NEUROBIOLOGY OF DISEASE (2010)
Two-Year Outcomes of the Ranibizumab for Edema of the mAcula in Diabetes (READ-2) Study
Quan Dong Nguyen et al.
OPHTHALMOLOGY (2010)
Randomized Trial Evaluating Ranibizumab Plus Prompt or Deferred Laser or Triamcinolone Plus Prompt Laser for Diabetic Macular Edema
Michael J. Elman et al.
OPHTHALMOLOGY (2010)
ProNGF induces TNFα-dependent death of retinal ganglion cells through a p75NTR non-cell-autonomous signaling pathway
Frederic Lebrun-Julien et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
The pivotal role of the complement system in aging and age-related macular degeneration: Hypothesis re-visited
Don H. Anderson et al.
PROGRESS IN RETINAL AND EYE RESEARCH (2010)
ADVERSE EVENTS AFTER INTRAVITREAL INFLIXIMAB (REMICADE)
Monica Giganti et al.
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES (2010)
A Systematic Meta-Analysis of Genetic Association Studies for Diabetic Retinopathy
Sotoodeh Abhary et al.
DIABETES (2009)
Protective role of pigment epithelium-derived factor (PEDF) in early phase of experimental diabetic retinopathy
Yumiko Yoshida et al.
DIABETES-METABOLISM RESEARCH AND REVIEWS (2009)
Resting Microglia Directly Monitor the Functional State of Synapses In Vivo and Determine the Fate of Ischemic Terminals
Hiroaki Wake et al.
JOURNAL OF NEUROSCIENCE (2009)
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
Matthew G. Vander Heiden et al.
SCIENCE (2009)
Differential Regulation of High Glucose-Induced Glyceraldehyde-3-Phosphate Dehydrogenase Nuclear Accumulation in Muller Cells by IL-1 beta and IL-6
E. Chepchumba K. Yego et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2009)
Scavenger Function of Resident Autofluorescent Perivascular Macrophages and Their Contribution to the Maintenance of the Blood-Retinal Barrier
Luisa Mendes-Jorge et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2009)
Complement regulators and inhibitory proteins
Peter F. Zipfel et al.
NATURE REVIEWS IMMUNOLOGY (2009)
Microglial activation in human diabetic retinopathy
Hui-yang Zeng et al.
ARCHIVES OF OPHTHALMOLOGY (2008)
Combined rhegmatogenous and traction retinal detachment in proliferative diabetic retinopathy: clinical manifestations and surgical outcome
Chung-May Yang et al.
CANADIAN JOURNAL OF OPHTHALMOLOGY-JOURNAL CANADIEN D OPHTALMOLOGIE (2008)
Induction of immunological tolerance by apoptotic cells requires caspase-dependent oxidation of high-mobility group box-1 protein
Hirotaka Kazama et al.
IMMUNITY (2008)
Ex vivo dynamic imaging of retinal microglia using time-lapse confocal microscopy
Jung Eun Lee et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2008)
Origin and physiological roles of inflammation
Ruslan Medzhitov
NATURE (2008)
Proinflammatory cytokines and angiogenic and anti-angiogenic factors in vitreous of patients with proliferative diabetic retinopathy and Eales' disease
Ponnalagu Murugeswari et al.
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES (2008)
Local diabetic retinopathy prediction by multifocal ERG delays over 3 years
Jason S. Ng et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2008)
Concentration of haemodynamic and inflammatory related cytokines in diabetic retinopathy
J. I. Patel et al.
EYE (2008)
MCP-1 deficiency delays regression of pathologic retinal neovascularization in a model of ischemic retinopathy
Michael H. Davies et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2008)
The classical complement cascade mediates CNS synapse elimination
Beth Stevens et al.
CELL (2007)
Fractalkine, a CX3C chemokine, as a mediator of ocular angiogenesis
Jian-Jang You et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2007)
Role of the fas-signaling pathway in photoreceptor neuroprotection
David N. Zacks et al.
ARCHIVES OF OPHTHALMOLOGY (2007)
Retinal vessel caliber and microvascular and macrovascular disease in type 2 diabetes - XXI: The Wisconsin Epidemiologic Study of Diabetic Retinopathy
Ronald Klein et al.
OPHTHALMOLOGY (2007)
CX3CR1-dependent subretinal microglia cell accumulation is associated with cardinal features of age-related macular degeneration
Christophe Combadiere et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Signalling within the neurovascular unit in the mammalian retina
Monica R. Metea et al.
EXPERIMENTAL PHYSIOLOGY (2007)
Interleukin-6 receptor-mediated activation of signal transducer and activator of transcription-3 (STAT3) promotes choroidal neovascularization
Kanako Izumi-Nagai et al.
AMERICAN JOURNAL OF PATHOLOGY (2007)
AGEs mediated expression and secretion of TNF alpha in rail retinal microglia
Ai Ling Wang et al.
EXPERIMENTAL EYE RESEARCH (2007)
Identification of novel dendritic cell populations in normal mouse retina
Heping Xu et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2007)
Myeloid progenitors differentiate into microglia and promote vascular repair in a model of ischemic retinopathy
Matthew R. Ritter et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Determination of vitreous interleukin-1 (IL-1) and tumour necrosis factor (TNF) levels in proliferative diabetic retinopathy
N. Demircan et al.
EYE (2006)
Diabetes alters osmotic swelling characteristics and membrane conductance of glial cells in rat retina
T Pannicke et al.
DIABETES (2006)
Pigment epithelium-derived factor (PEDF) is an endogenous antiinflammatory factor
Sarah X. Zhang et al.
FASEB JOURNAL (2006)
The Ins2Akita mouse as a model of early retinal complications in diabetes
AJ Barber et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2005)
Interleukin-8, monocyte chemoattractant protein-1 and IL-10 in the vitreous fluid of patients with proliferative diabetic retinopathy
C Hernández et al.
DIABETIC MEDICINE (2005)
Minocycline reduces proinflammatory cytokine expression, microglial activation, and caspase-3 activation in a rodent model of diabetic retinopathy
JK Krady et al.
DIABETES (2005)
The characterisation of hyalocytes: the origin, phenotype, and turnover
H Qiao et al.
BRITISH JOURNAL OF OPHTHALMOLOGY (2005)
Expression of acute-phase response proteins in retinal Muller cells in diabetes
C Gerhardinger et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2005)
Inhibition of tumor necrosis factor-α improves physiological angiogenesis and reduces pathological neovascularization in ischemic retinopathy
TA Gardiner et al.
AMERICAN JOURNAL OF PATHOLOGY (2005)
Chronically elevated glucose-induced apoptosis by inactivation of Akt in cultured Muller cells
X Xi et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Microglia promote the death of developing Purkinje cells
JL Marín-Teva et al.
NEURON (2004)
Death of retinal neurons in streptozotocin-induced diabetic mice
PM Martin et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2004)
Neuroprotective and antiangiogenic actions of PEDF in the eye: molecular targets and therapeutic potential
CJ Barnstable et al.
PROGRESS IN RETINAL AND EYE RESEARCH (2004)
Differential expression of connective tissue growth factor in microglia and pericytes in the human diabetic retina
EJ Kuiper et al.
BRITISH JOURNAL OF OPHTHALMOLOGY (2004)
Impaired synaptic function in the microglial KARAP/DAP12-deficient mouse
A Roumier et al.
JOURNAL OF NEUROSCIENCE (2004)
Expression of apoptosis markers in the retinas of human subjects with diabetes
AM Abu El-Asrar et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2004)
A central role for inflammation in the pathogenesis of diabetic retinopathy
AM Joussen et al.
FASEB JOURNAL (2004)
Reduced response of retinal vessel diameters to flicker stimulation in patients with diabetes
G Garhöfer et al.
BRITISH JOURNAL OF OPHTHALMOLOGY (2004)
Neuropeptide Y-evoked proliferation of retinal glial (Muller) cells
I Milenkovic et al.
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY (2004)
Blocking CD200-CD200 receptor axis augments NOS-2 expression and aggravates experimental autoimmune uveoretinitis in Lewis rats
D Banerjee et al.
OCULAR IMMUNOLOGY AND INFLAMMATION (2004)
Glycation inactivation of the complement regulatory protein CD59 - A possible role in the pathogenesis of the vascular complications of human diabetes
XB Qin et al.
DIABETES (2004)
Induction of IL-8, MCP-1, and bFGF by TNF-α in retinal glial cells:: implications for retinal neovascularization during post-ischemic inflammation
S Yoshida et al.
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY (2004)
Proposed international clinical diabetic retinopathy and diabetic macular edema disease severity scales
CP Wilkinson et al.
OPHTHALMOLOGY (2003)
The role of advanced glycation in the pathogenesis of diabetic retinopathy
AW Stitt
EXPERIMENTAL AND MOLECULAR PATHOLOGY (2003)
CD45-positive cells of the retina and their responsiveness to in vivo and in vitro treatment with IFN-γ or anti-CD40
DS Gregerson et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2003)
Low content of the natural ocular anti-angiogenic agent pigment epithelium-derived factor (PEDF) in aqueous humor predicts progression of diabetic retinopathy
BO Boehm et al.
DIABETOLOGIA (2003)
Tractional force generation by human Muller cells: Growth factor responsiveness and integrin receptor involvement
C Guidry et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2003)
TGF beta directs gene expression of activated microglia to an anti-inflammatory phenotype strongly focusing on chemokine genes and cell migratory genes
R Paglinawan et al.
GLIA (2003)
Constitutive retinal CD200 expression regulates resident microglia and activation state of inflammatory cells during experimental autoimmune uveoretinitis
C Broderick et al.
AMERICAN JOURNAL OF PATHOLOGY (2002)
Suppression of Fas-FasL-induced endothelial cell apoptosis prevents diabetic blood-retinal barrier breakdown in a model of streptozotocin-induced diabetes
AM Joussen et al.
FASEB JOURNAL (2002)
Retinal arteriolar narrowing and risk of diabetes mellitus in middle-aged persons
TY Wong et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2002)
Immunobiology and privilege of neuronal retina and pigment epithelium transplants
JW Streilein et al.
VISION RESEARCH (2002)
Increased levels of vascular endothelial growth factor and interleukin-6 in the aqueous humor of diabetics with macular edema
H Funatsu et al.
AMERICAN JOURNAL OF OPHTHALMOLOGY (2002)
Anti-inflammatory antioxidants attenuate the expression of inducible nitric oxide synthase mediated by advanced glycation endproducts in murine microglia
A Wong et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2001)
Zebrafish early macrophages colonize cephalic mesenchyme and developing brain, retina, and epidermis through, a M-CSF receptor-dependent invasive process
P Herbomel et al.
DEVELOPMENTAL BIOLOGY (2001)
Advances in immunology: Complement (First of two parts).
MJ Walport
NEW ENGLAND JOURNAL OF MEDICINE (2001)
Stereo nonmydriatic digital-video color retinal imaging compared with early treatment diabetic retinopathy study seven standard field 35-mm stereo color photos for determining level of diabetic retinopathy
SE Bursell et al.
OPHTHALMOLOGY (2001)
Leukocyte-mediated endothelial cell injury and death in the diabetic retina
AM Joussen et al.
AMERICAN JOURNAL OF PATHOLOGY (2001)
Down-regulation of the macrophage lineage through interaction with OX2 (CD200)
RM Hoek et al.
SCIENCE (2000)
Vascular endothelial growth factor (VEGF)-induced retinal vascular permeability is mediated by intercellular adhesion molecule-1 (ICAM-1)
K Miyamoto et al.
AMERICAN JOURNAL OF PATHOLOGY (2000)